177 research outputs found
Physiological aspects of educational training adaptation of students
20 healthy male and female students of Artsakh State University aged 18-20 years have participated in an experiment to study the mechanisms of training adaptation. Surveys were conducted during the academic semester in 2 stages: the non-examination period (March-April) - Monday and Friday, before and after school and during the examination period (May-June) - before and after the exam. In order to study the impact of mental stress a survey was also conducted among students once they complete mental or intellectual Eysenck test. A psychological testing of students was carried out to identify the level of intelligence (IQ) by Eysenck, personal and situational anxiety by Spielberger and health, activity, mood by SAN (HAM) questionnaire. Basic hemodynamic parameters were measured: heart rate, systolic and diastolic blood pressure. ECG examination was conducted using R.M. Baevsky's cardio-ervalography method. Comparative analysis of the dynamics of the studied parameters showed that the process of adaptation of students to the teaching load is accompanied by periods of decline during non-examination period, more vividly expressed when doing mental or intellectual work, and tension of the studied parameters during the examination period
Applications of p-deficiency and p-largeness
We use Schlage-Puchta's concept of p-deficiency and Lackenby's property of
p-largeness to show that a group having a finite presentation with p-deficiency
greater than 1 is large, which implies that Schlage-Puchta's infinite finitely
generated p-groups are not finitely presented. We also show that for all primes
p at least 7, any group having a presentation of p-deficiency greater than 1 is
Golod-Shafarevich, and has a finite index subgroup which is Golod-Shafarevich
for the remaining primes. We also generalise a result of Grigorchuk on Coxeter
groups to odd primes.Comment: 23 page
An analysis of blood pressure screening of 21Â 112 participants in Armenia: May Measurement Month 2018.
Elevated blood pressure (BP) is a growing burden worldwide and is the leading cause of mortality and disability-adjusted life years all over the world. May Measurement Month (MMM) is a global initiative aimed to raise awareness of high BP and to act as a temporary solution to the lack of screening programmes worldwide. An opportunistic cross-sectional survey of volunteers aged ≥18 was carried out in May to July 2018. Blood pressure measurement, the definition of hypertension (HTN) and statistical analysis followed the standard MMM protocol. The study was conducted in public areas (17 sites in Yerevan and 22 in regions), both indoor and outdoor, as well as in 78 primary care centres. A total of 21 112 individuals were screened during MMM18, of which 20 732 had three BP measurements available. The mean age of screened individuals was 46.2 ± 17.3 years, 57.8% were female. At the time of screening, 26.1% were on antihypertensive medication. After imputation, the percentage of participants with HTN was 38.7%, and 76.7% of them were aware of their high BP. Of participants receiving treatment, 47.1% had a controlled BP. MMM18 was the largest BP screening campaign undertaken in Armenia. We found that the proportion of HTN is substantial in Armenia, which may be a vital contributor to the growing burden of non-communicable diseases. Our results also suggest that untreated HTN is common and when treated still not adequately controlled in Armenia. The current situation, with an insufficient control rate of HTN, must be changed as soon as possible
Axiomatic geometrical optics, Abraham-Minkowski controversy, and photon properties derived classically
By restating geometrical optics within the field-theoretical approach, the
classical concept of a photon (and, more generally, any elementary excitation)
in arbitrary dispersive medium is introduced, and photon properties are
calculated unambiguously. In particular, the canonical and kinetic momenta
carried by a photon, as well as the two corresponding energy-momentum tensors
of a wave, are derived from first principles of Lagrangian mechanics. As an
example application of this formalism, the Abraham-Minkowski controversy
pertaining to the definitions of these quantities is resolved for linear waves
of arbitrary nature, and corrections to the traditional formulas for the photon
kinetic energy-momentum are found. Several other applications of axiomatic
geometrical optics to electromagnetic waves are also presented
May Measurement Month 2017: an analysis of blood pressure screening results in Armenia-Europe
Elevated blood pressure (BP) is a growing burden worldwide, leading to over 10 million deaths each year. May Measurement Month (MMM) is a global initiative aimed at raising awareness of high BP and to act as a temporary solution to the lack of screening programmes worldwide. An opportunistic cross-sectional survey of volunteers aged ≥18 was carried out in May 2017. Blood pressure measurement, the definition of hypertension and statistical analysis followed the standard MMM protocol. The study was conducted in public areas (14 sites in Yerevan and 18 in regions), both indoor and outdoor, as well as in 42 primary care centres. A total of 9199 individuals were screened during MMM17 of which 9186 had three BP measurements available. The mean age of screened individuals was 50 ± 16.7 years, 57.3% was female. At the time of screening 17.9% were on antihypertensive medication. After imputation, a percentage of participants with hypertension was 33.9%, and 52.9% of them were on treatment. Of those treated, 77.0% had uncontrolled BP. MMM17 was the largest BP screening campaign undertaken in Armenia. We found that in Armenia, untreated hypertension is common, as is not adequately treated hypertension
Single-cell multi-omics reveals dyssynchrony of the innate and adaptive immune system in progressive COVID-19.
Dysregulated immune responses against the SARS-CoV-2 virus are instrumental in severe COVID-19. However, the immune signatures associated with immunopathology are poorly understood. Here we use multi-omics single-cell analysis to probe the dynamic immune responses in hospitalized patients with stable or progressive course of COVID-19, explore V(D)J repertoires, and assess the cellular effects of tocilizumab. Coordinated profiling of gene expression and cell lineage protein markers shows that S100
A Search for Technosignatures Around 11,680 Stars with the Green Bank Telescope at 1.15-1.73 GHz
We conducted a search for narrowband radio signals over four observing
sessions in 2020-2023 with the L-band receiver (1.15-1.73 GHz) of the 100 m
diameter Green Bank Telescope. We pointed the telescope in the directions of 62
TESS Objects of Interest, capturing radio emissions from a total of ~11,680
stars and planetary systems in the ~9 arcminute beam of the telescope. All
detections were either automatically rejected or visually inspected and
confirmed to be of anthropogenic nature. In this work, we also quantified the
end-to-end efficiency of radio SETI pipelines with a signal injection and
recovery analysis. The UCLA SETI pipeline recovers 94.0% of the injected
signals over the usable frequency range of the receiver and 98.7% of the
injections when regions of dense RFI are excluded. In another pipeline that
uses incoherent sums of 51 consecutive spectra, the recovery rate is ~15 times
smaller at ~6%. The pipeline efficiency affects calculations of transmitter
prevalence and SETI search volume. Accordingly, we developed an improved Drake
Figure of Merit and a formalism to place upper limits on transmitter prevalence
that take the pipeline efficiency and transmitter duty cycle into account.
Based on our observations, we can state at the 95% confidence level that fewer
than 6.6% of stars within 100 pc host a transmitter that is detectable in our
search (EIRP > 1e13 W). For stars within 20,000 ly, the fraction of stars with
detectable transmitters (EIRP > 5e16 W) is at most 3e-4. Finally, we showed
that the UCLA SETI pipeline natively detects the signals detected with AI
techniques by Ma et al. (2023).Comment: 22 pages, 9 figures, submitted to AJ, revise
Gut Microbiome Dysbiosis in Antibiotic-Treated COVID-19 Patients is Associated with Microbial Translocation and Bacteremia
Although microbial populations in the gut microbiome are associated with COVID-19 severity, a causal impact on patient health has not been established. Here we provide evidence that gut microbiome dysbiosis is associated with translocation of bacteria into the blood during COVID-19, causing life-threatening secondary infections. We first demonstrate SARS-CoV-2 infection induces gut microbiome dysbiosis in mice, which correlated with alterations to Paneth cells and goblet cells, and markers of barrier permeability. Samples collected from 96 COVID-19 patients at two different clinical sites also revealed substantial gut microbiome dysbiosis, including blooms of opportunistic pathogenic bacterial genera known to include antimicrobial-resistant species. Analysis of blood culture results testing for secondary microbial bloodstream infections with paired microbiome data indicates that bacteria may translocate from the gut into the systemic circulation of COVID-19 patients. These results are consistent with a direct role for gut microbiome dysbiosis in enabling dangerous secondary infections during COVID-19
- …