Perspective-shifts in event descriptions in Tamil child language

Children are able to take multiple perspectives in talking about entities and events. But the nature of children's sensitivities to the complex patterns of perspective-taking in adult language is unknown. We examine perspective-taking in four- and six-year-old Tamil-speaking children describing placement events, as reflected in the use of a general placement verb (veyyii ‘put’) versus two fine-grained caused posture expressions specifying orientation, either vertical (nikka veyyii ‘make stand’) or horizontal (paDka veyyii ‘make lie’). We also explore whether animacy systematically promotes shifts to a fine-grained perspective. The results show that four- and six-year-olds switch perspectives as flexibly and systematically as adults do. Animacy influences shifts to a fine-grained perspective similarly across age groups. However, unexpectedly, six-year-olds also display greater overall sensitivity to orientation, preferring the vertical over the horizontal caused posture expression. Despite early flexibility, the factors governing the patterns of perspective-taking on events are undergoing change even in later childhood, reminiscent of U-shaped semantic reorganizations observed in children's lexical knowledge. The present study points to the intriguing possibility that mechanisms that operate at the level of semantics could also influence subtle patterns of lexical choice and perspective-shifts

The nature of the [C ii] emission in dusty star-forming galaxies from the SPT survey

We present [C ii] observations of 20 strongly lensed dusty star-forming galaxies at 2.1 20 mJy) from the South Pole Telescope (SPT) survey, with far-infrared (FIR) luminosities determined from extensive photometric data. The [C ii] line is robustly detected in 17 sources, all but one being spectrally resolved. 11 out of 20 sources observed in [C ii] also have low-J CO detections from Australia Telescope Compact Array. A comparison with mid- and high-J CO lines from Atacama Large Millimeter/submillimeter Array reveals consistent [C ii] and CO velocity profiles, suggesting that there is little differential lensing between these species. The [C ii], low-J CO and FIR data allow us to constrain the properties of the interstellar medium. We find [C ii] to CO(1–0) luminosity ratios in the SPT sample of 5200 ± 1800, with significantly less scatter than in other samples. This line ratio can be best described by a medium of [C ii] and CO emitting gas with a higher [C ii] than CO excitation temperature, high CO optical depth τ_CO(1–0) ≫ 1, and low to moderate [C ii] optical depth τ_[CII]≲ 1. The geometric structure of photodissociation regions allows for such conditions

The extostosin family: Proteins with many functions

Heparan sulfates are complex sulfated molecules found in abundance at cell surfaces and in the extracellular matrix. They bind to and influence the activity of a variety of molecules like growth factors, proteases and morphogens and are thus involved in various cell–cell and cell–matrix interactions. The mammalian EXT proteins have glycosyltransferase activities relevant for HS chain polymerization, however their exact role in this process is still confusing. In this review, we summarize current knowledge about the biochemical activities and some proposed functions of the members of the EXT protein family and their roles in human disease.publishedVersio

Exploring the environment, magnetic fields, and feedback effects of massive high-redshift galaxies with [CII]

Massive galaxies are expected to grow through different transformative evolutionary phases where high-redshift starburst galaxies and quasars are examples of such phases. The physical mechanisms driving these phases include companion galaxy interactions, active galactic nuclei feedback, and magnetic fields. Our aim is to characterize the physical properties and the environment of the submillimeter galaxy AzTEC-3 at z = 5.3 and the lensed quasar BRI 0952-0115 at z = 4.4, to set a limit on the polarization properties, as well as placing both in the broader context of galaxy evolution. We used full polarization, sub-arcsecond-resolution, ALMA band-7 observations of both BRI 0952-0115 and AzTEC-3 and detect [CII] line emission towards both galaxies, along with companions in each field. We present an updated gravitational lensing model for BRI 0952-0115. We present infrared luminosities, star-formation rates, and [CII] line to infrared luminosity ratios for each source. The [CII] emission line profile for both BRI 0952-0115 and AzTEC-3 exhibit a broad, complex morphology, indicating the possible presence of outflows. We present evidence of a 'gas bridge' between AzTEC-3 and a companion source. Using a simple dynamical mass estimate for the sources, we suggest that both systems are undergoing minor or major mergers. No polarization is detected for the [CII], placing an upper limit below that of theoretical predictions. Our results show that high-velocity wings are detected, indicating possible signs of massive outflows; however, the presence of companion galaxies can affect the final interpretation. Furthermore, the results provide additional evidence in support of the hypothesis that massive galaxies form in overdense regions, growing through interactions. Finally, strong, ordered magnetic fields are unlikely to exist at the kiloparsec scale in the two studied sources

Iterative 4D reconstruction of dynamic SPECT images

[Abstract] The 22nd International Congress and Exhibition, Barcelona, Spain, June 25-28, 2008The present work presents a new approach for the 4D reconstruction algorithm for dynamic SPECT in a parallel ray geometry based on B-splines including attenuation map from CT and geometry efficiency correction. In this work we make use of 4 piecewise piecewise quadratic temporal splines and a reconstruction algorithm based on the iterative maximization of Poisson likelihood. Results on a Tecnetium (99mTc-Teboroxime) canine study are shownPublicad

Statistical 4D reconstruction of dynamic CT images: preliminary results

[Poster] 4th European Molecular Imaging Meeting, Barcelona, Spain, May 27 - 30, 2009Preliminary results are presented of a 4d reconstruction algorithm for dynamic contrast enhanced CT, in a micro-CT based on cone beam geometry. The method is based on modelling the spatial and temporal distribution of the contrast inside the field of view. The use of non-uniform time sampling with b-splines yielded smooth time-activity curves that captured the relatively fast rise and fall of contrast in the aorta, as well as the uptake and retention of contrast in the kidneysThis work is supported by Ministerio de Ciencia e innovación (TeC2008-06715-C02-01 and TeC2007-64731/TCM), Ministerio de industria (CdTeaM, Programa CeniT), and the reCaVa-reTiC network.Publicad

Pregnancy and childbirth in English prisons : institutional ignominy and the pains of imprisonment

© 2020 The Authors. Sociology of Health & Illness published by John Wiley & Sons Ltd on behalf of Foundation for SHIL.With a prison population of approximately 9000 women in England, it is estimated that approximately 600 pregnancies and 100 births occur annually. Despite an extensive literature on the sociology of reproduction, pregnancy and childbirth among women prisoners is under‐researched. This article reports an ethnographic study in three English prisons undertaken in 2015‐2016, including interviews with 22 prisoners, six women released from prison and 10 staff members. Pregnant prisoners experience numerous additional difficulties in prison including the ambiguous status of a pregnant prisoner, physical aspects of pregnancy and the degradation of the handcuffed or chained prisoner during visits to the more public setting of hospital. This article draws on Erving Goffman's concepts of closed institutions, dramaturgy and mortification of self, Crewe et al.'s work on the gendered pains of imprisonment and Crawley's notion of ‘institutional thoughtlessness’, and proposes a new concept of institutional ignominy to understand the embodied situation of the pregnant prisoner.Peer reviewe