562 research outputs found
On Vector Bundles of Finite Order
We study growth of holomorphic vector bundles E over smooth affine manifolds.
We define Finsler metrics of finite order on E by estimates on the holomorphic
bisectional curvature. These estimates are very similar to the ones used by
Griffiths and Cornalba to define Hermitian metrics of finite order. We then
generalize the Vanishing Theorem of Griffiths and Cornalba to the Finsler
context. We develop a value distribution theory for holomorphic maps from the
projectivization of E to projective space. We show that the projectivization of
E can be immersed into a projective space of sufficiently large dimension via a
map of finite order.Comment: version 2 has some typos corrected; to appear in Manuscripta
Mathematic
Inverse problem and Bertrand's theorem
The Bertrand's theorem can be formulated as the solution of an inverse
problem for a classical unidimensional motion. We show that the solutions of
these problems, if restricted to a given class, can be obtained by solving a
numerical equation. This permit a particulary compact and elegant proof of
Bertrand's theorem.Comment: 11 pages, 3 figure
Effects of nanoparticles on murine macrophages
Metallic nanoparticles are more and more widely used in an increasing number
of applications. Consequently, they are more and more present in the
environment, and the risk that they may represent for human health must be
evaluated. This requires to increase our knowledge of the cellular responses to
nanoparticles. In this context, macrophages appear as an attractive system.
They play a major role in eliminating foreign matter, e.g. pathogens or
infectious agents, by phagocytosis and inflammatory responses, and are thus
highly likely to react to nanoparticles. We have decided to study their
responses to nanoparticles by a combination of classical and wide-scope
approaches such as proteomics. The long term goal of this study is the better
understanding of the responses of macrophages to nanoparticles, and thus to
help to assess their possible impact on human health. We chose as a model
system bone marrow-derived macrophages and studied the effect of commonly used
nanoparticles such as TiO2 and Cu. Classical responses of macrophage were
characterized and proteomic approaches based on 2D gels of whole cell extracts
were used. Preliminary proteomic data resulting from whole cell extracts showed
different effects for TiO2-NPs and Cu-NPs. Modifications of the expression of
several proteins involved in different pathways such as, for example, signal
transduction, endosome-lysosome pathway, Krebs cycle, oxidative stress response
have been underscored. These first results validate our proteomics approach and
open a new wide field of investigation for NPs impact on macrophagesComment: Nanosafe2010: International Conference on Safe Production and Use of
Nanomaterials 16-18 November 2010, Grenoble, France, Grenoble : France (2010
Polya's inequalities, global uniform integrability and the size of plurisubharmonic lemniscates
First we prove a new inequality comparing uniformly the relative volume of a
Borel subset with respect to any given complex euclidean ball \B \sub \C^n
with its relative logarithmic capacity in \C^n with respect to the same ball
\B.
An analoguous comparison inequality for Borel subsets of euclidean balls of
any generic real subspace of \C^n is also proved.
Then we give several interesting applications of these inequalities.
First we obtain sharp uniform estimates on the relative size of \psh
lemniscates associated to the Lelong class of \psh functions of logarithmic
singularities at infinity on \C^n as well as the Cegrell class of
\psh functions of bounded Monge-Amp\`ere mass on a hyperconvex domain \W
\Sub \C^n.
Then we also deduce new results on the global behaviour of both the Lelong
class and the Cegrell class of \psh functions.Comment: 25 page
Population-based evaluation of a suggested anatomic and clinical classification of congenital heart defects based on the International Paediatric and Congenital Cardiac Code
<p>Abstract</p> <p>Background</p> <p>Classification of the overall spectrum of congenital heart defects (CHD) has always been challenging, in part because of the diversity of the cardiac phenotypes, but also because of the oft-complex associations. The purpose of our study was to establish a comprehensive and easy-to-use classification of CHD for clinical and epidemiological studies based on the long list of the International Paediatric and Congenital Cardiac Code (IPCCC).</p> <p>Methods</p> <p>We coded each individual malformation using six-digit codes from the long list of IPCCC. We then regrouped all lesions into 10 categories and 23 subcategories according to a multi-dimensional approach encompassing anatomic, diagnostic and therapeutic criteria. This anatomic and clinical classification of congenital heart disease (ACC-CHD) was then applied to data acquired from a population-based cohort of patients with CHD in France, made up of 2867 cases (82% live births, 1.8% stillbirths and 16.2% pregnancy terminations).</p> <p>Results</p> <p>The majority of cases (79.5%) could be identified with a single IPCCC code. The category "Heterotaxy, including isomerism and mirror-imagery" was the only one that typically required more than one code for identification of cases. The two largest categories were "ventricular septal defects" (52%) and "anomalies of the outflow tracts and arterial valves" (20% of cases).</p> <p>Conclusion</p> <p>Our proposed classification is not new, but rather a regrouping of the known spectrum of CHD into a manageable number of categories based on anatomic and clinical criteria. The classification is designed to use the code numbers of the long list of IPCCC but can accommodate ICD-10 codes. Its exhaustiveness, simplicity, and anatomic basis make it useful for clinical and epidemiologic studies, including those aimed at assessment of risk factors and outcomes.</p
Discrete complex analysis on planar quad-graphs
We develop a linear theory of discrete complex analysis on general
quad-graphs, continuing and extending previous work of Duffin, Mercat, Kenyon,
Chelkak and Smirnov on discrete complex analysis on rhombic quad-graphs. Our
approach based on the medial graph yields more instructive proofs of discrete
analogs of several classical theorems and even new results. We provide discrete
counterparts of fundamental concepts in complex analysis such as holomorphic
functions, derivatives, the Laplacian, and exterior calculus. Also, we discuss
discrete versions of important basic theorems such as Green's identities and
Cauchy's integral formulae. For the first time, we discretize Green's first
identity and Cauchy's integral formula for the derivative of a holomorphic
function. In this paper, we focus on planar quad-graphs, but we would like to
mention that many notions and theorems can be adapted to discrete Riemann
surfaces in a straightforward way.
In the case of planar parallelogram-graphs with bounded interior angles and
bounded ratio of side lengths, we construct a discrete Green's function and
discrete Cauchy's kernels with asymptotics comparable to the smooth case.
Further restricting to the integer lattice of a two-dimensional skew coordinate
system yields appropriate discrete Cauchy's integral formulae for higher order
derivatives.Comment: 49 pages, 8 figure
Forced Stratified Turbulence: Successive Transitions with Reynolds Number
Numerical simulations are made for forced turbulence at a sequence of
increasing values of Reynolds number, R, keeping fixed a strongly stable,
volume-mean density stratification. At smaller values of R, the turbulent
velocity is mainly horizontal, and the momentum balance is approximately
cyclostrophic and hydrostatic. This is a regime dominated by so-called pancake
vortices, with only a weak excitation of internal gravity waves and large
values of the local Richardson number, Ri, everywhere. At higher values of R
there are successive transitions to (a) overturning motions with local
reversals in the density stratification and small or negative values of Ri; (b)
growth of a horizontally uniform vertical shear flow component; and (c) growth
of a large-scale vertical flow component. Throughout these transitions, pancake
vortices continue to dominate the large-scale part of the turbulence, and the
gravity wave component remains weak except at small scales.Comment: 8 pages, 5 figures (submitted to Phys. Rev. E
The Archaeology of the Siege of Fort William, 1746
In August and September 2007, the Centre for Battlefield Archaeology and Glasgow University Archaeological Research Division (GUARD) conducted a programme of archaeological investigation of the remains of the old fort at Fort William and part of The Parade in the town of Fort William on the west coast of Scotland. The fieldwork involved geophysical survey at the fort and The Parade, followed by trial excavation of anomalies. Trial trenches at The Parade exposed several rich midden deposits and material providing evidence for the burning of the town of Maryburgh, as suggested in contemporary accounts in 1746. The results at the fort were not so positive, as most traces of the garrison were removed in the 19th and 20th centuries through its use as a railway yard; however, a trench outside the fort suggests survival of midden deposits pre-dating this period of destruction. This part-Heritage Lottery assisted project was a Highland 2007 initiative supported by Lochaber Community Fund and Highland Council, and included active participation on the part of the local community, including school groups and metal detectorists
About curvature, conformal metrics and warped products
We consider the curvature of a family of warped products of two
pseduo-Riemannian manifolds and furnished with metrics of
the form and, in particular, of the type , where are smooth
functions and is a real parameter. We obtain suitable expressions for the
Ricci tensor and scalar curvature of such products that allow us to establish
results about the existence of Einstein or constant scalar curvature structures
in these categories. If is Riemannian, the latter question involves
nonlinear elliptic partial differential equations with concave-convex
nonlinearities and singular partial differential equations of the
Lichnerowicz-York type among others.Comment: 32 pages, 3 figure
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