102 research outputs found

    Peter Stuyvesant’s leadership of New Netherland

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    Abstract. My thesis focuses on the director general of New Netherland, Peter Stuyvesant. In my thesis I study in what kind of manner did he lead New Netherland and how was his relationship with the settlers of the colony. To find these answers I compare him to the previous director generals and also to his correspondence with the rulers of Amsterdam. In the thesis I reach the conclusion that Peter Stuyvesant was in fact almost a dictator. He had great amount of power and authority, way more than any of his predecessor. He used this power to rule the colony with an iron fist, and managed to grow the colony and make it quite successful. But because of his dictator like governing style the settlers did not like him. His relationship with the settlers was very rough which lead to the settlers mocking him with a cruel nickname and even protests being lead against him.Tiivistelmä. Tutkielmani keskittyy Uuden Hollannin johtajaan Peter Stuyvesant:iin ja siihen millainen johtaja hän oli. Tutkimuksessa pyrin saamaan vastauksen kysymyksiin: millainen johtaja Stuyvesant oli ja millainen hänen suhteensa siirtokunnan asukkaisiin oli? Tuloksena Peter Stuyvesant oli lähes diktaattori joka johti siirtokuntaa vahvalla otteella ja hänen siirtokuntansa asukkaat vihasivat häntä

    Boosting the Figure Of Merit of LSPR-based refractive index sensing by phase-sensitive measurements

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    Localized surface plasmon resonances possess very interesting properties for a wide variety of sensing applications. In many of the existing applications only the intensity of the reflected or transmitted signals is taken into account, while the phase information is ignored. At the center frequency of a (localized) surface plasmon resonance, the electron cloud makes the transition between in- and out-of-phase oscillation with respect to the incident wave. Here we show that this information can experimentally be extracted by performing phase-sensitive measurements, which result in linewidths that are almost one order of magnitude smaller than those for intensity based measurements. As this phase transition is an intrinsic property of a plasmon resonance, this opens up many possibilities for boosting the figure of merit (FOM) of refractive index sensing by taking into account the phase of the plasmon resonance. We experimentally investigated this for two model systems: randomly distributed gold nanodisks and gold nanorings on top of a continuous gold layer and a dielectric spacer and observed FOM values up to 8.3 and 16.5 for the respective nanoparticles

    Magnetoplasmonic design rules for active magneto-optics

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    Light polarization rotators and non-reciprocal optical isolators are essential building blocks in photonics technology. These macroscopic passive devices are commonly based on magneto-optical Faraday and Kerr polarization rotation. Magnetoplasmonics - the combination of magnetism and plasmonics - is a promising route to bring these devices to the nanoscale. We introduce design rules for highly tunable active magnetoplasmonic elements in which we can tailor the amplitude and sign of the Kerr response over a broad spectral range

    Polarimetric Plasmonic Sensing with Bowtie Nanoantenna Arrays

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    We propose a polarimetric plasmonic biosensor based on bowtie nanoantenna array transducers. Through numerical simulations, based on the finite element method (FEM), we study the phase retardation between the components of light polarized parallel and perpendicular to the major axis of the bowties within the arrays. From a design for high volumetric sensitivity at a wavelength of 780 nm, sensitivities ∼5 rad/RIU is obtained, corresponding to a detection limit of ∼10−7 when using a polarimetric readout platform. Similarly, surface sensitivity of the same array is evaluated by simulating the phase retardation changes induced by the coverage of bioreceptors and analytes of the metallic nanostructures

    Securing the Downside Up: Client and Care Factors Associated with Outcomes of Secure Residential Youth Care

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    Although secure residential care has the potential of reducing young people's behavioral problems, it is often difficult to achieve positive outcomes. Research suggests that there are several common success factors of treatment, of which the client's motivation for treatment and the quality of the therapeutic relationship between clients and therapists might be especially relevant and important in the context of secure residential care. The objective of the present study was to explore the association of these potential success factors with secure residential care outcomes. A repeated measures research design was applied in the study, including a group of adolescents in a secure residential care center that was followed up on three measurements in time. Interviews and questionnaires concerning care outcomes in terms of adolescents' behavior change during care were administered to 22 adolescents and 27 group care workers. Outcomes in terms of adolescents' treatment satisfaction were assessed by the use of questionnaires, which were completed by 51 adolescents. Adolescents reported some positive changes in their treatment motivation, but those who were more likely to be motivated at admission were also more likely to deteriorate in treatment motivation from admission to departure. Treatment satisfaction was associated with better treatment motivation at admission and with a positive adolescent-group care worker relationship. The results suggest that outcomes can be improved by a more explicit treatment focus on improving the adolescent's treatment motivation and the quality of the adolescent-care worker relationship during secure residential care

    Evaluation of an open access echocardiography service in the Netherlands: a mixed methods study of indications, outcomes, patient management and trends

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    Background: In our region (Eastern South Limburg, The Netherlands) an open access echocardiography service started in 2002. It was the first service of this kind in The Netherlands. Our study aims were: (1) to evaluate demand for the service, participation, indications, echocardiography outcomes, and management by the general practitioner (GP); (2) to analyse changes in indications and outcomes over the years. Methods: (1) Data from GP request forms, echocardiography reports and a retrospective GP questionnaire on management (response rate 83%) of 625 consecutive patients (Dec. 2002-March 2007) were analysed cross-sectionally. (2) For the analysis of changes over the years, data from GP request forms and echocardiography reports of the first and last 250 patients that visited the service between Dec. 2002 and Feb. 2008 (n = 1001) were compared. Results: The echocardiography service was used by 81% of the regional GPs. On average, a GP referred one patient per year to the service. Intended indications for the service were dyspnoea (32%), cardiac murmur (59%), and peripheral oedema (17%). Of the other indications (22%), one-third was for evaluation of suspected left ventricular hypertrophy (LVH). Expected outcomes were left ventricular dysfunction (LVD) (43%, predominantly diastolic) and valve disease (25%). We also found a high proportion of LVH (50%). Only 24% of all echocardiograms showed no relevant disease. The GP followed the cardiologist's advice to refer the patient for further evaluation in 71%. In recent patients, more echocardiography requests were done for 'cardiac murmur' and 'other' indications, but less for 'dyspnoea'. The proportions of patients with LVD, LVH and valve disease decreased and the proportion of patients with no relevant disease increased. The number of advices by the cardiologists increased. Conclusion: Overall, GPs used the open access echocardiography service efficiently (i. e. with a high chance of finding relevant pathology), but efficiency decreased slightly over the years. To meet the needs of the GPs, indications might be widened with 'suspicion LVH'. Further specification of the indications for open access echocardiography-by defining a stepwise diagnostic approach including ECG and (NT-pro)BNP-might improve the service

    Baseline characteristics of patients in the reduction of events with darbepoetin alfa in heart failure trial (RED-HF)

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    <p>Aims: This report describes the baseline characteristics of patients in the Reduction of Events with Darbepoetin alfa in Heart Failure trial (RED-HF) which is testing the hypothesis that anaemia correction with darbepoetin alfa will reduce the composite endpoint of death from any cause or hospital admission for worsening heart failure, and improve other outcomes.</p> <p>Methods and results: Key demographic, clinical, and laboratory findings, along with baseline treatment, are reported and compared with those of patients in other recent clinical trials in heart failure. Compared with other recent trials, RED-HF enrolled more elderly [mean age 70 (SD 11.4) years], female (41%), and black (9%) patients. RED-HF patients more often had diabetes (46%) and renal impairment (72% had an estimated glomerular filtration rate <60 mL/min/1.73 m2). Patients in RED-HF had heart failure of longer duration [5.3 (5.4) years], worse NYHA class (35% II, 63% III, and 2% IV), and more signs of congestion. Mean EF was 30% (6.8%). RED-HF patients were well treated at randomization, and pharmacological therapy at baseline was broadly similar to that of other recent trials, taking account of study-specific inclusion/exclusion criteria. Median (interquartile range) haemoglobin at baseline was 112 (106–117) g/L.</p> <p>Conclusion: The anaemic patients enrolled in RED-HF were older, moderately to markedly symptomatic, and had extensive co-morbidity.</p&gt

    Nathan Hilversum (Amersfoort 1873-1959) : volharding en verdriet van een joodse ondernemer

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    Nathan Hilversum was een joodse Amersfoortse koopman/handelaar. Hij was in 1924 medeoprichter van de eerste stadsbusdienst, die hij tot 1930 exploiteerde. Deze ondernemer was ook maatschappelijk actief in Amersfoort. De Tweede Wereldoorlog bepaalt sterk zijn geschiedenis. Bijna zijn hele familie is omgebracht door de Duitsers, waaronder zijn zes zonen. Hij en zijn vrouw overleefden de oorlog, ondergedoken in Amsterda

    Drie Melmen aan de Eem? : een kritiek na veertig jaren

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    In het verleden bestonden er meerdere 'melmen' (natuurlijke ophogingen en aanspoeling van zand) aan de Soester kant van de Eem. In de literatuur bestaat verschil van mening over het aantal melmen. In dit artikel wordt de discussie afgesloten
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