Active core rewarming avoids bioelectrical impedance changes in postanesthetic patients

<p>Abstract</p> <p>Background</p> <p>Postoperative hypothermia is a common cause of complications in patients who underwent laparoscopic cholecystectomy. Hypothermia is known to elicit electrophysiological, biochemical, and cellular alterations thus leading to changes in the active and passive membrane properties. These changes might influence the bioelectrical impedance (BI). Our aim was to determine whether the BI depends on the core temperature.</p> <p>Methods</p> <p>We studied 60 patients (52 female and 8 male) age 40 to 80 years with an ASA I-II classification that had undergone laparoscopic cholecystectomy under balanced inhalation anesthesia. The experimental group (<it>n </it>= 30) received active core rewarming during the transanesthetic and postanesthesic periods. The control group (<it>n </it>= 30) received passive external rewarming. The BI was recorded by using a 4-contact electrode system to collect dual sets of measurements in the deltoid muscle. The body temperature, hemodynamic variables, respiratory rate, blood-gas levels, biochemical parameters, and shivering were also measured. The Mann-Whitney unpaired <it>t</it>-test was used to determine the differences in shivering between each group at each measurement period. Measurements of body temperature, hemodynamics variables, respiratory rate, and BI were analyzed using the two-way repeated-measures ANOVA.</p> <p>Results</p> <p>The gradual decrease in the body temperature was followed by the BI increase over time. The highest BI values (95 ± 11 Ω) appeared when the lowest values of the temperature (35.5 ± 0.5°C) were reached. The active core rewarming kept the body temperature within the physiological range (over 36.5°C). This effect was accompanied by low stable values (68 ± 3 Ω) of BI. A significant decrease over time in the hemodynamic values, respiratory rate, and shivering was seen in the active core-rewarming group when compared with the controls. The temporal course of shivering was different from those of body temperatue and BI. The control patients showed a significant increase in the serum-potassium levels, which were not seen in the active-core rewarming group.</p> <p>Conclusions</p> <p>The BI analysis changed as a function of the changes of core temperature and independently of the shivering. In addition, our results support the beneficial use of active core rewarming to prevent accidental hypothermia.</p

EDUCACIÓN AMBIENTAL Y SOCIEDAD. SABERES LOCALES PARA EL DESARROLLO Y LA SUSTENTABILIDAD

Este texto contribuye al análisis científico de varias áreas del conocimiento como la filosofía social, la patología, la educación para el cuidado del medio ambiente y la sustentabilidad que inciden en diversas unidades de aprendizaje de la Licenciatura en Educación para la Salud y de la Maestría en Sociología de la SaludLas comunidades indígenas de la sierra norte de Oaxaca México, habitan un territorio extenso de biodiversidad. Sin que sea una área protegida y sustentable, la propia naturaleza de la región ofrece a sus visitantes la riqueza de la vegetación caracterizada por sus especies endémicas que componen un paisaje de suma belleza

Descubrimiento de conocimiento en incidencia de tipo de cáncer para pacientes terminales mediante minería de datos

"Se analiza la incidencia del tipo de cáncer y sus principales manifestaciones en la etapa terminal mediante la minería de datos. Se analizaron 288 datos de 22 pacientes, los cuales proporcionó la unidad de cuidados paliativos del Hospital Regional 1° d

Descubrimiento de conocimiento en incidencia de tipo de cáncer para pacientes terminales mediante minería de datos

The objective of this work is to analyze the incidence of the type of cancer and its main manifestations in the terminal stage through data mining. We analyzed 288 data from 22 patients, provided by the Palliative Care Unit of the Hospital Regional 1 de Octubre. The evaluated variables were gender, year, age, diagnosis and symptom. The algorithm J48 corresponding to the algorithm C4.5 was used for the classification. The highest incidence of mortality according to the type of cancer is highlighted: lung, colon, rectum, breast and prostate. As for pain, it is higher in young patients, while in patients aged 65 or less, 39% and only 23% of the rest.Se analiza la incidencia del tipo de cáncer y sus principales manifestaciones en la etapa terminal mediante la minería de datos. Se analizaron 288 datos de 22 pacientes, los cuales proporcionó la unidad de cuidados paliativos del Hospital Regional 1° de Octubre. Las variables evaluadas fueron género, año, edad, diagnóstico y síntoma. Para la clasificación se utilizó el algoritmo J48 correspondiente al algoritmo C4.5. La mayor incidencia de mortalidad, de acuerdo con el tipo de cáncer, se da en el de pulmón, colon, recto, mama y el de próstata. En cuanto al dolor, se presenta en mayor medida en pacientes jóvenes, mientras que en pacientes de 65 años o menos 39% y sólo en 23% de los restantes

Descubrimiento de conocimiento en incidencia de tipo de cáncer para pacientes terminales mediante minería de datos

The objective of this work is to analyze the incidence of the type of cancer and its main manifestations in the terminal stage through data mining. We analyzed 288 data from 22 patients, provided by the Palliative Care Unit of the Hospital Regional 1 de Octubre. The evaluated variables were gender, year, age, diagnosis and symptom. The algorithm J48 corresponding to the algorithm C4.5 was used for the classification. The highest incidence of mortality according to the type of cancer is highlighted: lung, colon, rectum, breast and prostate. As for pain, it is higher in young patients, while in patients aged 65 or less, 39% and only 23% of the restSe analiza la incidencia del tipo de cáncer y sus principales manifestaciones en la etapa terminal mediante la minería de datos. Se analizaron 288 datos de 22 pacientes, los cuales proporcionó la unidad de cuidados paliativos del Hospital Regional 1° de Octubre. Las variables evaluadas fueron género, año, edad, diagnóstico y síntoma. Para la clasificación se utilizó el algoritmo J48 correspondiente al algoritmo C4.5. La mayor incidencia de mortalidad, de acuerdo con el tipo de cáncer, se da en el de pulmón, colon, recto, mama y el de próstata. En cuanto al dolor, se presenta en mayor medida en pacientes jóvenes, mientras que en pacientes de 65 años o menos 39% y sólo en 23% de los restantes

Reproducibility of fluorescent expression from engineered biological constructs in E. coli

We present results of the first large-scale interlaboratory study carried out in synthetic biology, as part of the 2014 and 2015 International Genetically Engineered Machine (iGEM) competitions. Participants at 88 institutions around the world measured fluorescence from three engineered constitutive constructs in E. coli. Few participants were able to measure absolute fluorescence, so data was analyzed in terms of ratios. Precision was strongly related to fluorescent strength, ranging from 1.54-fold standard deviation for the ratio between strong promoters to 5.75-fold for the ratio between the strongest and weakest promoter, and while host strain did not affect expression ratios, choice of instrument did. This result shows that high quantitative precision and reproducibility of results is possible, while at the same time indicating areas needing improved laboratory practices.Peer reviewe