292 research outputs found

    A systematic review and meta-analysis of qigong for the fibromyalgia syndrome

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    Objectives. The fibromyalgia syndrome (FMS) is a chronic condition with only few evidence-based complementary and alternative therapies available. This paper presents a systematic review and meta-analysis of the effectiveness of Qigong for fibromyalgia syndrome. Methods. The PubMed/MEDLINE, Cochrane Library, Embase, PsycINFO, and Cambase databases were screened in December 2012 to identify randomized controlled trials comparing Qigong to control interventions. Major outcome measures were pain and quality of life; and secondary outcomes included sleep quality, fatigue, depression, and safety. Standardized mean differences (SMD) and 95% confidence intervals were calculated. Results. Seven trials were located with a total of 395 FMS patients. Analyses revealed low quality evidence for short-term improvement of pain, quality of life, and sleep quality and very low quality evidence for improvement of fatigue after Qigong for FMS, when compared to usual care. No evidence was found for superiority of Qigong compared to active treatments. No serious adverse events were reported. Discussion. This systematic review found that Qigong may be a useful approach for FMS patients. According to the quality of evidence, only a weak recommendation for Qigong can be made at this point. Further high quality RCTs are required for the conclusive judgment of its long-term effects. © 2013 Romy Lauche et al

    Investigating potential transferability of place-based research in land system science

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    Much of our knowledge about land use and ecosystem services in interrelated social-ecological systems is derived from place-based research. While local and regional case studies provide valuable insights, it is often unclear how relevant this research is beyond the study areas. Drawing generalized conclusions about practical solutions to land management from local observations and formulating hypotheses applicable to other places in the world requires that we identify patterns of land systems that are similar to those represented by the case study. Here, we utilize the previously developed concept of land system archetypes to investigate potential transferability of research from twelve regional projects implemented in a large joint research framework that focus on issues of sustainable land management across four continents. For each project, we characterize its project archetype, i.e. the unique land system based on a synthesis of more than 30 datasets of land-use intensity, environmental conditions and socioeconomic indicators. We estimate the transferability potential of project research by calculating the statistical similarity of locations across the world to the project archetype, assuming higher transferability potentials in locations with similar land system characteristics. Results show that areas with high transferability potentials are typically clustered around project sites but for some case studies can be found in regions that are geographically distant, especially when values of considered variables are close to the global mean or where the project archetype is driven by large-scale environmental or socioeconomic conditions. Using specific examples from the local case studies, we highlight the merit of our approach and discuss the differences between local realities and information captured in global datasets. The proposed method provides a blueprint for large research programs to assess potential transferability of place-based studies to other geographical areas and to indicate possible gaps in research efforts

    The roles and contributions of Biodiversity Observation Networks (BONs) in better tracking progress to 2020 biodiversity targets: a European case study

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    The Aichi Biodiversity Targets of the United Nations’ Strategic Plan for Biodiversity set ambitious goals for protecting biodiversity from further decline. Increased efforts are urgently needed to achieve these targets by 2020. The availability of comprehensive, sound and up-to-date biodiversity data is a key requirement to implement policies, strategies and actions to address biodiversity loss, monitor progress towards biodiversity targets, as well as to assess the current status and future trends of biodiversity. Key gaps, however, remain in our knowledge of biodiversity and associated ecosystem services. These are mostly a result of barriers preventing existing data from being discoverable, accessible and digestible. In this paper, we describe what regional Biodiversity Observation Networks (BONs) can do to address these barriers using the European Biodiversity Observation Network (EU BON) as an example. We conclude that there is an urgent need for a paradigm shift in how biodiversity data are collected, stored, shared and streamlined in order to tackle the many sustainable development challenges ahead. We need a shift towards an integrative biodiversity information framework, starting from collection to the final interpretation and packaging of data. This is a major objective of the EU BON project, towards which progress is being made

    Connected Green function approach to ground state symmetry breaking in Φ1+14\Phi^4_{1+1}-theory

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    Using the cluster expansions for n-point Green functions we derive a closed set of dynamical equations of motion for connected equal-time Green functions by neglecting all connected functions higher than 4th4^{th} order for the λΦ4\lambda \Phi^4-theory in 1+11+1 dimensions. We apply the equations to the investigation of spontaneous ground state symmetry breaking, i.e. to the evaluation of the effective potential at temperature T=0T=0. Within our momentum space discretization we obtain a second order phase transition (in agreement with the Simon-Griffith theorem) and a critical coupling of λcrit/4m2=2.446\lambda_{crit}/4m^2=2.446 as compared to a first order phase transition and λcrit/4m2=2.568\lambda_{crit}/4m^2=2.568 from the Gaussian effective potential approach.Comment: 25 Revtex pages, 5 figures available via fpt from the directory ugi-94-11 of [email protected] as one postscript file (there was a bug in our calculations, all numerical results and figures have changed significantly), ugi-94-1

    Cluster Expansion Approach to the Effective Potential in Φ2+14\Phi^4_{2+1}-Theory

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    We apply a truncated set of dynamical equations of motion for connected equal-time Green functions up to the 4-point level to the investigation of spontaneous ground state symmetry breaking in Φ2+14\Phi^4_{2+1} quantum field theory. Within our momentum space discretization we obtain a second order phase transition as soon as the connected 3-point function is included. However, an additional inclusion of the connected 4-point function still shows a significant influence on the shape of the effective potential and the critical coupling.Comment: 1 compressed uuencoded postscript file with 5 figures included, 21 page

    Ultrafast optically induced spin transfer in ferromagnetic alloys

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    The vision of using light to manipulate electronic and spin excitations in materials on their fundamental time and length scales requires new approaches in experiment and theory to observe and understand these excitations. The ultimate speed limit for all-optical manipulation requires control schemes for which the electronic or magnetic subsystems of the materials are coherently manipulated on the time scale of the laser excitation pulse. In our work, we provide experimental evidence of such a direct, ultrafast, and coherent spin transfer between two magnetic subsystems of an alloy of Fe and Ni. Our experimental findings are fully supported by time-dependent density functional theory simulations and, hence, suggest the possibility of coherently controlling spin dynamics on subfemtosecond time scales, i.e., the birth of the research area of attomagnetism

    Systematic review with meta-analysis: cytokines in fibromyalgia syndrome

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    <p>Abstract</p> <p>Background</p> <p>To perform a systematic review and meta-analysis on cytokine levels in patients with fibromyalgia syndrome (FMS).</p> <p>Methods</p> <p>Through December 2010 we systematically reviewed the databases PubMed, MEDLINE, and PsycINFO and screened the reference lists of 22 review articles for suitable original articles. Original articles investigating cytokines in patients with FMS were included. Data were extracted by two independent authors. Differences of the cytokine levels of FMS patients and controls were summarized by standardized mean differences (SMD) using a random effects model. Study quality was assessed applying methodological scores: modified Center of Evidence Based Medicine, Newcastle-Ottawa-Scale, and WĂĽrzburg Methodological Quality Score.</p> <p>Results</p> <p>Twenty-five articles were included investigating 1255 FMS patients and 800 healthy controls. Data of 13/25 studies entered meta-analysis. The overall methodological quality of studies was low. The results of the majority of studies were not comparable because methods, investigated material, and investigated target cytokines differed. Systematic review of the selected 25 articles revealed that FMS patients had higher serum levels of interleukin (IL)-1 receptor antagonist, IL-6, and IL-8, and higher plasma levels of IL-8. Meta-analysis of eligible studies showed that FMS patients had higher plasma IL-6 levels compared to controls (SMD = -0.34 [-0.64, -0.03] 95% CI; p = 0.03). The majority of investigated cytokines were not different between patients and controls.</p> <p>Conclusions</p> <p>The pathophysiological role of cytokines in FMS is still unclear. Studies of higher quality and with higher numbers of subjects are needed.</p

    Ultrafast optically induced spin transfer in ferromagnetic alloys

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    The vision of using light to manipulate electronic and spin excitations in materials on their fundamental time and length scales requires new approaches in experiment and theory to observe and understand these excitations. The ultimate speed limit for all-optical manipulation requires control schemes for which the electronic or magnetic subsystems of the materials are coherently manipulated on the time scale of the laser excitation pulse. In our work, we provide experimental evidence of such a direct, ultrafast, and coherent spin transfer between two magnetic subsystems of an alloy of Fe and Ni. Our experimental findings are fully supported by time-dependent density functional theory simulations and, hence, suggest the possibility of coherently controlling spin dynamics on subfemtosecond time scales, i.e., the birth of the research area of attomagnetism
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