173 research outputs found
First Observation of Self-Amplified Spontaneous Emission in a Free-Electron Laser at 109 nm Wavelength
We present the first observation of Self-Amplified Spontaneous Emission
(SASE) in a free-electron laser (FEL) in the Vacuum Ultraviolet regime at 109
nm wavelength (11 eV). The observed free-electron laser gain (approx. 3000) and
the radiation characteristics, such as dependency on bunch charge, angular
distribution, spectral width and intensity fluctuations all corroborate the
existing models for SASE FELs.Comment: 6 pages including 6 figures; e-mail: [email protected]
Calibration of centre-of-mass energies at LEP1 for precise measurements of Z properties
The determination of the centre-of-mass energies from the LEP1 data for 1993, 1994 and 1995 is presented. Accurate knowledge of these energies is crucial in the measurement of the Z resonance param eters. The improved understanding of the LEP energy behaviour accumulated during the 1995 energy scan is detailed, while the 1993 and 1994 measurements are revised. For 1993 these supersede the pr eviously published values. Additional instrumentation has allowed the detection of an unexpectedly large energy rise during physics fills. This new effect is accommodated in the modelling of the beam-energy in 1995 and propagated to the 1993 and 1994 energies. New results are reported on the magnet temperature behaviour which constitutes one of the major corrections to the average LEP ene rgy. The 1995 energy scan took place in conditions very different from the previous years. In particular the interaction-point specific corrections to the centre-of-mass energy in 1995 are more complicated than previously: these arise from the modified radiofrequency-system configuration and from opposite-sign vertical dispersion induced by the bunch-train mode of LEP operation. Finall y an improved evaluation of the LEP centre-of-mass energy spread is presented. This significantly improves the precision on the Z width
Linking QKD testbeds across Europe
Quantum-key-distribution (QKD) networks are gaining importance and it has
become necessary to analyze the most appropriate methods for their
long-distance interconnection. In this paper, four different methods of
interconnecting remote QKD networks are proposed. The methods are used to link
three different QKD testbeds in Europe, located in Berlin, Madrid, and Poznan.
Although long-distance QKD links are only emulated, the used methods can serve
as a blueprint for a secure interconnection of distant QKD networks in the
future. Specifically, the presented approaches combine, in a transparent way,
different fiber and satellite physical media, as well as common standards of
key-delivery interfaces. The testbed interconnections are designed to increase
the security by utilizing multipath techniques and multiple hybridizations of
QKD and post quantum cryptography (PQC) algorithms
An evaluation of factors predicting long-term response to thalidomide in 234 patients with relapsed or resistant multiple myeloma
Genetic interactions between a phospholipase A2 and the Rim101 pathway components in S. cerevisiae reveal a role for this pathway in response to changes in membrane composition and shape
Modulating composition and shape of biological membranes is an emerging mode of regulation of cellular processes. We investigated the global effects that such perturbations have on a model eukaryotic cell. Phospholipases A2 (PLA2s), enzymes that cleave one fatty acid molecule from membrane phospholipids, exert their biological activities through affecting both membrane composition and shape. We have conducted a genome-wide analysis of cellular effects of a PLA2 in the yeast Saccharomyces cerevisiae as a model system. We demonstrate functional genetic and biochemical interactions between PLA2 activity and the Rim101 signaling pathway in S. cerevisiae. Our results suggest that the composition and/or the shape of the endosomal membrane affect the Rim101 pathway. We describe a genetically and functionally related network, consisting of components of the Rim101 pathway and the prefoldin, retromer and SWR1 complexes, and predict its functional relation to PLA2 activity in a model eukaryotic cell. This study provides a list of the players involved in the global response to changes in membrane composition and shape in a model eukaryotic cell, and further studies are needed to understand the precise molecular mechanisms connecting them
Study of the photon remnant in resolved photoproduction at HERA
Photoproduction at HERA is studied in ep collisions, with the ZEUS detector, for yp centre-of-mass energies ranging from 130-270 GeV. A sample of events with two high-p(T) jets (p(T) > 6 GeV, eta < 1.6) and a third cluster in the approximate direction of the electron beam is isolated using a clustering algorithm. These events are mostly due to resolved photoproduction. The third duster is identified as the photon remnant, Its properties, such as the transverse and longitudinal energy flows around the axis of the cluster, are consistent with those commonly attributed to jets, and in particular with those found for the two jets in these events. The mean value of the photon remnant p(T) with respect to the beam axis is measured to be 2.1 +/- 0.2 GeV, which demonstrates substantial mean transverse momenta for the photon remnant
Thalidomide selectively modulates the density of cellsurface molecules involved in the adhesion cascade
Thalidomide selectively modulates the density of cellsurface molecules involved in the adhesion cascade
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