4,336 research outputs found

    Lithics in the West: Using Lithic Analysis to Solve Archeological Problems in Western North America

    Get PDF
    Lithics in the West seeks to link the rich archaeological lithic data base from the western United States with some of the contemporary theoretical and analytical approaches used in global settings in stone tool and debitage analysis today. The book highlights the role that lithic analysis (in all its forms) plays in solving research problems in the prehistory of western North America. The book covers important archaeological sites and projects in Montana, Wyoming, Idaho, Colorado, and Washington. Contributors include William Andrefsky, Jr., Robert Kelly, Nicole Waguespack, Pei-Lin Yu, Doug MacDonald, Robert Brunswig, Scott Carpenter, Jackie Cook, David Diggs, Philip Fisher, Katie Harris, Brian Ostahowski, Mary Prasciunas, Ken Reid, and Todd Surovell.https://scholarworks.umt.edu/umpress-oabooks/1000/thumbnail.jp

    DeepTrace: Learning to Optimize Contact Tracing in Epidemic Networks with Graph Neural Networks

    Full text link
    The goal of digital contact tracing is to diminish the spread of an epidemic or pandemic by detecting and mitigating public health emergencies using digital technologies. Since the start of the COVID-1919 pandemic, a wide variety of mobile digital apps have been deployed to identify people exposed to the SARS-CoV-2 coronavirus and to stop onward transmission. Tracing sources of spreading (i.e., backward contact tracing), as has been used in Japan and Australia, has proven crucial as going backwards can pick up infections that might otherwise be missed at superspreading events. How should robust backward contact tracing automated by mobile computing and network analytics be designed? In this paper, we formulate the forward and backward contact tracing problem for epidemic source inference as maximum-likelihood (ML) estimation subject to subgraph sampling. Besides its restricted case (inspired by the seminal work of Zaman and Shah in 2011) when the full infection topology is known, the general problem is more challenging due to its sheer combinatorial complexity, problem scale and the fact that the full infection topology is rarely accurately known. We propose a Graph Neural Network (GNN) framework, named DeepTrace, to compute the ML estimator by leveraging the likelihood structure to configure the training set with topological features of smaller epidemic networks as training sets. We demonstrate that the performance of our GNN approach improves over prior heuristics in the literature and serves as a basis to design robust contact tracing analytics to combat pandemics

    Green tea inhibited the elimination of nephro-cardiovascular toxins and deteriorated the renal function in rats with renal failure

    Get PDF
    Chronic kidney disease (CKD) is a major health problem worldwide. Indoxyl sulfate (IS) and p-cresyl sulfate (PCS) are highly protein-bound nephro-cardiovascular toxins, which are not efficiently removed through hemodialysis. The renal excretions of IS and PCS were mediated by organic anion transporters (OATs) such as OAT1 and OAT3. Green tea (GT) is a popular beverage containing plenty of catechins. Previous pharmacokinetic studies of teas have shown that the major molecules present in the bloodstream are the glucuronides/sulfates of tea catechins, which are putative substrates of OATs. Here we demonstrated that GT ingestion significantly elevated the systemic exposures of endogenous IS and PCS in rats with chronic renal failure (CRF). More importantly, GT also significantly increased the levels of serum creatinine (Cr) and blood urea nitrogen (BUN) in CRF rats. Mechanism studies indicated that the serum metabolites of GT (GTM) inhibited the uptake transporting functions of OAT1 and OAT3. In conclusion, GT inhibited the elimination of nephro-cardiovascular toxins such as IS and PCS, and deteriorated the renal function in CRF rats

    Heat statistics in the relaxation process of the Edwards-Wilkinson elastic manifold

    Full text link
    The stochastic thermodynamics of systems with a few degrees of freedom has been studied extensively so far. We would like to extend the study to systems with more degrees of freedom and even further-continuous fields with infinite degrees of freedom. The simplest case for a continuous stochastic field is the Edwards-Wilkinson elastic manifold. It is an exactly solvable model of which the heat statistics in the relaxation process can be calculated analytically. The cumulants require a cutoff spacing to avoid ultra-violet divergence. The scaling behavior of the heat cumulants with time and the system size as well as the large deviation rate function of the heat statistics in the large size limit is obtained

    Fatigue Properties and Damage Mechanism of a Cr-Mn Austenite Steel

    Get PDF
    The fatigue properties and the damage mechanism of a Cr-Mn austenite steel were investigated using four-point bend fatigue testing. The stress-number of cycles to failure (S-N) curve of the Cr-Mn austenite steel was measured at room temperature, at the frequency of f=20 Hz and the stress ratio of R=0.1. The fatigue strength of this Cr-Mn austenite steel was measured to be 503 MPa in the maximum stress. Multiple cracks are initiated on the sample surface after fatigue failure tests, and usually only one or two of them can lead to the final failure of the samples. Most of the cracks are initiated at the {111 }primary slip bands, especially within coarse grains. When a fatigue crack meets a new grain, it adapts to slip bands in this grain and hardly extends along the foregoing route in the previous grain. A crack is deflected at a grain boundary by crack plane twisting and tiling on the grain boundary plane, causing fracture steps on the fracture surface

    Large-scale Graphitic Thin Films Synthesized on Ni and Transferred to Insulators: Structural and Electronic Properties

    Get PDF
    We present a comprehensive study of the structural and electronic properties of ultrathin films containing graphene layers synthesized by chemical vapor deposition (CVD) based surface segregation on polycrystalline Ni foils then transferred onto insulating SiO2/Si substrates. Films of size up to several mm's have been synthesized. Structural characterizations by atomic force microscopy (AFM), scanning tunneling microscopy (STM), cross-sectional transmission electron microscopy (XTEM) and Raman spectroscopy confirm that such large scale graphitic thin films (GTF) contain both thick graphite regions and thin regions of few layer graphene. The films also contain many wrinkles, with sharply-bent tips and dislocations revealed by XTEM, yielding insights on the growth and buckling processes of the GTF. Measurements on mm-scale back-gated transistor devices fabricated from the transferred GTF show ambipolar field effect with resistance modulation ~50% and carrier mobilities reaching ~2000 cm^2/Vs. We also demonstrate quantum transport of carriers with phase coherence length over 0.2 ÎĽ\mum from the observation of 2D weak localization in low temperature magneto-transport measurements. Our results show that despite the non-uniformity and surface roughness, such large-scale, flexible thin films can have electronic properties promising for device applications.Comment: This version (as published) contains additional data, such as cross sectional TEM image

    Noncommutative D-Brane in Non-Constant NS-NS B Field Background

    Get PDF
    We show that when the field strength H of the NS-NS B field does not vanish, the coordinates X and momenta P of an open string endpoints satisfy a set of mixed commutation relations among themselves. Identifying X and P with the coordinates and derivatives of the D-brane world volume, we find a new type of noncommutative spaces which is very different from those associated with a constant B field background.Comment: 11 pages, Latex, minor modification

    Cryptic diversity found in Didymellaceae from Australian native legumes

    Get PDF
    Ascochyta koolunga (Didymellaceae, Pleosporales) was first described in 2009 (as Phoma koolunga) and identified as the causal agent of Ascochyta blight of Pisum sativum (field pea) in South Australia. Since then A. koolunga has not been reported anywhere else in the world, and its origins and occurrence on other legume (Fabaceae) species remains unknown. Blight and leaf spot diseases of Australian native, pasture and naturalised legumes were studied to investigate a possible native origin of A. koolunga. Ascochyta koolunga was not detected on native, naturalised or pasture legumes that had leaf spot symptoms, in any of the studied regions in southern Australia, and only one isolate was recovered from P. sativum. However, we isolated five novel species in the Didymellaceae from leaf spots of Australian native legumes from commercial field pea regions throughout southern Australia. The novel species were classified on the basis of morphology and phylogenetic analyses of the internal transcribed spacer region and part of the RNA polymerase II subunit B gene region. Three of these species, Nothophoma garlbiwalawarda sp. nov., Nothophoma naiawu sp. nov. and Nothophoma ngayawang sp. nov., were isolated from Senna artemisioides. The other species described here are Epicoccum djirangnandiri sp. nov. from Swainsona galegifolia and Neodidymelliopsis tinkyukuku sp. nov. from Hardenbergia violacea. In addition, we report three new host-pathogen associations in Australia, namely Didymella pinodes on S. artemisioides and Vicia cracca, and D. lethalis on Lathyrus tingitanus. This is also the first report of Didymella prosopidis in Australi
    • …
    corecore