Effects of chronic stress on the activity of ATP-AZ in cells of immune response in rats and correcting the possibility of internal energy exchange reception mineral water

Zmievsky A. V., Nasibullin B. A., Guscha S. G. Влияние хронического стресса на активность системы АТФ-АЗ в клетках иммунного ответа у крыс, и возможность коррекции нарушений энергетического обмена внутренним приёмом минеральных вод = Effects of chronic stress on the activity of ATP-AZ in cells of immune response in rats and correcting the possibility of internal energy exchange reception mineral water. Journal of Education, Health and Sport. 2015;5(4):129-134. ISSN 2391-8306. DOI: 10.5281/zenodo.16686 http://ojs.ukw.edu.pl/index.php/johs/article/view/2015%3B5%284%29%3A129-134 https://pbn.nauka.gov.pl/works/553740 http://dx.doi.org/10.5281/zenodo.16686 Formerly Journal of Health Sciences. ISSN 1429-9623 / 2300-665X. Archives 2011 – 2014 http://journal.rsw.edu.pl/index.php/JHS/issue/archive   Deklaracja. Specyfika i zawartość merytoryczna czasopisma nie ulega zmianie. Zgodnie z informacją MNiSW z dnia 2 czerwca 2014 r., że w roku 2014 nie będzie przeprowadzana ocena czasopism naukowych; czasopismo o zmienionym tytule otrzymuje tyle samo punktów co na wykazie czasopism naukowych z dnia 31 grudnia 2014 r. The journal has had 5 points in Ministry of Science and Higher Education of Poland parametric evaluation. Part B item 1089. (31.12.2014). © The Author (s) 2015; This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland and Radom University in Radom, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 20.01.2014. Revised 27.03.2015. Accepted: 27.03.2015.   Влияние хронического стресса на активность системы АТФ-аз в клетках иммунного ответа у крыс, и возможность коррекции нарушений энергетического обмена внутренним приёмом минеральных вод EFFECTS OF CHRONIC STRESS ON THE ACTIVITY OF ATP-AZ IN CELLS OF IMMUNE RESPONSE IN RATS AND CORRECTING THE POSSIBILITY OF INTERNAL ENERGY EXCHANGE RECEPTION MINERAL WATER   А.В. Змиевский, Б.А. Насибуллин, С.Г. Гуща A.V. Zmievsky, B.A. Nasibullin, S.G. Guscha   Украинский научно-исследовательский институт медицинской реабилитации и курортологии МЗ Украины, Одесса Ukrainian Research Institute of Medical Rehabilitation and Balneology, Odessa   Abstract   The authors of the model when playing immobilization - emotional stress in animals have revealed abnormalities in energy supply in the organs of the immune response. The authors demonstrated the possibility of correction of stress caused by disorders of energy metabolism in thymocytes and splenocytes using the mineral waters of different chemical composition.   Keywords: energy metabolism, mineral water, thymocytes, splenocytes.   Реферат Авторы при воспроизведении модели иммобилизационно-эмоционального стресса у животных выявили нарушения в энергообеспечении в органах иммунного ответа. Авторами была показана возможность коррекции стресс-обусловленных нарушений энергетического обмена в тимоцитах и спленоцитах при помощи минеральных вод разного химического состава.   Ключевые слова: энергетический обмен, минеральные воды, тимоциты, спленоциты

Complex Estimation of Functional Changes in the Organism of Healthy Rats Which Consumed Water of the Lake Kagul as Drinking Water.

In the work results of a complex estimation of functional changes in an organism of healthy rats which consumed water of the lake of Kagul as drinking water are given. Conformity of water of the lake of Kagul to requirements of operating standard documents except for nitrogen ammonia, nitrogen nitrit and the general organic carbon is established. 3 kinds of cyanobacteriaе, in particular high levels of Aphanocapsa pulverea, which causes water "flowering" are revealed. It is shown that the use of water of the lake of Kagul as drinking, causes strengthening of activity of central nervous system in healthy rats; some increase of possibilities of organism sensitisation development and specific phagocytosis, certain displays of disbalance of hummoral component of the immune response and expansion of autoimmune processes in the organism. In the view of absence of hyginicaly significant concentration of anthropogenous pollutants, the idea that the revealed biological effects are a consequence of cyanotoxins action produced by revealed cyanobacteriaе is presented. Necessity of expansion and continuation of researches on cyanobacteriaе in the context of their revealing in water, their identifications, influences of these xenobiotics on condition of warm-blooded animals and the human is proved

Комплексная оценка функциональных изменений в организме здоровых крыс, которые потребляли в качестве питьевой воду оз. Кагул

In the work results of a complex estimation of functional changes in an organism of healthy rats which consumed water of the lake of Kagul as drinking water are given. Conformity of water of the lake of Kagul to requirements of operating standard documents except for nitrogen ammonia, nitrogen nitrit and the general organic carbon is established. 3 kinds of cyanobacteriae, in particular high levels of Aphanocapsa pulverea, which causes water "flowering" are revealed. It is shown that the use of water of the lake of Kagul as drinking, causes strengthening of activity of central nervous system in healthy rats; some increase of possibilities of organism sensitisation development and specific phagocytosis, certain displays of disbalance of hummoral component of the immune response and expansion of autoimmune processes in the organism. In the view of absence of hyginicaly significant concentration of anthropogenous pollutants, the idea that the revealed biological effects are a consequence of cyanotoxins action produced by revealed cyanobacteriae is presented. Necessity of expansion and continuation of researches on cyanobacteriae in the context of their revealing in water, their identifications, influences of these xenobiotics on condition of warm-blooded animals and the human is proved.В работе приведены результаты комплексной оценки функциональных изменений в организме здоровых крыс, которые потребляли воду озера Кагул в качестве питьевой воды. Установлено соответствие воды озера Кагул требованиям действующих нормативных документов, за исключением азота аммонийного, азота нитритного и общего органического углерода. Выявлено 3 вида цианобактерий, в частности высокие уровени Aphanocapsa pulverea, которые вызывают «цветение» воды. Показано, что употребление воды озера Кагул как питьевой вызывает у здоровых крыс усиление активности ЦНС; некоторое повышение возможностей развития сенсибилизации организма и специфического фагоцитоза, определенные проявления дисбаланса гуморальной составляющей иммунного ответа и развертывание аутоиммунных процессов в организме