Cancer registry in Iran: A brief overview

Cancer registry is an important tool for any successful cancer control program. The first formal cancer related data from Iran were published in 1956. In 1969, observations documenting a high incidence of esophageal cancer in the Caspian Littoral, urged researchers to set up the first population-based cancer registry in this region. This cancer registry was established jointly by University of Tehran and the International Agency for Research on Cancer (IARC). In 1976, another cancer registry started its activities in Fars Province. In 1984, the Parliament passed a bill mandating the report of all tissues "diagnosed or suspected as cancer tissue" to the Ministry of Health. While only 18% of all estimated cancer cases were reported in first reports, this rate increased to 81% in 2005 In 1998, Tehran Population-Based Cancer Registry started to collect data from cases of cancer referred to the treatment and diagnostic facilities throughout the Tehran metropolis. Digestive Disease Research Center, Tehran University of Medical Sciences, established four new population-based cancer registries in Northern Iran and another in Kerman Province in the south. These five provinces have a total population of about 9.5 million, and constitute about 16% of the total population of Iran. While the pathology-based cancer registration is in place, we hope that the addition of the population-based cancer registries, and establishment of new registries in poorly-covered areas, will improve cancer reporting in the country

Antibacterial effects of sodium acetate on vacuum packaged rainbow trout (Oncorhynchus mykiss) in chilled storage

We investigated antibacterial effects of sodium acetate (2%) on microbial, biochemical and sensory characteristics of rainbow trout (Oncorhynchus mykiss) vacuum packed and stored during 18 days at 2±1°C. Initial total bacteria count was 2.82 logfulg, indicating quality of the prepared fish was high. Psycrotrophic bacteria of unheated and treated vacuum packed samples reached maximum acceptable limit (7 logdaig) after 14 and 18 days of storage, respectively. Entrobacteriaceae and lactic acid bacteria count were lower than maximum acceptable limit during 18 days. Therefore, we based determination of microbial assessment of products shelf life on time to reach maximal acceptable limit for Psycrotrophic bacteria in treatments. There were no significant difference (P>0.05) between vacuum packed and sodium acetate vacuum packed samples in TBA and TMA values. During most of examination time, TBA and TMA values of sodium acetate vacuum packed samples were lower than untreated vacuum packed samples. According to microbial and sensory analyses, shelf life of vacuum packed and sodium acetate vacuum packed samples was 15 and 18 days, respectively. This is an indication of positive antibacterial effects of sodium acetate on shelf life extension of rainbow trout products

The relationship between nurses' clinical competency and job stress in Ahvaz university hospital, 2013

زمینه و هدف: صلاحیت بالینی پرستاری، شایستگی کاربرد همزمان دانش، مهارت، نگرش ها و ارزش ها در مراقبت از بیمار است که به دلیل اهمیت آن اخیراً مورد توجه بیشتری قرار گرفته است. با توجه به اهمیت روز افزون موضوع صلاحیت پرستاری، شناخت عوامل مرتبط با آن و از جمله استرس شغلی ضروری به نظر می رسد؛ لذا مطالعه حاضر با هدف تعیین رابطه صلاحیت بالینی و استرس شغلی پرستاران شاغل در بیمارستان های دانشگاهی شهر اهواز در سال1392 انجام شد. روش بررسی: در این پژوهش توصیفی- تحلیلی که به صورت مقطعی در طی سال 1392 انجام شد، 80 نفر پرستار شاغل در بیمارستان های آموزشی شهر اهواز از طریق نمونه گیری تصادفی انتخاب و وارد مظالعه شدند. ابزار گردآوری داده ها شامل پرسشنامه های استرس شغلی Osipow و پرسشنامه صلاحیت بالینی Benner بود که به صورت خود ایفاء تکمیل گردیدند. میزان صلاحیت بالینی پرستاران ارزیابی و ارتباط آن با استرس شغلی تعیین شد. یافته ها: بیشتر پرستاران (3/81 درصد) دارای استرس شغلی متوسط بودند. میانگین نمره کل صلاحیت بالینی پرستاران 48/18± 15/61 بود. آزمون همبستگی پیرسون نشان داد که بین استرس شغلی و صلاحیت بالینی پرستاران در تمام حیطه های آن همبستگی منفی و معنی داری وجود دارد (01/0>P). همچنین بین میزان استرس شغلی و بکارگیری صلاحیت بالینی کل ارتباط معنی داری وجود داشت (001/0>P). نتیجه گیری: بر اساس نتایج مطالعه حاضر، افزایش استرس شغلی پرستاران با کاهش صلاحیت های بالینی آنها رابطه دارد که بایستی مورد توجه مدیران پرستاری قرار گیرد

Types and Causalities in Dead Patients Due to Traumatic Injuries

Background: Trauma constitutes a major public health problem in our country and contributes significantly to unacceptably high morbidity and mortality. Objectives: This study aimed to evaluate the epidemiology of trauma in dead patients referred to Shahid Rajaee Trauma Hospital, Shiraz, Iran. Patients and Methods: In a cross-sectional study, all patients with trauma admitted to our center were enrolled between March 2011 and February 2012. Age, gender, months of referring, causalities, and injured body parts of the victims were extracted from the data registry and analyzed. Results: A total of 9113 patients, including 7163 (78.6%) males and 1950 (21.4%) females were evaluated. Among them, 479 patients (5.3%) had died. There was a significant difference between the age of alive and dead patients (35.70 ± 0.18 and 45.44 ± 1.01 years, respectively (P < 0.001)). In addition, dead men had significantly higher percentage than alive men (83.7% and 78.3%, respectively, P = 0.005). The highest percentages of men and women who referred to our center and died were in September. Crashing by car had the most frequency of dead (247 cases) in referred patients and motorcycle accident, stabbing, and falling related injuries with 67, 36 and 26 dead cases were in the next ranks. Thorax injury had the most frequency between dead patients (53.2% of all dead) and the intracranial injury and trauma to extremities altogether were in the next ranks, which constituted more than 18.8% of all dead. Conclusions: Our data demonstrated that car and motorcycle accidents are the most important cause of trauma and thorax trauma had the most frequency among dead patients. Epidemiological evaluations and preventive measures such as this study should be conducted to provide valuable data

The effect of intra-articular meperidine and bupivacaine 0.5 on postoperative pain of arthroscopic knee surgery; a randomized double blind clinical trial

Background: Arthroscopic knee surgeries have a painful postoperative course, which often necessitates acute pain management. Among different analgesia techniques, Intra-articular injection is the technique of choice for many pain specialists, based on its confined effect to the surgical site (knee), lack of systemic effects and promotion of safe early ambulation. Objectives: The aim of this study was to compare analgesic effects of intra-articular meperidine, bupivacaine 0.5 or their combination after knee arthroscopic surgery. Patients and Methods: Sixty ASA class I-II patients� candidates for arthroscopy knee surgery enrolled in a randomized double blind study to receive either 20 mL of bupivacaine 0.5; 100 mg meperidine (diluted in normal saline) or bupivacaine 0.5 along with 100 mg meperidine. A written informed consent was obtained from all patients. Postoperative analgesia duration, VAS at 2, 6, 12 and 24 hours, the Results: The bupivacaine-meperidine group had better duration of postoperative analgesia (P = 0.001), latter first analgesic request (P � first analgesic request time, total fentanyl consumption in first 24 hours, patients� satisfaction and adverse effects were recorded. 0.001), lower total fentanyl consumption in first 24 hours after the operation (P = 0.001), less mean VAS at 2 hours (P = 0.001) and more patients� overall satisfaction (P = 0.01) compared with each medication alone. VAS at 6, 12 and 24 postoperative hours were not different between the groups of study. No adverse effects were observed. Conclusions: Although postoperative intra-articular meperidine is a better alternative for bupivacaine, their combination could improve their analgesic effects compared with each other alone. © 2015, Iranian Society of Regional Anesthesia and Pain Medicine (ISRAPM)

Endoscopic screening for precancerous lesions of the esophagus in a high risk area in northern Iran

Background: Esophageal squamous cell carcinoma (ESCC) is a major health problem in many developing countries, including Iran. ESCC has a very poor prognosis, largely due to late diagnosis. As a first step in developing an early detection and treatment program, we conducted a population-based endoscopic screening for ESCC and its precursor lesion, esophageal squamous dysplasia (ESD), in asymptomatic adults from Golestan Province, northern Iran (a high-risk area for ESCC) to evaluate the feasibility of such a program and to document the prevalence and risk factor correlates of ESD. Methods: This cross-sectional study was conducted among participants of the Golestan Cohort Study (GCS), a population-based cohort of 50,000 adults in eastern Golestan Province. Randomly selected GCS participants were invited by telephone. Those who accepted were referred to a central endoscopy clinic. Eligible subjects who consented were asked to complete a brief questionnaire. Detailed information about selected risk factors was obtained from the GCS main database. Endoscopic examination with was performed with Lugol's iodine staining; biopsies were taken from unstained lesions as well as the normally stained mucosa of the esophagus, and the biopsies were diagnosed by expert pathologists according to previously described criteria. Results: In total, 1906 GCS subjects were invited, of whom only 302 (15.8%) were successfully enrolled. Esophagitis (29.5%) and ESD (6.0%) were the most common pathological diagnoses. Turkmen ethnicity (adjusted OR = 8.61; 95%CI: 2.48-29.83), being older than the median age (OR = 7.7; 95% CI: 1.99-29.87), and using deep frying cooking methods (OR = 4.65; 95%CI: 1.19-18.22) were the strongest predictors for ESD. There were significant relationships between esophagitis and smoking (p-value<0.001), drinking hot tea (P value = 0.02) and lack of education (P value = 0.004). Conclusion: We observed a low rate of participation in endoscopic screening. The overall prevalence of ESD was 6.0%. Developing non-endoscopic primary screening methods and screening individuals with one or more risk factors may improve these rates

THE CRYSTAL AND MOLECULAR STRUCTURE OF N, N&apos;-3, 6-DIOXA-1, 8-OCTANEBIS (SALICYLALDIMINE), C 20 H 24 N 2 O 24

Abstract - The crystal structure of the compound C 20 H 24 N 2 O 24 was determined by direct methods. The crystals are monoclinic, space group P2 1 /n, and unit cell parameters are: a= 10.234

U-Pb zircon geochronology, geochemistry, and petrogenesis of the Hamech intrusions in the Kuh-e-Shah volcano-plutonic complex, Eastern Iran

The Hamech area is located in the west of Kuh-e-Shah volcano-plutonic complex, close to the boundary between the Lut Block and Sistan Suture Zone (SSZ), and is composed of monzonite to diorite porphyries and rare gabbro that intruded into older volcanic rocks. U-Pb zircon dating indicates an age of 36.9 ± 1 Ma for gabbro (Late Eocene, Priabonian) and 38.6 ± 0.5 Ma for dacite (Late Eocene, Bartonian). Geochemically, the studied intrusions are dominantly I-type, high-K calc-alkaline, and metaluminous features. Primitive mantle-normalized trace-element spider diagrams of these rocks present enrichment in ion lithophile elements such as Cs, Rb, Ba, K, and Sr and depletion in high field strength elements such as Nb, Ti, Zr, and heavy rare earth elements. Besides, chondrite-normalized rare earth elements plots of the rocks show enrichment in light rare earth elements (6.85 < LaN/YbN < 9.72) and a lack or weak negative Eu anomaly (Eu/Eu* = 0.81–1.02). The initial 87Sr/86Sr and 143Nd/144Nd ratios for the rocks from 0.704541 to 0.704880 and from 0.512633 to 0.512691, respectively, when recalculated to an age of 39 Ma. The εNd(i) values vary from +0.87 to +1.99, which fits into a suprasubduction mantle wedge source for the parental melts. All data suggest that the Hamech intrusions developed in a low maturity continental margin arc setting related to the convergence of the Afghan and Lut Blocks and subduction of Sistan oceanic crust during the Eocene.publishe