The trajectory of mental health problems for UK emerging adults during COVID-19

Initial COVID-19 restrictions were associated with declining mental health, particularly in UK emerging adults. Prior research has yet to examine changes in mental health in this demographic over the entire course of the three UK national lockdowns. Drawing upon the Understanding Society COVID-19 Survey, this study examined the trajectory of mental health problems for emerging adults (18-29-year-olds) from April 2020–September 2021. Mental health problems were assessed at nine time-points using the General Health Questionnaire. The analytic sample included 1018 participants (304 males, 714 females). Growth curve modelling was used to examine the trajectory of mental health problems and the associated sociodemographic and health covariates. Females and those with fewer household members, lower income, no private garden, and pre-existing mental or physical health diagnoses reported more mental health problems. Gender differences were evident in the rate of change. Females' mental health problems declined from the first lockdown until just after the relaxation of initial restrictive measures (September 2020), increased until April 2021 (constituting lockdowns two and three), and then slightly decreased until September 2021 during the phased exit from restrictions. Males’ mental health problems followed a similar trajectory, with a greater rate of increase in mental health problems from July 2020–April 2021, and a greater rate of decline from April–September 2021. Females reported more mental health problems throughout the three national lockdowns than males. These findings can inform public health policies targeted toward young adult populations and highlight sub-populations at greater risk of worsening mental health

Trajectories of physical activity during COVID-19: A longitudinal analysis of UK young adults

Research has demonstrated a disproportionate reduction in the moderate-vigorous physical activity (MVPA) of young UK adults during the initial months of COVID-19. However, previous research has not examined the trajectory of MVPA for this demographic over subsequent phases of the pandemic. The present study investigated the trajectory of MVPA from April 2020 to January 2021 in young UK adults. Data were drawn from 18-29-year-old participants of the Understanding Society COVID-19 Survey (212 males, 542 females). Weekly MVPA was self-reported at three time points (April and September 2020; January 2021) using the International Physical Activity Questionnaire. After controlling for significant covariates, growth curve modelling revealed no variation in weekly MVPA, which remained higher than the UK Physical Activity Guidelines. Female gender; Asian, Black and Mixed ethnicity; lower income,; living with a partner; and no access to a private garden or other outdoor space were associated with lower MVPA in April 2020. Gender, however, was a significant moderator of the trajectory. Males’ MVPA increased between April 2020 to August 2020, followed by a sharp decline; whereas females showed a steady rate of decline from April 2020 to January 2021. Despite the recurrent lockdowns, this study shows that young UK adults, on average, continued to engage in MVPA, above the recommendated amount. Nevertheless, significant variation associated with gender, ethnicity and income highlights the importance of providing accessible spaces for young adults to exercise, especially those with limited access to private gardens

Serological evidence of cross infection in a dialysis unit hepatitis-B epidemic

Serological evidence of cross infection in a dialysis unit hepatitis-B epidemic. This study provides serological as well as epidemiological evidence that a dialysis unit hepatitis-B epidemic was spread by cross contamination. There were 74 patients and staff who developed HB-Ag-positive hepatitis during a 28-month hospital surveillance period. Twenty-six of these cases were intimately related to the dialysis unit (21 dialysis/transplant patients and five hospital staff) and 58 were not. Representative sera from each group of cases were further tested for HB-Ag subtype specificity. Thirteen of 14 dialysis/transplant patients had subtype ay whereas ten of 15 general hospital patients had the alternate phenotype ad. All four staff who had probably acquired their infection from dialysis/transplant patients were ay subtype. Eight of the dialysis/transplant patients had never received blood. Transfusion rate in the infected dialysis patients was one-third that of leukemic patients but the hepatitis rate was higher.Preuve sérologique d'une contamination croisée dans une unité de dialyse par le virus B de l'hépatite. Ce travail apporte les preuves sérologiques et épidémiologiques de la contamination croisée d'une unité d'hémodialyse par le virus B de l'hépatite. Soixante-quatorze malades et membres de l'équipe ont développé une hépatite HB-Ag positive dans les 28 mois de la surveillance de l'hôpital. Vingt-six de ces cas ont été liés étroitement à la dialyse (21 malades de dialyse ou transplantation et 5 membres de l'équipe) et 58 ne l'étaient pas. Dans chaque groupe de cas le sérum a été étudié pour identifier les phénotypes de HB-Ag. Treize des 14 malades de dialyse ou transplantation avaient le phénotype ay alors que 10 parmi 15 des malades de l'hôpital général avaient l'autre phénotype ad. Les quatre membres de l'équipe qui avaient probablement contracté leur infection à partir de malades de transplantation ou de dialyse avaient le phénotype ay. Huit des malades de dialyse ou de transplantation n'avaient jamais reçu de sang. Le débit transfusions chez les malades en dialyse atteints par l'hépatite était le tiers de celui des malades leucémiques mais l'incidence de l'hépatite a été plus grande chez les premiers

La transferencia tecnológica en los orígenes de la moderna biotecnología en Argentina: el caso de la articulación de Zelltek con la Universidad Nacional del Litoral.

El objetivo del presente artículo es analizar los cambios operados en la relación universidad empresa la integración de la empresa Zelltek, una empresa de biotecnología incubada en al UNL, al grupo Amega Biotech. En particular discutimos qué cambios se registraron en la relación, en términos institucionales, organizacionales y sociales así como en la forma en que se crean capacidades a partir de la interacción.publishedVersio

Cardiac outcomes 12 months post percutaneous coronary intervention

Cardiovascular disease (CVD) has over the last decade emerged as the single most important cause for death worldwide [1]. Percutaneous coronary intervention (PCI) is a very common revascularisation procedure for coronary artery disease (CAD). Despite advancement in surgical technology, PCI is associated with a range of post-procedural complications, including physical [2] and psychological morbidity [3]. Research findings are inconclusive as to the impact of PCI on quality of life post-procedure. There also appears to be no studies that have examined the notion of personal resilience in this group of patients. The aim of this longitudinal prognostic study was to evaluate cardiac outcomes including - health related quality of life (HRQoL), personal resilience, mental health and adherence behaviours in patients who have had undergone a PCI measured at two time points (6 months and 12 months) post-intervention

Dimensiones conceptuales para el estudio de clusters de alta tecnología

En el presente capítulo, a partir de los aportes de la literatura especializada en esta temática, nos proponemos avanzar en respuestas a estos interrogantes, con el propósito de delinear un marco conceptual que permita analizar la concentración espacial de actividades industriales y de servicios basadas en el conocimiento científico en países en desarrollo y, en particular, en Argentina. En esta dirección, se discuten algunos aspectos teóricos e históricos destacados por la literatura para la comprensión del surgimiento de clusters de alta tecnología, poniendo el acento en los sectores de la moderna biotecnología (MB) aplicada a salud humana, y en software y servicios informáticos (SSI) como uno de los subsectores de las tecnologías de la información y comunicación. El foco en estas tecnologías se vincula con el objetivo central de este libro, que es el análisis de casos de clusters (o proto-clusters) tecnológicos basados en estas tecnologías en Argentina. La revisión conceptual se centrará en las categorías de clusters tecnológicos y de sistemas locales, regionales y nacionales de innovación, con énfasis en las modalidades de articulación universidad/empresa2. Por último, se discute la pertinencia de estas propuestas para el análisis de estos procesos en países en desarrollo.Fil: Gutman, Graciela Elena. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Saavedra 15. Centro de Estudios Urbanos y Regionales; ArgentinaFil: Gorenstein, Silvia Mirta. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Saavedra 15. Centro de Estudios Urbanos y Regionales; ArgentinaFil: Robert, Veronica. Universidad Nacional de San Martin. Escuela de Economía y Negocios; Argentina. Universidad Nacional de General Sarmiento; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentin