Ecdysteroids. Selective Protections and Synthesis of Potential Tools for Biochemical Studies

B-Ecdysone and cyasterone bave been transformed into the ecdysterone analogue 4, wbich carries a [3-(p-hydroxyphenyl).-propoxylj- group at the end of the side chain. This derivative should be useful for various biochemical investigations (I-labelling, affinity chromatography), since it exhibits a marked ecdysterone-like activity in two independent biological tests. The synthetic scheme makes use of highly selective protections of the hydroxyl groups of phytoecdysteroids

De l'origine des pétroles à celle de la vie cellulaire

Ourisson Guy. De l'origine des pétroles à celle de la vie cellulaire. In: Bulletin de la Classe des sciences, tome 9, n°1-6, 1998. pp. 131-132