1,401 research outputs found

    E-Government implementation Challenges: A Case study

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    The purpose of this paper is to explore empirically the implementation of e-government in a developing country in the Gulf Cooperation Countries (GCC) and the key challenges that influence implementation. A case study (using interview-based research) was undertaken within the State of Qatar. After reviewing the available literature, the paper first proposes a conceptual model, which was then used to explore e-government related change by considering the key forces influencing implementation from an organisational, technological, social and political context. The empirical results confirmed previously findings in literature and identified a number of new issues that were influencing e-government implementation in Qatar which were not explicitly discussed in prior e-government research

    Pursuing Parameters for Critical Density Dark Matter Models

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    We present an extensive comparison of models of structure formation with observations, based on linear and quasi-linear theory. We assume a critical matter density, and study both cold dark matter models and cold plus hot dark matter models. We explore a wide range of parameters, by varying the fraction of hot dark matter Ων\Omega_{\nu}, the Hubble parameter hh and the spectral index of density perturbations nn, and allowing for the possibility of gravitational waves from inflation influencing large-angle microwave background anisotropies. New calculations are made of the transfer functions describing the linear power spectrum, with special emphasis on improving the accuracy on short scales where there are strong constraints. For assessing early object formation, the transfer functions are explicitly evaluated at the appropriate redshift. The observations considered are the four-year {\it COBE} observations of microwave background anisotropies, peculiar velocity flows, the galaxy correlation function, and the abundances of galaxy clusters, quasars and damped Lyman alpha systems. Each observation is interpreted in terms of the power spectrum filtered by a top-hat window function. We find that there remains a viable region of parameter space for critical-density models when all the dark matter is cold, though hh must be less than 0.5 before any fit is found and nn significantly below unity is preferred. Once a hot dark matter component is invoked, a wide parameter space is acceptable, including n1n\simeq 1. The allowed region is characterized by \Omega_\nu \la 0.35 and 0.60 \la n \la 1.25, at 95 per cent confidence on at least one piece of data. There is no useful lower bound on hh, and for curious combinations of the other parameters it is possible to fit the data with hh as high as 0.65.Comment: 19 pages LaTeX file (uses mn.sty). Figures *not* included due to length. We strongly recommend obtaining the full paper, either by WWW at http://star-www.maps.susx.ac.uk/papers/lsstru_papers.html (UK) or http://www.bartol.udel.edu/~bob/papers (US), or by e-mailing ARL. Final version, to appear MNRAS. Main revision is update to four-year COBE data. Miscellaneous other changes and reference updates. No significant changes to principal conclusion

    Saprophytic colonization of the bark by Neofusicoccum species mediates subsequent infection of grapevines through wounds

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    Botryosphaeriaceae species infect grapevines via wounds. A previous study isolated Botryosphaeriaceae at higher frequencies from the bark than the underlying wood of asymptomatic grapevines canes from vineyards,suggesting they were latent on surface tissues. This study investigated the colonization of the bark as a saprophytic link to infection of the underlying wood. The bark of trunks of Sauvignon blanc and Pinot noir potted vines were inoculated by spraying an area of 3 cm length with ~1 mL of a Neofusicoccum luteum or N. parvum conidial suspensions (10⁴/mL). Control vines were inoculated with sterile water. After 1 hour (T1), 2 days (T2) or 7 days (T3) a cut was made in the bark and through to the wood 1 cm above the inoculation area using a sterile scalpel. After 24 h, isolations were carried out from surface sterilized bark and wood. Infection incidence did not differ significantly between species or grapevine cultivar. Infection incidence of the bark was 100% and associated wood of the central inoculated section was 76.3%, 83.3% and 90.2% for T1, T2 and T3, respectively indicating bark infection progressed rapidly into the adjacent wood. Infection of bark and wood 1 cm above the inoculation point increased with incubation time, being 25% for bark and wood at T1 and 71% and 67% for bark and wood, respectively at T3. Infection of the bark and wood 1 cm below the inoculated area was 0%. This study showed that the pathogens remained latent in the bark and, when the cane was wounded, that the pathogen progressed towards the wound. Fluorescent microscopic observations of bark and underlying wood sections of shoots inoculated onto the bark, but without wounding, showed germinating conidia and mycelium in the bark near lenticels, and mycelia in the underlying wood, indicating that the pathogens had entered through lenticels

    Fine needle aspiration cytology in parotid lumps

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    Over a period of two years, Fine Needle Aspiration Cytology (FNAC) was performed on 33 patients presenting with a parotid lump. Five patients were excluded as they were treated medically after FNAC report. The FNAC results of 28 cases were compared with histopathological diagnoses of surgically resected specimens. There were 8 true positive, 17 true negative, 1 false positive and 2 false negative cases. Sensitivity was 80%, specificity 94.4% and diagnostic accuracy 89.3%. FNAC is a simple quick, accurate and virtually complications free investigative modality. It is also helpful adjunct to assess preoperatively the suitability and extent of the surgical treatment

    Inferior paralabral ganglion cyst of the shoulder with labral tear - A rare cause of shoulder pain

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    SummaryIntroductionParalabral ganglion cysts of the shoulder are rare, and their pathogenesis is similar to that of meniscal cysts. The paralabral cysts are most frequently reported along the posterior, superior, and anterior aspects of the glenohumeral joint and are uncommon inferiorly to the joint. These cysts rarely become evident clinically, unless they cause compression of surrounding structures, i.e. nerve.Patients and methodsWe report a retrospective series of five patients with inferior paralabral ganglion cysts of the shoulder without compression of the surrounding nerve which were treated during the period from March 2007 to December 2009. All these patients presented with only chronic shoulder pain as their chief complaint, and preoperative MRI showed the cyst over the inferior aspect of a torn glenoid labrum. All patients were treated by arthroscopic cystic decompression with labrum repair. All patients were re-evaluated with MRI performed at an average of 15 months postoperatively. The clinical outcome, including the Constant score, was assessed for all patients at a median of 16 months postoperatively.ResultsAll the five patients had remission of pain and were satisfied with the shoulder function. The postoperative MRI in all patients showed no labral cyst recurrence. The median Constant score improved from a preoperative level of 81.5 points to 98.0 points at last follow-up.ConclusionThis study demonstrates that, in the absence of any nerve compression symptoms around the shoulder joint, inferior paralabral cysts with labral tear also be considered in the differential diagnosis of chronic shoulder pain. Arthroscopic repair of the cyst with repair of the labrum can lead to the disappearance of symptoms. Knowledge of this clinical condition and its imaging features is critical for a correct diagnosis of this uncommon cause of chronic shoulder pain.Level of evidenceLevel IV. Retrospective therapeutic study

    Effect of different solvent extracted sample of Allium sativum (Linn) on bacteria and fungi

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    This study was aimed to evaluate the antimicrobial activity of garlic-extracted samples against bacteria and fungi at different concentration, in various polar solvents. For this purpose, six different extracts were prepared, using five different polar solvents (methanol, ethyl acetate, petroleum ether, chloroforms and butanol) and water. Two different concentrations (1 and 2 mg disc-1) of each extract were subjected for preliminary antibacterial screening against seven pathogenic bacteria by Kirby- Bauer disk diffusion method. The result of in vitro antibacterial screening showed that 6 extracts from garlic had different ranges of antibacterial activities. When garlic extracts were studied for their antibacterial potential against Gram-positive bacteria and Gram-negative bacteria, the butanol extracted samples showed the highest inhibitory effect against B. cereus (76% ZI at 2 mg disc-1 concentration). Water extracted samples indicated a good range of inhibitory effect against Salmonella typhi (73% ZI at 2 mg disc-1) and butanol extracted sample showed highest activity against Erwinia carotovora (75% ZI). The data also showed that of petroleum ether, methanol and water did not show any  inhibitory effect against the tested microbes.Key words: Solvent, bacteria, fungi, Allium sativum

    Antimicrobial potentials of Eclipta alba by disc diffusion method

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    This study was conducted to evaluate the antimicrobial potentials of methanol, petroleum ether, dichloromethane, ethyl acetate, butanol and water extracted samples from the aerial parts of Eclipta alba against nine microbial species. The antimicrobial (antibacterial and antifungal) susceptibility was screened by disc diffusion assay. The tested microbial species were Bacillus cereus, Bacillus subtilis, Candida albicans, Erwinia carotovora, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Salmonella typhi and Staphylococcus aureus. The extracts were applied in different concentrations of 1, 2 and 3 mg disc-1. Analysis of the data revealed that all the six extracts from E. alba showed different ranges of antimicrobial activities. Butanol fraction showed inhibitory activities against all the nine microbial species. Ethyl acetate fraction showed inhibitory effects against all the tested microbial species except B. cereus and S. typhi. Petroleum ether, dichloromethane, methanol and water extracted samples had varying levels of inhibitions against some of these microorganisms. The most resistant microbial strain was S. typhi and was not controlled by petroleum ether, dichloromethane, methanol and water extracted samples. The most susceptible Gram positive bacterium was B. subtilis and was inhibited by all the six extracts from E. alba while the most resistant Gram positive bacterium was B. cereus. E. carotovora was the most susceptible Gram negative bacterium while S. typhi and E. coli were highly resistant among the Gram negative bacteria.Key words: Antimicrobial, potential, Eclipta alba, disc diffusion

    Carriage of Staphylococcus aureus in the elderly

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    The point prevalence and incidence of Staphylococcus aureus (methicillin-sensitive and -resistant) carriage by inpatients on acute elderly care wards was estimated. The relationship to body site and to previous admissions to hospital or other institutions was determined. Fifty-five patients were included in the point prevalence study and 136 in the incidence study, which was performed over a two-month period. One in three patients carried S. aureus and 1 in 20 was infected. The incidence rate for MRSA was 2.9%. No endemic strain was found. Nostrils were significantly associated with carriage, and skin break isolates were significant in the point prevalence survey. Screening these sites alone would be most cost effective
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