Stellar magnetic activity and variability of oscillation parameters - An investigation of 24 solar-like stars observed by Kepler

Context. The Sun and solar-like stars undergo activity cycles for which the underlying mechanisms are not well understood. The oscillations of the Sun are known to vary with its activity cycle and these changes provide diagnostics on the conditions below the photosphere. Kepler has detected oscillations in hundreds of solar-like stars but as of yet, no widespread detection of signatures of magnetic activity cycles in the oscillation parameters of these stars have been reported. Aims. We analyse the photometric short cadence Kepler time series of a set of 24 solar-like stars, which were observed for at least 960 days each, with the aim to find signatures of stellar magnetic activity in the oscillation parameters. Methods. We analyse the temporal evolution of oscillation parameters by measuring mode frequency shifts, changes in the height of the p-mode envelope, as well as granulation time scales. Results. For 23 of the 24 investigated stars, we find significant frequency shifts in time. We present evidence for magnetic activity in six of them. We find that the amplitude of the frequency shifts decreases with stellar age and rotation period. For the most prominent example, KIC 8006161, we find that, similar to the solar case, frequency shifts are smallest for the lowest and largest for the highest p-mode frequencies. Conclusions. These findings show that magnetic activity can be routinely observed in the oscillation parameters for solar-like stars, which opens up the possibility to place the solar activity cycle in the context of other stars by asteroseismology.Comment: 25 pages, 34 figures. Accepted for publication in Astronomy & Astrophysic

The Average-Case Area of Heilbronn-Type Triangles

From among ${n \choose 3}$ triangles with vertices chosen from $n$ points in the unit square, let $T$ be the one with the smallest area, and let $A$ be the area of $T$. Heilbronn's triangle problem asks for the maximum value assumed by $A$ over all choices of $n$ points. We consider the average-case: If the $n$ points are chosen independently and at random (with a uniform distribution), then there exist positive constants $c$ and $C$ such that $c/n^3 < \mu_n < C/n^3$ for all large enough values of $n$, where $\mu_n$ is the expectation of $A$. Moreover, $c/n^3 < A < C/n^3$, with probability close to one. Our proof uses the incompressibility method based on Kolmogorov complexity; it actually determines the area of the smallest triangle for an arrangement in ``general position.''Comment: 13 pages, LaTeX, 1 figure,Popular treatment in D. Mackenzie, On a roll, {\em New Scientist}, November 6, 1999, 44--4

Couples’ dyadic coping in the context of child-related stressors: A systematic review across three decades

The relevance of dyadic coping (DC), a concept how couples cope with stressors together, has been established in different contexts (e.g., daily hassles, mental and physical health) and is related to different outcomes such as relationship satisfaction, relationship quality and stability, psychological well-being, and child behavior. The current systematic review aims at providing an integration of the field of research on couple’s DC with child-related stressors which are understood as demands that arise for couples due to becoming or being parents. DC and related search terms were used for the literature search in PsycINFO, Psyndex, and Medline. We included 55 publications (reporting empirical data on 6,779 couples in total) including quantitative, qualitative, and mixed-methods studies published between 1990 and 2020. We applied a narrative synthesis approach organizing the results around six identified areas of child-related stressors: pregnancy and transition to parenthood, parenting, child mental health, child disability, child chronic physical illness, and child death. Overall, results show the importance of DC for both individual and relationship functioning in the context of child-related stress. Surprisingly, effects of parental DC on child outcomes remained understudied, although the existing studies yield promising results for child adjustment. In conclusion, adapting a “we”-perspective, mutual understanding and support is of importance not only to overcome the stressor but also to grow together as a couple. As DC plays a significant role for couples to cope in a resilient way when facing child-related stressors it should be more promoted in couple- and family counseling and therapy

Dyadic coping and mental health in couples: A systematic review

Globally, one out of three people suffer from a mental health issue during their lifetime. In romantic relationships, impaired mental health does not only affect the individual but also their partner and therefore needs to be coped with dyadically. In this systematic review, we summarize research examining dyadic coping (DC) in the context of mental health and individual and relational outcomes. We searched for peer-reviewed articles published between January 1990 and April 2023 on PsycInfo, Medline, and PSYNDEX on DC and mental health within romantic relationships. A total of 60 qualitative, quantitative, and intervention studies met the inclusion criteria, reporting on 16,394 individuals and 4,945 dyads. To synthesize the studies, we used a narrative synthesis approach. Overall, stress expression and positive DC yielded beneficial individual and relational outcomes, whereas, for negative DC, the opposite was true. Results differed between mental health clusters and context played an important role (e.g., symptom severity, life phase). Due to the great diversity of studies and variables, further research should focus on understudied mental health clusters (e.g., anxiety disorders). Clinicians are advised to view mental health issues as a dyadic rather than an individual phenomenon (“we-disease”) and develop tailored couple-centered interventions

Evaluation of ECHO PS Positioning System in a Porcine Model of Simulated Laparoscopic Ventral Hernia Repair

Purpose. Operative efficiency improvements for laparoscopic ventral hernia repair (LVHR) have focused on reducing operative time while maintaining overall repair efficacy. Our objective was to evaluate procedure time and positioning accuracy of an inflatable mesh positioning device (Echo PS Positioning System), as compared to a standard transfascial suture technique, using a porcine model of simulated LVHR. Methods. The study population consisted of seventeen general surgeons (n = 17) that performed simulated LVHR on seventeen (n = 17) female Yorkshire pigs using two implantation techniques: (1) Ventralight ST Mesh + Echo PS Positioning System (Echo PS) and (2) Ventralight ST Mesh + transfascial sutures (TSs). Procedure time and mesh centering accuracy overtop of a simulated surgical defect were evaluated. Results. Echo PS demonstrated a 38.9% reduction in the overall procedure time, as compared to TS. During mesh preparation and positioning, Echo PS demonstrated a 60.5% reduction in procedure time (P \u3c 0.0001). Although a trend toward improved centering accuracy was observed for Echo PS (16.2%), this was not significantly different than TS. Conclusions. Echo PS demonstrated a significant reduction in overall simulated LVHR procedure time, particularly during mesh preparation/positioning. These operative time savings may translate into reduced operating room costs and improved surgeon/operating room efficiency

Ethanol consumption impairs vestibulo-ocular reflex function measured by the video head impulse test and dynamic visual acuity

Ethanol affects many parts of the nervous system, from the periphery to higher cognitive functions. Due to the established effects of ethanol on vestibular and oculomotor function, we wished to examine its effect on two new tests of the vestibulo-ocular reflex (VOR): the video head impulse test (vHIT) and dynamic visual acuity (DVA). We tested eight healthy subjects with no history of vestibular disease after consumption of standardized drinks of 40% ethanol. We used a repeated measures design to track vestibular function over multiple rounds of ethanol consumption up to a maximum breath alcohol concentration (BrAC) of 1.38‰. All tests were normal at baseline. VOR gain measured by vHIT decreased 25% by the highest BrAC level tested in each subject. Catch-up saccades were negligible at baseline and increased in number and size with increasing ethanol consumption (from 0.13° to 1.43° cumulative amplitude per trial). DVA scores increased by 86% indicating a deterioration of acuity, while static visual acuity (SVA) remained unchanged. Ethanol consumption systematically impaired the VOR evoked by high-acceleration head impulses and led to a functional loss of visual acuity during head movement.NHMR

Effects of Cotton Defoliants on Native Trees in Cotton Production Areas of the Namoi Catchment at Boggabri, NSW, Australia: Field and Glasshouse Experiments

Native tree decline and dieback are issues of general concern in many rural landscapes including cotton production regions of the Namoi Catchment in NSW, Australia. Landholders and cotton producers are interested in the potential effects of cotton defoliants on surrounding native trees via the mechanism of spray drift from cotton defoliation activities; whilst researchers, resource managers and sections of the wider community are keen to define all potential causal agents of the increasing frequency of tree loss in regions of north-western NSW. The aim of this research project was to determine the potential effects of cotton defoliants on localised Australian native tree species from north-western NSW and to assess potential of observed effects to contribute to native tree decline and dieback or act as causal agents of these conditions. Five experiments (three field-based and two glasshouse-based) were designed to test the relative effects of four commercially-applied cotton defoliants (utilised in the Australian cotton industry), including: Dropp Liquid® (thidiazuron, TDZ), Dropp Ultra® (thidiazuron + diuron, TDZ+DN), Prep 720® (ethephon, ETP) and Atlacide® (sodium chlorate, NaCl3). The two major field-based experiments examined the relative effects of annual and periodic exposure of young native trees to defoliants over three years, whilst the third measured the impact of an intentional over-spray during routine, commercial defoliation activities on mature trees (growing in a retained stand)

Neural correlates of individuation and categorization of other-species faces in infancy

The goal of this study was to investigate 9-month-old infants' ability to individuate and categorize other-species faces at the subordinate level. We were also interested in examining the effects of initial exposure conditions on infant categorization and individuation processes. Infants were either familiarized with a single monkey face in an individuation procedure or familiarized with multiple exemplars of monkey faces from the same species in a categorization procedure. Event-related potentials were recorded while the infants were presented: familiar faces, novel faces from the familiar species, or novel faces from a novel species. The categorization group categorized monkey faces by species at the subordinate level, whereas the individuation group did not discriminate monkey faces at the individual or subordinate level. These findings indicate initial exposure to multiple exemplars facilitates infant processing of other-species faces, and infants are efficient at subordinate-level categorization at 9 months of age

Intramuscular Olanzapine and Intramuscular Haloperidol in Acute Schizophrenia: Antipsychotic Efficacy and Extrapyramidal Safety During the First 24 Hours of Treatment

To determine the antipsychotic efficacy and extrapyramidal safety of intramuscular (IM) olanzapine and IM haloperidol during the first 24 hours of treatment of acute schizophrenia. Method: Patients (n = 311) with acute schizophrenia were randomly allocated (2:2: 1) to receive IM olanzapine (10.0 mg, n = 131), IM haloperidol (7.5 mg, n = 126), or IM placebo (n = 54). Results: After the first injection, IM olanzapine was comparable to IM haloperidol and superior to IM placebo for reducing mean change scores from baseline on the Brief Psychiatric Rating Scale (BRPS) Positive at 2 hours (-2.9 olanzapine, -2.7 haloperidol, and -1.5 placebo) and 24 hours (-2.8 olanzapine, -3.2 haloperidol, and -1.3 placebo); the BPRS Total at 2 hours (-14.2 olanzapine,-13.1 haloperidol, and -7.1 placebo) and 24 hours (-12.8 olanzapine, -12.9 haloperidol, and -6.2 placebo); and the Clinical Global Impressions (CGI) scale at 24 hours (-0.5 olanzapine, -0.5 haloperidol, and -0.1 placebo). Patients treated with IM olanzapine had significantly fewer incidences of treatment-emergent parkinsonism (4.3% olanzapine vs 13.3% haloperidol, P = 0.036), but not akathisia (1.1% olanzapine vs 6.5% haloperidol, P = 0.065), than did patients treated with IM haloperidol; they also required significantly less anticholinergic treatment (4.6% olanzapine vs 20.6% haloperidol, P < 0.001). Mean extrapyramidal symptoms (EPS) safety scores improved significantly from baseline during IM olanzapine treatment, compared with a general worsening during IM haloperidol treatment (Simpson-Angus Scale total score mean change: -0.61 olanzapine vs 0.70 haloperidol; P < 0.001; Barnes Akathisia Scale global score mean change: -0.27 olanzapine vs 0.01 haloperidol; P < 0.05). Conclusion: IM olanzapine was comparable to IM haloperidol for reducing the symptoms of acute schizophrenia during the first 24 hours of treatment, the efficacy of both being evident within 2 hours after the first injection. In general, more EPS were observed during treatment with IM haloperidol than with IM olanzapine

Nightly treatment of primary insomnia with prolonged release melatonin for 6 months: a randomized placebo controlled trial on age and endogenous melatonin as predictors of efficacy and safety

&lt;p&gt;Background: Melatonin is extensively used in the USA in a non-regulated manner for sleep disorders. Prolonged release melatonin (PRM) is licensed in Europe and other countries for the short term treatment of primary insomnia in patients aged 55 years and over. However, a clear definition of the target patient population and well-controlled studies of long-term efficacy and safety are lacking. It is known that melatonin production declines with age. Some young insomnia patients also may have low melatonin levels. The study investigated whether older age or low melatonin excretion is a better predictor of response to PRM, whether the efficacy observed in short-term studies is sustained during continued treatment and the long term safety of such treatment.&lt;/p&gt; &lt;p&gt;Methods: Adult outpatients (791, aged 18-80 years) with primary insomnia, were treated with placebo (2 weeks) and then randomized, double-blind to 3 weeks with PRM or placebo nightly. PRM patients continued whereas placebo completers were re-randomized 1:1 to PRM or placebo for 26 weeks with 2 weeks of single-blind placebo run-out. Main outcome measures were sleep latency derived from a sleep diary, Pittsburgh Sleep Quality Index (PSQI), Quality of Life (World Health Organzaton-5) Clinical Global Impression of Improvement (CGI-I) and adverse effects and vital signs recorded at each visit.&lt;/p&gt; &lt;p&gt;Results: On the primary efficacy variable, sleep latency, the effects of PRM (3 weeks) in patients with low endogenous melatonin (6-sulphatoxymelatonin [6-SMT] ≤8 μg/night) regardless of age did not differ from the placebo, whereas PRM significantly reduced sleep latency compared to the placebo in elderly patients regardless of melatonin levels (-19.1 versus -1.7 min; P = 0.002). The effects on sleep latency and additional sleep and daytime parameters that improved with PRM were maintained or enhanced over the 6-month period with no signs of tolerance. Most adverse events were mild in severity with no clinically relevant differences between PRM and placebo for any safety outcome.&lt;/p&gt; &lt;p&gt;Conclusions: The results demonstrate short- and long-term efficacy and safety of PRM in elderly insomnia patients. Low melatonin production regardless of age is not useful in predicting responses to melatonin therapy in insomnia. The age cut-off for response warrants further investigation.&lt;/p&gt