Processing and Technology of Fruits and Vegetables, 1960

Tomato Variety Evaluation for Processing, 1961 / W. A. Gould, J. R. Geisman and Wade Schulte -- Evaluation of Sweet Corn Varieties for Processing / J. R. Geisman and W. A. Gould -- Small Fruit Variety Evaluation Studies for Freezing / D. R. Davis and H. L. Stammer -- Evaluation of Apples for Processing. I. Fruit Juice Blends / D. R. Davis and H. L. Stammer -- Evaluation of Apples for Processing. II. Canned Apple Slices / D. R. Davis and H. L. Stammer -- Evaluation of Apples for Processing. III. Frozen Apple Slices / D. R. Davis and H. L. Stammer -- Evaluation of Apples for Processing. IV. Frozen Fruit Pies / D. R. Davis and H. L. Stammer -- A Study of Several Varieties of Pumpkin and Squash for Canning and Freezing for Use in Pies / Robert H. Clayton, J. R. Geisman and W. A. Gould -- Factors Effecting the Consistency of Cream Style Corn / D. R. Davis and W. A. Gould -- The Objective Measurement of Tomato Juice Consistency / Robert Kluter and W. A. Gould -- A Method for the Detection of Drosophila Fly Eggs and Larvae in Tomato Products / J. R. Geisman and Winston D. Bash -- A Chemical Study of Flavor and Flavor Substances in Tomatoes / John Hal Johnson and W. A. Gould -- Tannin Content Effects Grape Juice Quality / D. R. Davis and H. L. Stammer -- pH Survey for Tomatoes in Ohio / W. D. Bash -- Flavor Studies with Sauerkraut / J. R. Geisman, S. S. Verma and W. A. Gould -- The Effect of Fill Weight on Drained Weight of Canned Tomatoes / Wade A. Schulte and W. A. Gould -- A New Method for the Manufacture of Apple Sirup / M. P. Baldauf, D. R. Davis and H. L. Stammer -- Studies on Color Retention in Canned R.T.P. Cherries / D. R. Davis and H. L. Stammer -- Clumping Studies in Canned Blueberries / D. R. Davis and H. L. Stammer -- Infra-red Peeling Studies. I. Apples. / L. Lafferty and W. A. Gould -- Infra-red Peeling Studies. II. Tomatoes. / W. A. Gould, Richard Leiss and Donall Streets -- The Effect of Water Holding Times and Temperatures on Quality of Tomatoes / Richard Leiss, Ernest Anderson and W. A. Gould -- Quality Attributes of Sweet Potatoes - Glass Packed / Donald A. Giesser and W. A. Gould -- A Study of Some of the Factors Effecting the Efficiency of Washing of Fruits and Vegetables. I. Tomatoes / W. A. Gould and J. R. Geisman -- A Study of Some of the Factors Effecting the Efficiency of Washing of Fruits and Vegetables. II. Sweet Corn / J. R. Geisman and W. A. Gould -- A Study of Alpha-keto Acids, Amino Acids, and Citric Acid in Eight Tomato Varieties, and Their Changes During Processing / Mokhtar M. Hamdy and W. A. Goul

Large Scale Association Analysis of Novel Genetic Loci for Coronary Artery Disease

Background-Combined analysis of 2 genome-wide association studies in cases enriched for family history recently identified 7 loci (on 1p13.3, 1q41, 2q36.3, 6q25.1, 9p21, 10q11.21, and 15q22.33) that may affect risk of coronary artery disease (CAD). Apart from the 9p21 locus, the other loci await substantive replication. Furthermore, the effect of these loci on CAD risk in a broader range of individuals remains to be determined.Methods and Results-We undertook association analysis of single nucleotide polymorphisms at each locus with CAD risk in 11 550 cases and 11 205 controls from 9 European studies. The 9p21.3 locus showed unequivocal association (rs1333049, combined odds ratio [OR]=1.20, 95% CI [1.16 to 1.25], probability value=2.81x10(-21)). We also confirmed association signals at 1p13.3 (rs599839, OR=1.13 [1.08 to 1.19], P=1.44x10(-7)), 1q41 (rs3008621, OR=1.10 [1.04 to 1.17], P=1.02x10(-3)), and 10q11.21 (rs501120, OR=1.11 [1.05 to 1.18], P=4.34x10(-4)). The associations with 6q25.1 (rs6922269, P=0.020) and 2q36.3 (rs2943634, P=0.032) were borderline and not statistically significant after correction for multiple testing. The 15q22.33 locus did not replicate. The 10q11.21 locus showed a possible sex interaction (P = 0.015), with a significant effect in women (OR=1.29 [1.15 to 1.45], P=1.86x10(-5)) but not men (OR=1.03 [0.96 to 1.11], P=0.387). There were no other strong interactions of any of the loci with other traditional risk factors. The loci at 9p21, 1p13.3, 2q36.3, and 10q11.21 acted independently and cumulatively increased CAD risk by 15% (12% to 18%), per additional risk allele. ConclusionsThe findings provide strong evidence for association between at least 4 genetic loci and CAD risk. Cumulatively, these novel loci have a significant impact on risk of CAD at least in European populations. (Arterioscler Thromb Vasc Biol. 2009; 29: 774-780.

Electromagnetic transduction therapy and shockwave therapy in 86 patients with rotator cuff tendinopathy: A prospective randomized controlled trial

Rotator cuff (RC) tendinopathy is the most common cause of shoulder pain. The effectiveness of electromagnetic transduction therapy (EMTT), a high energetic pulsed electromagnetic field therapy in this field has not been tested yet in combination with extracorporeal shock wave therapy (ESWT).A total of 86 patients with RC tendinopathy were randomized to undergo three sessions of ESWT in combination with 8 sessions of EMTT or sham-EMTT. Both intervention groups experienced significant and clinical relevant decrease of pain at all follow-up visits, and the functionality of the shoulder evaluated by the Constant Murley score increased significantly as well. The combination of EMTT+ESWT produced significantly greater pain reduction in the visual analogue scale compared to ESWT with sham-EMTT after 24weeks, during which the Constant Murley score improved significantly when the combination of ESWT and EMTT was employed.In patients with RC tendinopathy, electromagnetic transduction therapy combined with extracorporeal shock wave therapy significantly improves pain and function compared to ESWT with sham-EMTT

Expression of the protective antigen of Bacillus anthracis by Lactobacillus casei: towards the development of an oral vaccine against anthrax

Bacillus anthracis is the causative organism of the disease anthrax. The ability of the organism to form resistant spores and infect via the aerosol route has led to it being considered as a potential biological warfare agent. The current available human vaccines are far from ideal, they are expensive to produce, require repeated doses and may invoke transient side-effects in some individuals. There is also evidence to suggest that they may not give full protection against all strains of B. anthracis. A new generation of anthrax vaccine is therefore needed. The use of Lactobacillus as a vector for expression of heterologous proteins from pathogens supplies us with a safe system, which can be given orally. Lactobacilli are commensals of the gut, generally regarded as safe and have intrinsic adjuvanticity. Oral vaccines may stimulate the mucosol immune system to produce local IgA responses in addition to systemic responses. These vectors are delivered at the mucosal surface, the site where the infection actually occurs and where the first line of defence lies. The gene encoding the protective antigen (PA) of B. anthracis, an immunogenic non-toxic component of the two toxins produced, is being cloned into different homologous vectors and subsequently transformed to various Lactobacillus strains. High intracellular expression levels for the PA in Lact. casei were achieved. Mucosal antigen presentation and humoral and cellular immune responses following immunization with transformants expressing PA in various ways (intracellular, surface-anchored and extracellular) are being studied