968 research outputs found

    Exploration and Production Thesaurus : its helpfulness in indexing in a Library and information System

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    Exploration and Production (E & P) thesaurus published by the Information Service Department, University of Tulsa, is one of the most comprehensive thesaurus in its coverage on the exploration, development and production of crude oil and natural gas. The thesaurus is in continuous use in the Library of the Oil and Natural Gas Commission for indexing the literature and in the development of special schemes of classification for local use. The paper indicates the usefulness of the thesaurus for indexing the entries covered in the various bibliographies and for the preparation of a special scheme of classification for Exploration Geophysic

    Formulation and Evaluation of Orodispersible Tablet of Atorvastatin Calcium by Using Hibiscus rosa sinesis Mucilage as Natural Superdisintegrant

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    Orodispersible tablets (ODTs), also known as fast melt, quick melts, fast disintegrating have the unique property of disintegrating in the mouth in seconds without chewing and the need of water. Oral bioavailability of Atorvastatin Calcium is low (14%) and shows extensive intestinal clearance and first-pass metabolism, which is the main cause for the low systemic availability. In the present work, orodispersible tablets of Atorvastatin calcium were prepared by direct compression method using Hibiscus rosa sinesis mucilage as natural superdisintegrant with a view to enhance patient compliance and to avoid hepatic first pass metabolism and to improve its bioavailability. The prepared batches of tablets were evaluated for hardness, friability, drug content uniformity, wetting time, water-absorption ratio and in-vitro dispersion time. Short-term stability studies on the promising formulation indicated that there are no significant changes in drug content and in vitro dispersion time. Keywords: Orodispersible tablet, Atorvastatin Calcium, lipid-lowering agent, Superdisintegrant, Hibiscus Rosa Sinensis, Bioavailability, solubility.&nbsp

    Have we succeeded in controlling anaemia in pregnancy - a prospective study at tertiary care center

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    Background: WHO has accepted up to 11 gm% as the normal haemoglobin level in pregnancy. Therefore any haemoglobin level below 11 gm% in pregnancy should be considered as anaemia. Objective of current study was to determine prevalence of anaemia in pregnancy and various associated sociodemographic factors.Method: A prospective study was carried out at GSVM Medical College, Kanpur during period Jan 2013 to August 2014. During this period all antenatal patients (4300) who came in outdoor and indoor were included in the study. Prevalence of anaemia among them and its associated sociodemographic factors were studied.Result: In the current study we found the prevalence of anaemia in pregnant females was 92% of which most were moderately anemic (70%) and belonged to age group 24-28 years of age, of higher parity, were of low socioeconomic status(80%), illiterate and from rural areas (54.4%). Anaemia was more prevalent in early age group because of early marriages & in late age group because of multiple birthsConclusion: Despite of various National Nutritional Anaemia Prophylaxix programme in India, anaemia is still a significant challenge during pregnancy presenting mother and fetus at a greater risk of maternal and perinatal mortality and morbidity

    Perturbative quantum gauge invariance: Where the ghosts come from

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    A condensed introduction to quantum gauge theories is given in the perturbative S-matrix framework; path integral methods are used nowhere. This approach emphasizes the fact that it is not necessary to start from classical gauge theories which are then subject to quantization, but it is also possible to recover the classical group structure and coupling properties from purely quantum mechanical principles. As a main tool we use a free field version of the Becchi-Rouet-Stora-Tyutin gauge transformation, which contains no interaction terms related to a coupling constant. This free gauge transformation can be formulated in an analogous way for quantum electrodynamics, Yang-Mills theories with massless or massive gauge bosons and quantum gravity.Comment: 28 pages, LATEX. Some typos corrected, version to be publishe

    Aspects of electrostatics in a weak gravitational field

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    Several features of electrostatics of point charged particles in a weak, homogeneous, gravitational field are discussed using the Rindler metric to model the gravitational field. Some previously known results are obtained by simpler and more transparent procedures and are interpreted in an intuitive manner. Specifically: (i) We show that the electrostatic potential of a charge at rest in the Rindler frame is expressible as A_0=(q/l) where l is the affine parameter distance along the null geodesic from the charge to the field point. (ii) We obtain the sum of the electrostatic forces exerted by one charge on another in the Rindler frame and discuss its interpretation. (iii) We show how a purely electrostatic term in the Rindler frame appears as a radiation term in the inertial frame. (In part, this arises because charges at rest in a weak gravitational field possess additional weight due to their electrostatic energy. This weight is proportional to the acceleration and falls inversely with distance -- which are the usual characteristics of a radiation field.) (iv) We also interpret the origin of the radiation reaction term by extending our approach to include a slowly varying acceleration. Many of these results might have possible extensions for the case of electrostatics in an arbitrary static geometry. [Abridged Abstract]Comment: 26 pages; accepted for publication in Gen.Rel.Gra

    Medical Store Management: An Integrated Economic Analysis of a Tertiary Care Hospital in Central India

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    Economic analysis plays a pivotal role in the management of medical store. The main objectives of this study were to consider always better control-vital, essential and desirable (ABC-VED) analysis with economic order quantity (EOQ), comparison of indexed cost and the actual cost, and to assess the expenditure for the forthcoming years. Based on cost and criticality, a matrix of nine groups by combining ABC and VED analysis was formulated. Drug categories were narrowed down for prioritization to direct supervisory monitoring. The subgroups AE and AV of the categories category I and II should be ordered based on EOQ. The difference between the actual annual drug expenditure (ADE) and the derived indexed cost using the cost inflation index (CII) was calculated. Linear regression was used to assess the expenditure for the forth coming years. The total ADE for the financial year of 2010–2011 was Rs. 1,91,44,253 which was only 7.68% of annual hospital expenditure. Using the inflation index, the indexed cost of acquisition of ADE for year 2010–2011 was Rs. 1,95,10,387. The difference between the two was estimated to be 2.11%. Thus, the CII justifies the demand of increased budget for next year and prompts us for cautious use of drugs. By taking into consideration the ADE of last 10 years, we have forecasted the budget for forthcoming years which will help significantly for making policies according to the available budget

    A Pearson-Dirichlet random walk

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    A constrained diffusive random walk of n steps and a random flight in Rd, which can be expressed in the same terms, were investigated independently in recent papers. The n steps of the walk are identically and independently distributed random vectors of exponential length and uniform orientation. Conditioned on the sum of their lengths being equal to a given value l, closed-form expressions for the distribution of the endpoint of the walk were obtained altogether for any n for d=1, 2, 4 . Uniform distributions of the endpoint inside a ball of radius l were evidenced for a walk of three steps in 2D and of two steps in 4D. The previous walk is generalized by considering step lengths which are distributed over the unit (n-1) simplex according to a Dirichlet distribution whose parameters are all equal to q, a given positive value. The walk and the flight above correspond to q=1. For any d >= 3, there exist, for integer and half-integer values of q, two families of Pearson-Dirichlet walks which share a common property. For any n, the d components of the endpoint are jointly distributed as are the d components of a vector uniformly distributed over the surface of a hypersphere of radius l in a space Rk whose dimension k is an affine function of n for a given d. Five additional walks, with a uniform distribution of the endpoint in the inside of a ball, are found from known finite integrals of products of powers and Bessel functions of the first kind. They include four different walks in R3 and two walks in R4. Pearson-Liouville random walks, obtained by distributing the total lengths of the previous Pearson-Dirichlet walks, are finally discussed.Comment: 33 pages 1 figure, the paper includes the content of a recently submitted work together with additional results and an extended section on Pearson-Liouville random walk

    Search for R-Parity Violating Decays of Scalar Fermions at LEP

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    A search for pair-produced scalar fermions under the assumption that R-parity is not conserved has been performed using data collected with the OPAL detector at LEP. The data samples analysed correspond to an integrated luminosity of about 610 pb-1 collected at centre-of-mass energies of sqrt(s) 189-209 GeV. An important consequence of R-parity violation is that the lightest supersymmetric particle is expected to be unstable. Searches of R-parity violating decays of charged sleptons, sneutrinos and squarks have been performed under the assumptions that the lightest supersymmetric particle decays promptly and that only one of the R-parity violating couplings is dominant for each of the decay modes considered. Such processes would yield final states consisting of leptons, jets, or both with or without missing energy. No significant single-like excess of events has been observed with respect to the Standard Model expectations. Limits on the production cross- section of scalar fermions in R-parity violating scenarios are obtained. Constraints on the supersymmetric particle masses are also presented in an R-parity violating framework analogous to the Constrained Minimal Supersymmetric Standard Model.Comment: 51 pages, 24 figures, Submitted to Eur. Phys. J.
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