Síndrome de Hoffman: reporte de un caso de miopatía tiroidea

El hipotiroidismo primario constituye el 95% de las insuficiencias tiroideas. Este se presenta con diversas manifestaciones, entre ellas la debilidad simétrica proximal e hipertrofia muscular conocida como síndrome de Hoffman. Dicha patología se reporta únicamente en el 10% de casos, por lo que realizar el diagnóstico diferencial de debilidad muscular es indispensable. A continuación se relata el caso de un paciente de 69 años que consulta por debilidad muscular proximal progresiva, mialgias, dislalia y somnolencia; durante su hospitalización fue diagnosticado con tiroiditis de Hashimoto y miopatía hipotiroidea hipertrófica del adulto

What the neurocognitive study of inner language reveals about our inner space

International audienceOur inner space is furnished, and sometimes even stuffed, with verbal material. The nature of inner language has long been under the careful scrutiny of scholars, philosophers and writers, through the practice of introspection. The use of recent experimental methods in the field of cognitive neuroscience provides a new window of insight into the format, properties, qualities and mechanisms of inner language. Gathering findings from introspection and empirical works, this article first assesses the proportion of language in our inner space. Several variants of inner language are then described, including wilful vs spontaneous instances, condensed vs expanded forms, silent vocalisation during reading or writing, contained vs ruminative occurrences, and self-controlled vs hallucinatory cases. The nature of these variants and their embodied multisensory qualities are examined. Finally, a neurocognitive model of the production of inner language is drawn, in the framework of predictive control, speculating on the neural mechanisms that underlie one of the most significant components of our inner space