The ectoparasitic mite Tropilaelaps mercedesae (Acari, Laelapidae) as a vector of honeybee viruses

Abstract.: The ectoparasitic mites Varroa destructor and Tropilaelaps mercedesae share life history traits and both infect honeybee colonies, Apis mellifera. Since V. destructor is a biological vector of several honeybee viruses, we here test whether T. mercedesae can also be infected and enable virus replication. In Kunming (China), workers and T. mercedesae mites were sampled from three A. mellifera colonies, where workers were exhibiting clinical symptoms of deformed wing virus (DWV). We analysed a pooled bee sample (15 workers) and 29 mites for the presence of Deformed wing virus (DWV), Black queen cell virus (BQCV), Sacbrood virus (SBV), Kashmir bee virus (KBV), Acute bee paralysis virus (ABPV), and Chronic bee paralysis virus (CBPV). Virus positive samples were analysed with a qPCR. Only DWV +RNA was found but with a high titre of up to 108 equivalent virus copies per mite and 106 per bee. Moreover, in all DWV positive mites (N= 12) and in the bee sample virus-RNA was also detected using RT-PCR and tagged RT-PCR, strongly suggesting virus replication. Our data show for the first time that T. mercedesae may be a biological vector of DWV, which would open a novel route of virus spread in A. mellifer

Pediatric cataracts of different etiologies contain insoluble, calcified particles

Our recent studies in mice suggest that a crucial event for the development of cataracts is the formation of calcium-containing deposits. To examine the generality of pathologic mineralization as a novel mechanism of cataract formation, we analyzed lens material from different human cataract surgeries. Human lens material was obtained from routine cataract surgeries performed on three patients with dense, white cataracts: a 10-month-old with congenital cataracts, a 9-year-old with a uveitic cataract, and a 17-year-old with a traumatic cataract. The aspirated material from the cataract surgeries contained insoluble material that could be isolated by centrifugation. Many particles within the insoluble fraction stained with Alizarin red, a dye that stains insoluble calcified material. The appearance of these human insoluble, Alizarin red-stained particles was similar to some of those detected in homogenates from cataractous mouse lenses. These results support the hypothesis that pathologic mineralization may have a mechanistic role in the formation of cataracts of different etiologies

Disability Costs and Equivalence Scales in the Older Population in Great Britain

We use a standard of living (SoL) approach to estimate older people's disability costs, using data on 8000 individuals from the U.K. Family Resources Survey. We extend previous research in two ways. First, by allowing for a more flexible relationship between SoL and income, the structure of the estimated disability cost and equivalence scale is not dictated by a restrictive functional form assumption. Second, we allow for the latent nature of disability and SoL, addressing measurement error in the disability and SoL indicators in surveys. We find that disability costs are strongly related to severity of disability, and vary with income in absolute and proportionate terms. Older people above the median disability level require an extra �99 per week (2007 prices) on average to reach the SoL of an otherwise similar person at the median. Costs faced by older people in the highest decile of disability average �180

New mobilities across the lifecourse: A framework for analysing demographically-linked drivers of migration

Date of acceptance: 17/02/2015Taking the life course as the central concern, the authors set out a conceptual framework and define some key research questions for a programme of research that explores how the linked lives of mobile people are situated in time–space within the economic, social, and cultural structures of contemporary society. Drawing on methodologically innovative techniques, these perspectives can offer new insights into the changing nature and meanings of migration across the life course.Publisher PDFPeer reviewe

High flux cold Rubidium atomic beam for strongly coupled Cavity QED

This paper presents a setup capable of producing a high-flux continuous beam of cold rubidium atoms for cavity QED experiments in the regime of strong coupling. A 2 $D^+$ MOT, loaded by rubidium getters in a dry film coated vapor cell, fed a secondary moving-molasses MOT (MM-MOT) at a rate of 1.5 x $10^{10}$ atoms/sec. The MM-MOT provided a continuous beam with tunable velocity. This beam was then directed through the waist of a 280 $\mu$m cavity resulting in a Rabi splitting of more than +/- 10 MHz. The presence of sufficient number of atoms in the cavity mode also enabled splitting in the polarization perpendicular to the input. The cavity was in the strong coupling regime, with parameters (g, $\kappa$, $\gamma$)/2$\pi$ equal to (7, 3, 6)/ 2$\pi$ MHz.Comment: Journal pape

Well-Being in Adolescence-An Association With Health-Related Behaviors: Findings From Understanding Society, the UK Household Longitudinal Study

The objective of this study was to investigate the demographic distribution of selected health-related behaviors and their relationship with different indicators of well-being. The data come from Wave 1 of the youth panel of Understanding Society household panel study. The Strengths and Difficulties Questionnaire (SDQ) measured socio-emotional difficulties. Markers of happiness in different life domains were combined to assess levels of happiness. Generally, younger youth participated in more health-protective behaviors, while older youth reported more health-risk behaviors. Higher consumption of fruit and vegetables and greater participation in sport were associated with higher odds of high happiness. Healthier eating was associated with lower odds of socio-emotional difficulties, while increased fast food consumption was associated with higher odds of socio-emotional difficulties. Smoking, drinking, and decreased sport participation were all associated with socio-emotional difficulties. Health-protective behaviors were associated with happiness, while health-risk behaviors were associated with socio-emotional difficulties. © The Author(s) 2013

Identity work and the `unemployed' worker: age, disability and the lived experience of the older unemployed

This article seeks to explore how older individuals negotiate and manage their self-identity in relation to work while situated without paid employment. After reviewing the current positions of the older unemployed in the UK, noting the substantial overlap between age and disability, we turn our attention to conceptualizing the lived experiences of individuals through exploring `identity work' as a means of understanding a non-working work identity. Based upon focus group interviews, our empirical analysis focuses on key dimensions of participants' identity practice and how they sought to manage the following social processes: imposed identities; crafting working identities; and contesting unfavourable working identities.The conclusion contextualizes the findings against a backdrop of increasing individualistic discourses underpinning approaches to employability, closes with the policy implications arising from this study, and makes suggestions for future research agendas. </jats:p

A Longitudinal Analysis of Moving Desires, Expectations and Actual Moving Behaviour

Residential mobility theory proposes that moves are often preceded by the expression of moving desires and expectations. Much research has investigated how individuals form these premove thoughts, with a largely separate literature examining actual mobility. Although a growing number of studies link premove thoughts to subsequent moving behaviour, these often do not distinguish explicitly between different types and combinations of premove thoughts. Using 1998–2006 British Household Panel Survey data, this study investigates whether moving desires and expectations are empirically distinct premove thoughts. Using multinomial regression models we demonstrate that moving desires and expectations have different meanings, and are often held in combination: the factors associated with expecting to move differ depending upon whether the move is also desired (and vice versa). Next, using panel logistic regression models, we show that different desire–expectation combinations have different effects on the probability of subsequent moving behaviour. The study identified two important groups generally overlooked in the literature: those who expect undesired moves and those who desire to move without expecting this to happen.The definitive, peer reviewed and edited version of this article is published in Environment and Planning A, 2011, 43(11), pp. 2742-2760, doi:10.1068/a44105