Rehabilitation Of A Patient Having Few Natural Teeth With Maxillary Overdenture –A Clinical Report

The over denture, a complete or partial denture prosthesis constructed over existing teeth or root structure is not a new concept in a technical approach to a prosthodontic problem. Today with the stress on preventive measures in prosthodontics, the use of over dentures has increased to the point where it is feasible alternative to most treatment plan outlines in the construction of a prosthesis for patients with remaining teeth. Here a 54 years male patient  is rehabilitated with fabrication of maxillary over denture with copings and mandibular removable complete denture. Key words: Over denture, Cast metal copings, Maxillary arc

Leiomyosarcoma of Colon Presented as Retroperitoneal Mass: A Rare Case Report

Introduction: Retroperitoneal tumors are lesions with diverse pathological subtypes that originate from the retroperitoneal space. About forty percent of these tumors are benign. These lesions are often surrounded and associated with vital abdominal blood vessels; therefore, a complete surgical resection is difficult.Presentation of the case: Here we are presenting a 42-year-old female presented with abdominal lump from last two monthswith persistent abdominal pain from one month. The computed tomography and ultrasound scan confirmed the presence of a solid retroperitoneal tumor. She underwent surgical exploration and histology confirmed that the tumor composed of spindle shaped cells disposed in intersecting fascicles, whirling and storiform pattern. The tumor cells are oval to spindle shaped with blunt ended nuclei, dispersed chromatin and moderate amount of cytoplasm. On immunohistochemical staining, tumor cells were positive for vimentin. The patient was followed up for two years, with no evidence of tumor recurrence. No standardized guidelines have been established for its treatment because too small a number of cases have been reported, but surgical resection was considered the treatment of choice. In summary, we report a unique case who developed leiomyosarcoma of colon presented as retroperitoneal mass.Conclusion: In this case report we described this rare occurrence of leiomyosarcoma of colon and highlight the diagnostic difficulties such cases can pose along with a review of relevant literature

Assessment of the Effects Following Subchronic Dosing with Sodium Tungstate on Male Reproductive System in Wistar Rats

Sodium tungstate is one of the inorganic compound with insulinomimmetic properties. The present study was conducted to investigate the effects of sodium tungstate on male reproductive system. The experimental rats were randomly divided into two groups (n=8/ group). The first group was used as a control, the second group was used to study the effect of sodium tungstate. Sodium tungstate was orally administrated to male Wistar rats at a dose level of 50mg/kg.bd wt. /day for 60 days. The daily administration produced no significant changes in the body weight gain. No significant changes were observed in the weight of testis, epididymis, seminal vesicles, ventral prostate, liver, kidney, and adrenal gland. Exogenous  supplementation with Sodium tungstate produce non significant depletion in protein, glycogen and sialic acid content in testis and epididymis and fructose level in seminal vesicle. Cholesterol level showed  no significant change in testis and epididymis. However, Spermatozoon motility and epididymal sperm concentration showed no significant changes. Plasma testosterone, FSH and LH level showed non significant decline in the sodium tungstate treated animals when compared to the control animals.The histology of testis and cauda epididymis showed no severe histological alterations when compared to control group. The results conclude that sodium tungstate (50 mg/kg bd.wt./day) did not cause any severe histological and biochemical alteration in male reproductive system

Rare Axillary Sebaceous Cyst Carcinoma: A Case Report with review of literature

Introduction: Sebaceous Cyst carcinoma (SCC) is a rare aggressive skin cancer derived from the epithelium of sebaceous glands. Sebaceous cyst carcinoma accounts to 1% of cutaneous malignancy. Sebaceous cyst carcinomas are generally divided into those occurring in ocular (75%) or extraocular locations. SCC is very rare in axilla and confused with secondaries from breast carcinoma or lymphoma.Presentation of the case: Here we are presenting a case of 38 year old male, who presented with painless, progressive swelling on left axilla from one year. He was evaluated with ultrasound breast and axilla and a fine needle ultrasound from the swelling. The FNA of ulcerated lesion in the left axilla showed positive malignant epithelial cells. The tumour cells display oval hyperchromatic to vesicular nuclei with moderate nuclear pleomorphism, conspicuous nucleoli in places and scant cytoplasm. The tumour cells are strongly immunoreactive for CK7, EMA, and CD10, weakly and focally reactive for CK20, and non-reactive for vimentin.Conclusion: In conclusion, Sebaceous Cell Carcinoma is a rare and aggressive malignancy. The fumigating mass in the axilla may rarely be a sebaceous cyst carcinoma, may present with or without breast lump, prognosis is very poor therefore should be treated aggressively and adequately

The usefulness of a new rapid diagnostic test, the First Response® Malaria Combo (pLDH/HRP2) card test, for malaria diagnosis in the forested belt of central India

<p>Abstract</p> <p>Background</p> <p>Malaria presents a diagnostic challenge in tribal belt of central India where two Plasmodium species, <it>Plasmodium falciparum </it>and <it>Plasmodium vivax</it>, are prevalent. In these areas, rapid detection of the malaria parasites and early treatment of infection remain the most important goals of disease management. Therefore, the usefulness of a new rapid diagnostic (RDT), the First Response^®Combo Malaria Ag (pLDH/HRP2) card test was assessed for differential diagnosis between <it>P. falciparum </it>with other Plasmodium species in remote villages of Jabalpur district.</p> <p>Methods</p> <p>A finger prick blood sample was collected to prepare blood smear and for testing with the RDT after taking informed consent. The figures for sensitivity, specificity, accuracy and predictive values were calculated using microscopy as gold standard.</p> <p>Results</p> <p>Analysis revealed that overall, the RDT was 93% sensitive, 85% specific with a positive predictive value (PPV) of 79%, and a negative predictive value (NPV) of 95%. The accuracy 88% and J-index was 0.74. For <it>P. falciparum</it>, the sensitivity and specificity of the test were 96% and 95% respectively, with a PPV of 85% and a NPV of 99%. The RDT accuracy 95% and J-index was 0.84. For non-falciparum malaria, the sensitivity, specificity and accuracy were 83%, 94% and 92% respectively with a PPV of 69% and a NPV of 97%.</p> <p>Conclusion</p> <p>The RDTs are easy to use, reliable and simple to interpret. RDTs are more suited to health workers in situations where health services are deficient or absent. Therefore, the test can be used as an epidemiological tool for the rapid screening of malaria.</p

MUCOMETRA ASSOCIATED WITH CYSTIC OVARIAN DISEASE AND UTERINE UNICORNIS IN SAHIWAL COW

Present study reports successful management of a case of mucometra associated with cystic ovarian follicles and uterine unicornis in a Sahiwal cow

Rust (Uromyces viciae-fabae Pers. de-Bary) of Pea (Pisum sativum L.): Present Status and Future Resistance Breeding Opportunities

Uromyces viciae-fabae Pers. de-Bary is an important fungal pathogen causing rust in peas (Pisum sativum L.). It is reported in mild to severe forms from different parts of the world where the pea is grown. Host specificity has been indicated in this pathogen in the field but has not yet been established under controlled conditions. The uredinial states of U. viciae-fabae are infective under temperate and tropical conditions. Aeciospores are infective in the Indian subcontinent. The genetics of rust resistance was reported qualitatively. However, non-hypersensitive resistance responses and more recent studies emphasized the quantitative nature of pea rust resistance. Partial resistance/slow rusting had been described as a durable resistance in peas. Such resistance is of the pre-haustorial type and expressed as longer incubation and latent period, poor infection efficiency, a smaller number of aecial cups/pustules, and lower units of AUDPC (Area Under Disease Progress Curve). Screening techniques dealing with slow rusting should consider growth stages and environment, as both have a significant influence on the disease scores. Our knowledge about the genetics of rust resistance is increasing, and now molecular markers linked with gene/QTLs (Quantitative Trait Loci) of rust resistance have been identified in peas. The mapping efforts conducted in peas came out with some potent markers associated with rust resistance, but they must be validated under multi-location trails before use in the marker-assisted selection of rust resistance in pea breeding programs

Development and optimization of NIRS prediction models for simultaneous multi-trait assessment in diverse cowpea germplasm

Cowpea (Vigna unguiculata (L.) Walp.) is one such legume that can facilitate achieving sustainable nutrition and climate change goals. Assessing nutritional traits conventionally can be laborious and time-consuming. NIRS is a technique used to rapidly determine biochemical parameters for large germplasm. NIRS prediction models were developed to assess protein, starch, TDF, phenols, and phytic acid based on MPLS regression. Higher RSQexternal values such as 0.903, 0.997, 0.901, 0.706, and 0.955 were obtained for protein, starch, TDF, phenols, and phytic acid respectively. Models for all the traits displayed RPD values of >2.5 except phenols and low SEP indicating the excellent prediction of models. For all the traits worked, p-value ≥ 0.05 implied the accuracy and reliability score >0.8 (except phenol) ensured the applicability of the models. These prediction models will facilitate high throughput screening of large cowpea germplasm in a non-destructive way and the selection of desirable chemotypes in any genetic background with huge application in cowpea crop improvement programs across the world

Agro-morphological characterization of lentil germplasm of Indian National Genebank and Development of a core set for efficient utilization in lentil improvement programs

Lentil (Lens culinaris Medik.) is one of the major cool-season pulse crops worldwide. Its increasing demand as a staple pulse has led to the unlocking of diverse germplasm collections conserved in the genebanks to develop its superior varieties. The Indian National Genebank, housed at the Indian Council of Agricultural Research (ICAR)-National Bureau of Plant Genetic Resources, New Delhi, India, currently has 2,324 accessions comprising 1,796 indigenous and 528 exotic collections. This study was conducted to unveil the potential of lentil germplasm by assessing its agro-morphological characteristics and diversity, identifying trait-specific germplasm, and developing a core set. The complete germplasm set was characterized for two years, i.e., 2017-2018 and 2018-2019, and data were recorded on 26 agro-morphological traits. High phenotypic variability was observed for nine quantitative and 17 qualitative traits. A core set comprising 170 accessions (137 Indian and 33 exotic) was derived based on the characterization data as well as geographical origin using a heuristic method and PowerCore software. This core set was found to be sufficiently diverse and representative of the entire collection based on the comparison made using Shannon-Weaver diversity indices and χ2 test. These results were further validated by summary statistics. The core set displayed high genetic diversity as evident from a higher coefficient of variance in comparison to the entire set for individual traits and overall Shannon-Weaver diversity indices (entire: 1.054; core: 1.361). In addition, the total variation explained by the first three principal components was higher in the core set (70.69%) than in the entire collection (68.03%). Further, the conservation of pairwise correlation values among descriptors in the entire and core set reflected the maintenance of the structure of the whole set. Based on the results, this core set is believed to represent the entire collection, completely. Therefore, it constitutes a potential set of germplasm that can be used in the genetic enhancement of lentils