25 research outputs found
The Significance of Education for Establishment in the Care Sector: Women and Men and Care Workers with a Migrant Background
Saccharomyces cerevisiae pneumonia in a patient with acquired immune deficiency syndrome
Dynamic ultrasound imaging : a multivariate approach for the analysis and comparison of time-dependent musculoskeletal movements
BACKGROUND: Muscle functions are generally assumed to affect a wide variety of conditions and activities, including pain, ischemic and neurological disorders, exercise and injury. It is therefore very desirable to obtain more information on musculoskeletal contributions to and activity during clinical processes such as the treatment of muscle injuries, post-surgery evaluations, and the monitoring of progressive degeneration in neuromuscular disorders.The spatial image resolution achievable with ultrasound systems has improved tremendously in the last few years and it is nowadays possible to study skeletal muscles in real-time during activity. However, ultrasound imaging has an inherent problem that makes it difficult to compare different measurement series or image sequences from two or more subjects. Due to physiological differences between different subjects, the ultrasound sequences will be visually different -- partly because of variation in probe placement and partly because of the difficulty of perfectly reproducing any given movement. METHODS: Ultrasound images of the biceps and calf of a single subject were transformed to achieve congruence and then efficiently compressed and stacked to facilitate analysis using a multivariate method known as O2PLS. O2PLS identifies related and unrelated variation in and between two sets of data such that different phases of the studied movements can be analysed. The methodology was used to study the dynamics of the Achilles tendon and the calf and also the Biceps brachii and upper arm. The movements of these parts of the body are both of interest in clinical orthopaedic research. RESULTS: This study extends the novel method of multivariate analysis of congruent images (MACI) to facilitate comparisons between two series of ultrasound images. This increases its potential range of medical applications and its utility for detecting, visualising and quantifying the dynamics and functions of skeletal muscle. CONCLUSIONS: The most important results of this study are that MACI with O2PLS is able to consistently extract meaningful variability from pairs of ultrasound sequences. The MACI method with O2PLS is a powerful tool with great potential for visualising and comparing dynamics between movements. It has many potential clinical applications in the study of muscle injuries, post-surgery evaluations and evaluations of rehabilitation, and the assessment of athletic training interventions
An analysis of Eurasian badger (Meles meles) population dynamics: implications for regulatory mechanisms
Based on 15 years of observations of a badger (Meles meles) population at Wytham Woods in the central United Kingdom, we investigated which parameters governed demographic changes, using data recording the life histories of 868 individuals. We modeled the population in terms of a stage-classified matrix, giving an exponential population growth rate of r = 0.063 (λ = 1.065). Population elasticity values, derived from this matrix, produced a relative order of importance of regulatory parameters governing this population growth rate, of: adult survival (Pa) > fertility (F) > juvenile survival (Pj) > age at 1st reproduction (α) > age at last reproduction (ω). Thus, changes in Pa and F have the greatest potential to influence population growth rate. The population underwent a dramatic change in the last 5 years of the study, with a decline, then stabilization in population growth. However, this change was not related to any change in elasticity patterns between the 2 periods. Comparing the latter period to the preceding period of marked population growth revealed that fertility rate had little actual influence, whereas adult and juvenile survival rates were far more influential demographic variables. These findings prompted a 2nd, retrospective, analytical approach, a life-table response experiment (LTRE), revealing that the importance of Pj in the LTRE contrasted with its lesser prospective importance in the elasticity analysis. Change in fertility (ΔF) apparently had little environmental or genetic scope (according to the results of either technique) to influence regulation in this population. We also tested for delayed density dependence using the theta logistic model. Because territorial animals are expected to respond quickly to the effects of density dependence, corresponding to theta < 1, our rejection of this hypothesis indicated that the restrictions of territorial sociospatial regulation are relaxed in this badger population. These results are used to highlight population vulnerabilities