Solid propellant motor

A case bonded end burning solid propellant rocket motor is described. A propellant with sufficiently low modulus to avoid chamber buckling on cooling from cure and sufficiently high elongation to sustain the stresses induced without cracking is used. The propellant is zone cured within the motor case at high pressures equal to or approaching the pressure at which the motor will operate during combustion. A solid propellant motor with a burning time long enough that its spacecraft would be limited to a maximum acceleration of less than 1 g is provided by one version of the case bonded end burning solid propellant motor of the invention

Applicability of the control configured design approach to advanced earth orbital transportation systems

The applicability of the control configured design approach (CCV) to advanced earth orbital transportation systems was studied. The baseline system investigated was fully reusable vertical take-off/horizontal landing single-stage-to-orbit vehicle and had mission requirements similar to the space shuttle orbiter. Technical analyses were made to determine aerodynamic, flight control and subsystem design characteristics. Figures of merit were assessed on vehicle dry weight and orbital payload. The results indicated that the major parameters for CCV designs are hypersonic trim, aft center of gravity, and control surface heating. Optimized CCV designs can be controllable and provide substantial payload gains over conventional non-CCV design vertical take-off vehicles

Covalent ligation studies on the human telomere quadruplex

Recent X-ray crystallographic studies on the human telomere sequence d[AGGG(TTAGGG)(3)] revealed a unimolecular, parallel quadruplex structure in the presence of potassium ions, while earlier NMR results in the presence of sodium ions indicated a unimolecular, antiparallel quadruplex. In an effort to identify and isolate the parallel form in solution, we have successfully ligated into circular products the single-stranded human telomere and several modified human telomere sequences in potassium-containing solutions. Using these sequences with one or two terminal phosphates, we have made chemically ligated products via creation of an additional loop. Circular products have been identified by polyacrylamide gel electrophoresis, enzymatic digestion with exonuclease VII and electrospray mass spectrometry in negative ion mode. Optimum pH for the ligation reaction of the human telomere sequence ranges from 4.5 to 6.0. Several buffers were also examined, with MES yielding the greatest ligation efficiency. Human telomere sequences with two phosphate groups, one each at the 3′ and 5′ ends, were more efficient at ligation, via pyrophosphate bond formation, than the corresponding sequences with only one phosphate group, at the 5′ end. Circular dichroism spectra showed that the ligation product was derived from an antiparallel, single-stranded guanine quadruplex rather than a parallel single-stranded guanine quadruplex structure

Delta Upsilon : March

https://digitalcommons.library.umaine.edu/mmb-ps/2613/thumbnail.jp

Nonlinearities and Effects of Transverse Beam Size in Beam Position Monitors (revised)

The fields produced by a long beam with a given transverse charge distribution in a homogeneous vacuum chamber are studied. Signals induced by a displaced finite-size beam on electrodes of a beam position monitor (BPM) are calculated and compared to those produced by a pencil beam. The non-linearities and corrections to BPM signals due to a finite transverse beam size are calculated for an arbitrary chamber cross section. Simple analytical expressions are given for a few particular transverse distributions of the beam current in a circular or rectangular chamber. Of particular interest is a general proof that in an arbitrary homogeneous chamber the beam-size corrections vanish for any axisymmetric beam current distribution.Comment: REVTeX, 8 pages, 9 figures. Corrected Eqs. (7),(22),(25) and Figs. 2-9. Expande

Array processor architecture connection network

A connection network is disclosed for use between a parallel array of processors and a parallel array of memory modules for establishing non-conflicting data communications paths between requested memory modules and requesting processors. The connection network includes a plurality of switching elements interposed between the processor array and the memory modules array in an Omega networking architecture. Each switching element includes a first and a second processor side port, a first and a second memory module side port, and control logic circuitry for providing data connections between the first and second processor ports and the first and second memory module ports. The control logic circuitry includes strobe logic for examining data arriving at the first and the second processor ports to indicate when the data arriving is requesting data from a requesting processor to a requested memory module. Further, connection circuitry is associated with the strobe logic for examining requesting data arriving at the first and the second processor ports for providing a data connection therefrom to the first and the second memory module ports in response thereto when the data connection so provided does not conflict with a pre-established data connection currently in use

RNA-Interference Knockdown of Drosophila Pigment Dispersing Factor in Neuronal Subsets: The Anatomical Basis of a Neuropeptide's Circadian Functions

Background: In animals, neuropeptide signaling is an important component of circadian timekeeping. The neuropeptide pigment dispersing factor (PDF) is required for several aspects of circadian activity rhythms in Drosophila. Methodology/Principal Findings: Here we investigate the anatomical basis for PDF’s various circadian functions by targeted PDF RNA-interference in specific classes of Drosophila neuron. We demonstrate that PDF is required in the ventrolateral neurons (vLNs) of the central brain and not in the abdominal ganglion for normal activity rhythms. Differential knockdown of PDF in the large or small vLNs indicates that PDF from the small vLNs is likely responsible for the maintenance of free-running activity rhythms and that PDF is not required in the large vLNs for normal behavior. PDF’s role in setting the period of free-running activity rhythms and the proper timing of evening activity under light:dark cycles emanates from both subtypes of vLN, since PDF in either class of vLN was sufficient for these aspects of behavior. Conclusions/Significance: These results reveal the neuroanatomical basis PDF’s various circadian functions and refine ou

Array processor architecture

A high speed parallel array data processing architecture fashioned under a computational envelope approach includes a data base memory for secondary storage of programs and data, and a plurality of memory modules interconnected to a plurality of processing modules by a connection network of the Omega gender. Programs and data are fed from the data base memory to the plurality of memory modules and from hence the programs are fed through the connection network to the array of processors (one copy of each program for each processor). Execution of the programs occur with the processors operating normally quite independently of each other in a multiprocessing fashion. For data dependent operations and other suitable operations, all processors are instructed to finish one given task or program branch before all are instructed to proceed in parallel processing fashion on the next instruction. Even when functioning in the parallel processing mode however, the processors are not locked-step but execute their own copy of the program individually unless or until another overall processor array synchronization instruction is issued

Asymptotic equivalence of homogenisation procedures and fine-tuning of continuum theories

Long-wave models obtained in the process of asymptotic homogenisation of structures with a characteristic length scale are known to be non-unique. The term non-uniqueness is used here in the sense that various homogenisation strategies may lead to distinct governing equations that usually, for a given order of the governing equation, approximate the original problem with the same asymptotic accuracy. A constructive procedure presented in this paper generates a class of asymptotically equivalent long-wave models from an original homogenised theory. The described non-uniqueness manifests itself in the occurrence of additional parameters characterising the model. A simple problem of long-wave propagation in a regular one-dimensional lattice structure is used to illustrate important criteria for selecting these parameters. The procedure is then applied to derive a class of continuum theories for a two-dimensional square array of particles. Applications to asymptotic structural theories are also discussed. In particular, we demonstrate how to improve the governing equation for the Rayleigh-Love rod and explain the reasons for the well-known numerical accuracy of the Mindlin plate theory