Acetate hemodialysis does not increase the frequency of arrhythmia in hemodialysis patients

Muderrisoglu, Haldun/0000-0002-9635-6313WOS: 000075782700011PubMed: 9754465Arrhythmia is one of the most important causes of mortality in patients on hemodialysis and may develop due to cardiovascular diseases or fluid-electrolyte or acid-base abnormalities. Previous studies have shown that acetate hemodialysis (AHD) increased the frequency of arrythmia. To evaluate the frequency and the causes of arrhythmias during AHD, we studied 33 randomly selected patients (25 male and 8 female, mean age of 45 +/- 18 years) who were under AHD (4 h, 3 times/week, mean duration of HD of 38 +/- 29 months) with the same Cuprophan membranes. All patients underwent a detailed echocardiographic evaluation during the interdialytic period. Twenty-four hours of Holter monitoring was performed starting from the onset of HD. Twelve lead electrocardiography (ECG) was obtained, and venous and arterial blood samples were drawn for serum electrolytes, pH, and arterial blood gas measurements before and after HD. Serum magnesium and potassium levels dropped after AHD (from 2.3 +/- 0.5 to 1.9 +/- 0.3 mEq/L and from 5 +/- 0.7 to 3.4 +/- 0.4 mEq/L respectively, p 0.05). This was also true for supraventricular premature contractions (SVPCs) and supraventricular tachycardia (SVT). Nonsustained ventricular tachycardia was observed in 2 patients during HD and in 1 patient in the interdialytic period. No relation was established between the echocardiographic findings and the frequency of arrhythmia. In our ambulatory electrocardiographic study, the frequencies of VPCs and SVPCs observed during the interdialytic period were only positively correlated with age (r = 0.54, p = 0.013 and r = 0.50, p = 0.010, respectively). No relation was found between the frequency of arrhythmia and the gender of the patients; duration of HD; etiology of kidney disease; or serum Na, K, Ca, iCa, Mg, bicarbonate, or pH levels (p > 0.05). In conclusion, the application of AHD does not increase the frequency of arrhythmia in HD patients as had been shown in previous studies

Coronary flow reserve is preserved in white‐coat hypertension

OBJECTIVES: To assess the possible influence of white‐coat hypertension (WCH) on coronary flow reserve (CFR). METHODS: CFR was measured by means of transthoracic second harmonic Doppler echocardiography in 29 patients with WCH, 32 patients with sustained hypertension and 35 healthy volunteers. RESULTS: CFR was significantly lower in the sustained hypertension group than in the WCH and the control groups, but it was not different between the WCH and the control groups (2.40 (SD 0.54), 2.77 (0.41) and 2.83 (0.60), respectively). CONCLUSION: CFR is preserved in patients with WCH

Research on possible damage caused by recreational activities in Yedigoller National Park

The purpose of this study was to determine possible damage created by recreational activities in Yedigoller (Seven Lakes) National Park and to recommend recreational impact management decisions in order to ensure its sustainable use. Four picnic and camping areas and one control area in the National Park were selected as sampling areas. In order to determine the ecological effects of recreational activities and the pressures on the plant life and the soil, an observation form was used. The study also addressed the stress on the Fagus orientalis trees in all recreation areas near Nazli Lake, Buyuk Lake, and Derin Lake. Findings from the soil analysis indicated that in general, intense human activities in the area had negatively affected both the physical and chemical properties of the soil. As a result of the evaluation of the observation forms, all of the sampling areas in the park were determined to be in poor condition.project titled Research on Possible Damage of Recreational Activities in Yedigoller National ParkThis study was supported by the project titled Research on Possible Damage of Recreational Activities in Yedigoller National Park upon the request of the Nature Conservation and National Parks 9th Regional Directorate of the Bolu National Parks Branch Directorate. We also thank Assoc. Prof. Dr. Hulya Torun for contributing to the measurement of the physiological parameters in the study.WOS:0006745646000022-s2.0-8511080671

Circulating levels of adiponectin, orexin-A, ghrelin and the antioxidant paraoxonase-1 in metabolic syndrome

Aim. Metabolic syndrome (MS) is a disorder consisting of various abnormalities such as dyslipidemia, obesity, hypertension and hyperglycemia. Over the past two decades, the prevalence of MS has greatly increased, and it has become a global health problem. We measured and compared plasma concentrations of adiponectin, orexin-A, ghrelin and the antioxidant paraoxonase-1 (PON1) between patients with metabolic syndrome (MS) and healthy controls