237 research outputs found
Estradiol, Progesterone, and Transforming Growth Factor α Regulate Insulin-Like Growth Factor Binding Protein-3 (IGFBP3) Expression in Mouse Endometrial Cells
Insulin-like growth factor 1 (IGF1) Is Involved in the proliferation of mouse and rat endometrial cells in a paracrine or autocrine manner. Insulin-like growth factor binding protein-3 (IGFBP3) modulates actions of IGFs directly or indirectly. The present study aimed to determine whether IGFBP3 is Involved In the regulation of proliferation of mouse endometrial cells. Mouse endometrial epithelial cells and stromal cells were isolated, and cultured In a serum free medium. IGF1 stimulated DNA synthesis by endometrial epithelial and stromal cells, and IGFBP3 Inhibited IGF1-induced DNA synthesis. Estradiol-17 beta (E2) decreased the Igfbp3 mRNA level in endometrial stromal cells, whereas It Increased the Igf1 mRNA level. Transforming growth factor alpha (TGF alpha) significantly decreased IGFBP3 expression at both the mRNA and secreted protein levels in endometrial stromal cells. Progesterone (134) did not affect the E2-induced down-regulation of Igfbp3 mRNA expression in endometrial stromal cells, although P4 alone increased Igfbp3 mRNA levels. The present findings suggest that in mouse endometrial stromal cells E2 enhances IGF1 action through enhancement of IGF1 synthesis and reduction of IGFBP3 synthesis, and that TGF alpha affects IGF1 actions through modulation of IGFBP3 levels
Orbital-selective confinement effect of Ru orbitals in SrRuO ultrathin film
The electronic structure of SrRuO thin film with thickness from 50 to 1
unit cell (u.c.) is investigated via the resonant inelastic x-ray scattering
(RIXS) technique at the O K-edge to unravel the intriguing interplay of orbital
and charge degrees of freedom. We found that orbital-selective quantum
confinement effect (QCE) induces the splitting of Ru orbitals. At the same
time, we observed a clear suppression of the electron-hole continuum across the
metal-to-insulator transition (MIT) occurring at the 4 u.c. sample. From these
two clear observations we conclude that QCE gives rise to a Mott insulating
phase in ultrathin SrRuO films. Our interpretation of the RIXS spectra is
supported by the configuration interaction calculations of RuO clusters.Comment: 7 pages, 7 figure
Orbital Wave and its Observation in Orbital Ordered Titanates and Vanadates
We present a theory of the collective orbital excitation termed orbital wave
in perovskite titanates and vanadates with the triply degenerate
orbitals. The dispersion relations of the orbital waves for the orbital ordered
LaVO, YVO and YTiO are examined in the effective spin-orbital
coupled Hamiltonians associated with the Jahn-Teller type couplings. We propose
possible scattering processes for the Raman and inelastic neutron scatterings
from the orbital wave and calculate the scattering spectra for titanates and
vanadates. It is found that both the excitation spectra and the observation
methods of the orbital wave are distinct qualitatively from those for the
orbital ordered systems.Comment: 9 pages, 7 figure
Polarization Dependence of Anomalous X-ray Scattering in Orbital Ordered Manganites
In order to determine types of the orbital ordering in manganites, we study
theoretically the polarization dependence of the anomalous X-ray scattering
which is caused by the anisotropy of the scattering factor. The general
formulae of the scattering intensity in the experimental optical system is
derived and the atomic scattering factor is calculated in the microscopic
electronic model. By using the results, the X-ray scattering intensity in
several types of the orbital ordering is numerically calculated as a function
of azimuthal and analyzer angles.Comment: 9 pages, 7 figure
Temperature dependence of the resistivity in the double-exchange model
The resistivity around the ferromagnetic transition temperature in the double
exchange model is studied by the Schwinger boson approach. The spatial spin
correlation responsible for scattering of conduction electrons are taken into
account by adopting the memory function formalism. Although the correlation
shows a peak lower than the transition temperature, the resistivity in the
ferromagnetic state monotonically increases with increasing temperature due to
a variation of the electronic state of the conduction electron. In the
paramagnetic state, the resistivity is dominated by the short range correlation
of scattering and is almost independent of the temperature. It is attributed to
a cancellation between the nearest-neighbor spin correlation, the fermion
bandwidth, and the fermion kinetic energy. This result implies the importance
of the temperature dependence of the electronic states of the conduction
electron as well as the localized spin states in both ferromagnetic and
paramagnetic phases.Comment: RevTex, 4 pages, 4 PostScript figures, To appear in Phys. Rev.
Theory of Orbital Ordering, Fluctuation and Resonant X-ray Scattering in Manganites
A theory of resonant x-ray scattering in perovskite manganites is developed
by applying the group theory to the correlation functions of the pseudospin
operators for the orbital degree of freedom. It is shown that static and
dynamical informations of the orbital state are directly obtained from the
elastic, diffuse and inelastic scatterings due to the tensor character of the
scattering factor. We propose that the interaction and its anisotropy between
orbitals are directly identified by the intensity contour of the diffuse
scattering in the momentum space.Comment: 4 pages, 1 figur
30 inch Roll-Based Production of High-Quality Graphene Films for Flexible Transparent Electrodes
We report that 30-inch scale multiple roll-to-roll transfer and wet chemical
doping considerably enhance the electrical properties of the graphene films
grown on roll-type Cu substrates by chemical vapor deposition. The resulting
graphene films shows a sheet resistance as low as ~30 Ohm/sq at ~90 %
transparency which is superior to commercial transparent electrodes such as
indium tin oxides (ITO). The monolayer of graphene shows sheet resistances as
low as ~125 Ohm/sq with 97.4% optical transmittance and half-integer quantum
Hall effect, indicating the high-quality of these graphene films. As a
practical application, we also fabricated a touch screen panel device based on
the graphene transparent electrodes, showing extraordinary mechanical and
electrical performances
Resonant X-ray Scattering in Manganites - Study of Orbital Degree of Freedom -
Orbital degree of freedom of electrons and its interplay with spin, charge
and lattice degrees of freedom are one of the central issues in colossal
magnetoresistive manganites. The orbital degree of freedom has until recently
remained hidden, since it does not couple directly to most of experimental
probes. Development of synchrotron light sources has changed the situation; by
the resonant x-ray scattering (RXS) technique the orbital ordering has
successfully been observed . In this article, we review progress in the recent
studies of RXS in manganites. We start with a detailed review of the RXS
experiments applied to the orbital ordered manganites and other correlated
electron systems. We derive the scattering cross section of RXS where the
tensor character of the atomic scattering factor (ASF) with respect to the
x-ray polarization is stressed. Microscopic mechanisms of the anisotropic
tensor character of ASF is introduced and numerical results of ASF and the
scattering intensity are presented. The azimuthal angle scan is a unique
experimental method to identify RXS from the orbital degree of freedom. A
theory of the azimuthal angle and polarization dependence of the RXS intensity
is presented. The theoretical results show good agreement with the experiments
in manganites. Apart from the microscopic description of ASF, a theoretical
framework of RXS to relate directly to the 3d orbital is presented. The
scattering cross section is represented by the correlation function of the
pseudo-spin operator for the orbital degree of freedom. A theory is extended to
the resonant inelastic x-ray scattering and methods to observe excitations of
the orbital degree of freedom are proposed.Comment: 47 pages, 24 figures, submitted to Rep. Prog. Phy
Interplay of Electron-Phonon Interaction and Electron Correlation in High Temperature Superconductivity
We study the electron-phonon interaction in the strongly correlated
superconducting cuprates. Two types of the electron-phonon interactions are
introduced in the model; the diagonal and off-diagonal interactions which
modify the formation energy of the Zhang-Rice singlet and its transfer
integral, respectively. The characteristic phonon-momentum and
electron-momentum dependence resulted from the off-diagonal coupling
can explain a variety of experiments. The vertex correction for the
electron-phonon interaction is formulated in the SU(2) slave-boson theory by
taking into account the collective modes in the superconducting ground states.
It is shown that the vertex correction enhances the attractive potential for
the d-wave paring mediated by phonon with around
which corresponds to the half-breathing mode of the oxygen
motion.Comment: 14 pages, 13 figure
Genome sequence of an Australian kangaroo, Macropus eugenii, provides insight into the evolution of mammalian reproduction and development.
BACKGROUND: We present the genome sequence of the tammar wallaby, Macropus eugenii, which is a member of the kangaroo family and the first representative of the iconic hopping mammals that symbolize Australia to be sequenced. The tammar has many unusual biological characteristics, including the longest period of embryonic diapause of any mammal, extremely synchronized seasonal breeding and prolonged and sophisticated lactation within a well-defined pouch. Like other marsupials, it gives birth to highly altricial young, and has a small number of very large chromosomes, making it a valuable model for genomics, reproduction and development. RESULTS: The genome has been sequenced to 2 × coverage using Sanger sequencing, enhanced with additional next generation sequencing and the integration of extensive physical and linkage maps to build the genome assembly. We also sequenced the tammar transcriptome across many tissues and developmental time points. Our analyses of these data shed light on mammalian reproduction, development and genome evolution: there is innovation in reproductive and lactational genes, rapid evolution of germ cell genes, and incomplete, locus-specific X inactivation. We also observe novel retrotransposons and a highly rearranged major histocompatibility complex, with many class I genes located outside the complex. Novel microRNAs in the tammar HOX clusters uncover new potential mammalian HOX regulatory elements. CONCLUSIONS: Analyses of these resources enhance our understanding of marsupial gene evolution, identify marsupial-specific conserved non-coding elements and critical genes across a range of biological systems, including reproduction, development and immunity, and provide new insight into marsupial and mammalian biology and genome evolution
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