317 research outputs found
An atom fiber for guiding cold neutral atoms
We present an omnidirectional matter wave guide on an atom chip. The
rotational symmetry of the guide is maintained by a combination of two current
carrying wires and a bias field pointing perpendicular to the chip surface. We
demonstrate guiding of thermal atoms around more than two complete turns along
a spiral shaped 25mm long curved path (curve radii down to 200m) at
various atom--surface distances (35-450m). An extension of the scheme for
the guiding of Bose-Einstein condensates is outlined
Self-Control in Cyberspace: Applying Dual Systems Theory to a Review of Digital Self-Control Tools
Many people struggle to control their use of digital devices. However, our
understanding of the design mechanisms that support user self-control remains
limited. In this paper, we make two contributions to HCI research in this
space: first, we analyse 367 apps and browser extensions from the Google Play,
Chrome Web, and Apple App stores to identify common core design features and
intervention strategies afforded by current tools for digital self-control.
Second, we adapt and apply an integrative dual systems model of self-regulation
as a framework for organising and evaluating the design features found. Our
analysis aims to help the design of better tools in two ways: (i) by
identifying how, through a well-established model of self-regulation, current
tools overlap and differ in how they support self-control; and (ii) by using
the model to reveal underexplored cognitive mechanisms that could aid the
design of new tools.Comment: 11.5 pages (excl. references), 6 figures, 1 tabl
Feasibility of detecting single atoms using photonic bandgap cavities
We propose an atom-cavity chip that combines laser cooling and trapping of
neutral atoms with magnetic microtraps and waveguides to deliver a cold atom to
the mode of a fiber taper coupled photonic bandgap (PBG) cavity. The
feasibility of this device for detecting single atoms is analyzed using both a
semi-classical treatment and an unconditional master equation approach.
Single-atom detection seems achievable in an initial experiment involving the
non-deterministic delivery of weakly trapped atoms into the mode of the PBG
cavity.Comment: 11 pages, 5 figure
Determination of the Carrier-Envelope Phase of Few-Cycle Laser Pulses with Terahertz-Emission Spectroscopy
The availability of few-cycle optical pulses opens a window to physical
phenomena occurring on the attosecond time scale. In order to take full
advantage of such pulses, it is crucial to measure and stabilise their
carrier-envelope (CE) phase, i.e., the phase difference between the carrier
wave and the envelope function. We introduce a novel approach to determine the
CE phase by down-conversion of the laser light to the terahertz (THz) frequency
range via plasma generation in ambient air, an isotropic medium where optical
rectification (down-conversion) in the forward direction is only possible if
the inversion symmetry is broken by electrical or optical means. We show that
few-cycle pulses directly produce a spatial charge asymmetry in the plasma. The
asymmetry, associated with THz emission, depends on the CE phase, which allows
for a determination of the phase by measurement of the amplitude and polarity
of the THz pulse
Refining Kidney Survival in 383 Genetically Characterized Patients With Nephronophthisis
Introduction: Nephronophthisis (NPH) comprises a group of rare disorders accounting for up to 10% of end-stage kidney disease (ESKD) in children. Prediction of kidney prognosis poses a major challenge. We assessed differences in kidney survival, impact of variant type, and the association of clinical characteristics with declining kidney function. Methods: Data was obtained from 3 independent sources, namely the network for early onset cystic kidney diseases clinical registry (n = 105), an online survey sent out to the European Reference Network for Rare Kidney Diseases (n = 60), and a literature search (n = 218). Results: A total of 383 individuals were available for analysis: 116 NPHP1, 101 NPHP3, 81 NPHP4 and 85 NPHP11/TMEM67 patients. Kidney survival differed between the 4 cohorts with a highly variable median age at onset of ESKD as follows: NPHP3, 4.0 years (interquartile range 0.3–12.0); NPHP1, 13.5 years (interquartile range 10.5–16.5); NPHP4, 16.0 years (interquartile range 11.0–25.0); and NPHP11/TMEM67, 19.0 years (interquartile range 8.7–28.0). Kidney survival was significantly associated with the underlying variant type for NPHP1, NPHP3, and NPHP4. Multivariate analysis for the NPHP1 cohort revealed growth retardation (hazard ratio 3.5) and angiotensin-converting enzyme inhibitor (ACEI) treatment (hazard ratio 2.8) as 2 independent factors associated with an earlier onset of ESKD, whereas arterial hypertension was linked to an accelerated glomerular filtration rate (GFR) decline. Conclusion: The presented data will enable clinicians to better estimate kidney prognosis of distinct patients with NPH and thereby allow personalized counseling
Erwartungsbildung über den Wahlausgang und ihr Einfluss auf die Wahlentscheidung
Erwartungen über den Wahlausgang haben einen festen Platz sowohl in Rational-Choice-Theorien des Wählerverhaltens als auch in stärker sozialpsychologisch orientierten Ansätzen. Die Bildung von Erwartungen und ihr Einfluss auf die Wahlentscheidung ist dabei jedoch ein noch relativ unerforschtes Gebiet. In diesem Beitrag werden anhand von Wahlstudien für Belgien, Österreich und Deutschland verschiedene Fragen der Erwartungsbildung und ihrer Auswirkungen untersucht. Zunächst wird die Qualität der Gesamterwartungen analysiert und verschiedene Faktoren identifiziert, die einen systematischen Einfluss auf die Erwartungsbildung haben. Im zweiten Schritt wenden wir uns den Einzelerwartungen über verschiedene Parteien und Koalitionen zu und finden eine moderate Verzerrung zugunsten der präferierten Parteien und Koalitionen. Dabei kann gezeigt werden, dass der Effekt des Wunschdenkens mit dem politischen Wissen und dem Bildungsgrad abnimmt. Schließlich werden in einem letzten Schritt zwei unterschiedliche Logiken für die Auswirkungen von Erwartungen getestet, das rationale Kalkül des koalitionsstrategischen Wählens zur Vermeidung der Stimmenvergeudung sowie der sozialpsychologisch begründete Bandwagon-Effekt. Das Ausmaß an politischem Wissen scheint dabei eine zentrale vermittelnde Variable zwischen den beiden Logiken zu sein
A risk-based approach to cumulative effect assessments for marine management
Marine ecosystems are increasingly threatened by the cumulative effects of multiple human pressures. Cumulative effect assessments (CEAs) are needed to inform environmental policy and guide ecosystem-based management. Yet, CEAs are inherently complex and seldom linked to real-world management processes. Therefore we propose entrenching CEAs in a risk management process, comprising the steps of risk identification, risk analysis and risk evaluation. We provide guidance to operationalize a risk-based approach to CEAs by describing for each step guiding principles and desired outcomes, scientific challenges and practical solutions. We reviewed the treatment of uncertainty in CEAs and the contribution of different tools and data sources to the implementation of a risk based approach to CEAs. We show that a risk-based approach to CEAs decreases complexity, allows for the transparent treatment of uncertainty and streamlines the uptake of scientific outcomes into the science-policy interface. Hence, its adoption can help bridging the gap between science and decision-making in ecosystem-based management
Metal Bioavailability in the Sava River Water
Metals present one of the major contamination problems for freshwater systems, such as the Sava River, due to their high toxicity, persistence, and tendency to accumulate in sediment and living organisms. The comprehensive assessment of the metal bioavailability in the Sava River encompassed the analyses of dissolved and DGT-labile metal species of nine metals (Cd, Co, Cr, Cu, Fe, Mn, Ni, Pb, and Zn) in the river water, as well as the evaluation of the accumulation of five metals (Cd, Cu, Fe, Mn, and Zn) in three organs (liver, gills, and gastrointestinal tissue) of the bioindicator organism, fish species European chub (Squalius cephalus L.).This survey was conducted mainly during the year 2006, in two sampling campaigns, in April/May and September, as periods representative for chub spawning and post-spawning. Additionally, metal concentrations were determined in the intestinal parasites acanthocephalans, which are known for their high affinity for metal accumulation. Metallothionein concentrations were also determined in three chub organs, as a commonly applied biomarker of metal exposure. Based on the metal concentrations in the river water, the Sava River was defined as weakly contaminated and mainly comparable with unpolluted rivers, which enabled the analyses of physiological variability of metal and metallothionein concentrations in the chub organs, as well as the establishment of their constitutive levels
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