The Grammar of Honour and Revenge

There is a rich anthropological literature on honour and revenge, but more often than not, analyses are limited to cultural or historical expressions of the phenomena. As a corollary, the recent re-emergence of honour in Europe is usually explained in terms of non-western immigrants who bring notions of honour as part of their cultural luggage. However, the practice of honour and revenge by Danish Motorcycle Clubs suggests that such an approach is insufficient. The ambition in the article is to go beyond the various cultural expressions and search for a basic ‘grammar’ that can explain why honour becomes a valid theme in some societies and in certain situations. In that endeavour, two questions are vital: What is honour all about? And what is the logic in the perception that lost honour can be restored through revenge? Analysis of a prototypical feuding community in Northern Pakistan concludes that honour is best understood as a family’s publicly recognized capability for self-defence, and that revenge is a means to restore that image if it has been shattered. I contend that honour – in the sense of self-defence – is vital in societies where there is no accessible level of appeal in cases of conflict. Furthermore, the logic of honour that prevails among competing families in Northern Pakistan can also occasionally be recognized at the state level in international politics since there is no reliable supranational level of appeal in cases of perceived injustice

Zoom in on antibody aggregates:A potential pitfall in the search of rare EV populations

High-resolution flow cytometers (hFCM) are used for the detection of extracellular vesicles (EV) in various biological fluids. Due to the increased sensitivity of hFCM, new artifacts with the potential of interfering with data interpretation are introduced, such as detection of antibody aggregates. The aim of this study was to investigate the extent of aggregates in labels commonly used for the characterization of EVs by hFCM. Furthermore, we aimed to compare the efficacy of centrifugation and filtering treatments to remove aggregates, as well as to quantify the effect of the treatments in reducing aggregates. For this purpose, we labeled phosphate buffered saline (PBS) with fluorescently conjugated protein labels and antibodies after submitting them to 5, 10, or 30 min centrifugation, filtering or washed filtering. We investigated samples by hFCM and quantified the amount of aggregates found in PBS labeled with untreated and pre-treated labels. We found a varying amount of aggregates in all labels investigated, and further that filtering is most efficient in removing all but the smallest aggregates. Filtering protein labels can reduce the extent of aggregates; however, how much remains depends on the specific labels and their combination. Therefore, it is still necessary to include appropriate controls in a hFCM study of EVs

Bowen-Ratio Comparisons with Lysimeter Evapotranspiration

Water use in agriculture by different cropping systems is of interest in determining crop water use efficiency of different tillage practices that will lead to reduced crop production risk. Lysimeters are considered the standard for evapotranspiration (ET) measurements; however, these units are often not replicated and are few in number at any given location. Our objective was to determine if a simple Bowen-ratio system with nonexchanging psychrometers could provide accurate measurements of ET from lentil (Lens culinaris Medikus) in a semiarid climate. The study was conducted in 1993 and 1994 on two adjacent 180- by 180-m fields with weighing lysimeters (1.68 by 1.68 by 1.83 m) located in the center of each field, on a Williams loam (fine-loamy, mixed Typic Argiboroll) soil near Sidney, MT. A Bowen-ratio system comprised of two nonexchanging psychrometers and anemometers at 0.25 and 1.25 m above the plant canopy surface was placed in the lentil field along with a net radiometer and soil heat flux plate. Precipitation during the growing season from planting to swathing was 367 mm in 1993 and 227 mm in 1994. In 1993, soil water content of the lysimeter was greater than the field after large precipitation events around Day of Year (DOY) 210, even though the lysimeter was drained. After this time, the lysimeter ET exceeded that measured by the Bowen-ratio system. Agreement was closer in 1994, when precipitation was near normal and there was no excess soil water in the lysimeter. Cumulative ET totals from the lysimeter were reflective of the seasonal precipitation patterns. Differences between the lysimeter and Bowen-ratio occurred when there was excess precipitation and inadequate drainage from the lysimeter. Half-hourly ET fluxes from lysimeter and Bowen-ratio values agreed to within 10% throughout the season. Bowen-ratio systems with nonexchanging psychrometers can provide satisfactory estimates of daily and seasonal ET and can be used to estimate ET in semiarid climates

Lentil water use and fallow water loss in a semiarid climate

With renewed interest in legumes for green manures or as partial summer fallow replacement crops, it is important to know water requirements of these crops in semiarid agriculture. Our objective was to evaluate seasonal water use by black lentil (Lens culinaris Medikus cv. Indianhead), a potential fallow replacement crop, and to relate water use to parameters useful as soil water management tools. We measured evapotranspiration (ET) from two precision weighing lysimeters located on a Williams loam (fine-loamy, mixed Typic Argiboroll) near Sidney, MT. The lysimeters were in adjacent 180- by 180-m fields in a typical strip-crop environment of the semiarid northern Great Plains. Bowen ratio estimates of ET were also obtained. Lentil was seeded no-till into wheat (Triticum aestivum L.) stubble on one lysimeter field in 1993, and the other was left in chemical fallow. Seeded and fallow fields were rotated in 1994. Water loss by ET from lentil and fallow lysimeters was the same ( 25 mm) for 3 wk following seeding. Plant height was related to growing degree days (GDD) in both years. Cumulative ET was related to GDD for both years until about 800 GDD, corresponding to nearly 300 mm ET. Deciding how much water to sacrifice (with hopes of recovery during the noncrop period) becomes a matter of judgment about probable rainfall. At full bloom ( 2 Mg ha' dry matter production), the lentil crop used about 50 to 70 mm more water than fallow. Probably no more than 50 mm of water loss above that from fallow should be sacrificed if a grain crop is to be seeded the following year. From a practical standpoint, because plant height was closely related to both GDD and cumulative ET, it is plausible that a simple measure of lentil height (about 350 mm maximum) can give sufficient accuracy for determining when lentil growth, as a partial summer fallow replacement crop in a semiarid climate, should be terminated

Diabetes is a Risk Factor for Pulmonary Tuberculosis: A Case-Control Study from Mwanza, Tanzania.

Diabetes and TB are associated, and diabetes is increasingly common in low-income countries where tuberculosis (TB) is highly endemic. However, the role of diabetes for TB has not been assessed in populations where HIV is prevalent. A case-control study was conducted in an urban population in Tanzania among culture-confirmed pulmonary TB patients and non-TB neighbourhood controls. Participants were tested for diabetes according to WHO guidelines and serum concentrations of acute phase reactants were measured. The association between diabetes and TB, and the role of HIV as an effect modifier, were examined using logistic regression. Since blood glucose levels increase during the acute phase response, we adjusted for elevated serum acute phase reactants. Among 803 cases and 350 controls the mean (SD) age was 34.8 (11.9) and 33.8 (12.0) years, and the prevalence of diabetes was 16.7% (95% CI: 14.2; 19.4) and 9.4% (6.6; 13.0), respectively. Diabetes was associated with TB (OR 2.2, 95% CI: 1.5; 3.4, p<0.001). However, the association depended on HIV status (interaction, p = 0.01) due to a stronger association among HIV uninfected (OR 4.2, 95% CI: 1.5; 11.6, p = 0.01) compared to HIV infected (OR 0.1, 95% CI: 0.01; 1.8, p = 0.13) after adjusting for age, sex, demographic factors and elevated serum acute phase reactants. Diabetes is a risk factor for TB in HIV uninfected, whereas the association in HIV infected patients needs further study. The increasing diabetes prevalence may be a threat to TB control

Gastric cancer and Helicobacter pylori: a combined analysis of 12 case control studies nested within prospective cohorts

BACKGROUND: The magnitude of the association between Helicobacter pylori and incidence of gastric cancer is unclear. H pylori infection and the circulating antibody response can be lost with development of cancer; thus retrospective studies are subject to bias resulting from classifi- cation of cases as H pylori negative when they were infected in the past. AIMS: To combine data from all case control studies nested within prospective cohorts to assess more reliably the relative risk of gastric cancer associated with H pylori infection.To investigate variation in relative risk by age, sex, cancer type and subsite, and interval between blood sampling and cancer diagnosis. METHODS: Studies were eligible if blood samples for H pylori serology were collected before diagnosis of gastric cancer in cases. Identified published studies and two unpublished studies were included. Individual subject data were obtained for each. Matched odds ratios (ORs) and 95% confidence intervals (95% CI) were calculated for the association between H pylori and gastric cancer. RESULTS: Twelve studies with 1228 gastric cancer cases were considered. The association with H pylori was restricted to noncardia cancers (OR 3.0; 95% CI 2.3–3.8) and was stronger when blood samples for H pylori serology were collected 10+ years before cancer diagnosis (5.9; 3.4–10.3). H pylori infection was not associated with an altered overall risk of cardia cancer (1.0; 0.7–1.4). CONCLUSIONS: These results suggest that 5.9 is the best estimate of the relative risk of non-cardia cancer associated with H pylori infection and that H pylori does not increase the risk of cardia cancer. They also support the idea that when H pylori status is assessed close to cancer diagnosis, the magnitude of the non-cardia association may be underestimated

Effects of sample handling and analytical procedures on thyroid hormone concentrations in pregnant women's plasma

Background: Maternal thyroid function is a critical mediator of fetal brain development. Pregnancy-related physiologic changes and handling conditions of blood samples may influence thyroid hormone biomarkers. We investigated the reliability of thyroid hormone biomarkers in plasma of pregnant women under various handling conditions. Methods: We enrolled 17 pregnant women; collected serum and plasma were immediately frozen. Additional plasma aliquots were subjected to different handling conditions before the analysis of thyroid biomarkers: storage at room temperature for 24 or 48 hours before freezing and an extra freeze-Thaw cycle. We estimated free thyroid hormone indices in plasma based on T3 uptake. Results: High correlations between plasma and serum (>0.94) and intraclass correlation coefficients for plasma handling conditions (0.96 to 1.00) indicated excellent reliability for all thyroid hormone biomarkers. Conclusion: Delayed freezing and freeze-Thaw cycles did not affect reliability of biomarkers of thyroid function in plasma during pregnancy. See video abstract at, http://links.lww.com/EDE/B180