18 research outputs found

    Genesis Mechanism of Deep Carbonate Reservoir in Jizhong Depression

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    AbstractThe occurrence condition of geothermal resources in Jizhong depression is good for development, but the thermal genetic mechanism of thermal reservoir has been lack of systematic and theoretical research, which leads to large number of failure cases in the process of geothermal well location. In this paper, the thermal genetic mechanism of thermal reservoir in Jizhong depression is explored in the aspects of heat source, heat source channel, and thermophysical structure by means of core thermophysical property test, magnetotelluric sounding, and natural seismic P wave velocity imaging. According to the study, the heat of deep carbonate reservoir in Jizhong depression mainly comes from the deep mantle. Heat from the mantle enters deep thermal reservoir in the form of thermal conduction and thermal convection which flows through deep faults such as Niudong-Hexiwu fault. Cenozoic sandstone and mudstone caprock whose thermal conductivities are low is more than 1000 meters, which is favorable for heat storage. In comparison, the thermal conductivity of deep carbonate thermal reservoir is much higher than that of sandstone and mudstone. Therefore, differences in thermal conductivity and thermal convection from deep faults are the reasons why the heat reservoir temperature in the uplift area is higher than that in the subdepression area at the same depth

    Identification of mutations in porcine STAT5A that contributes to the transcription of CISH

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    Identification of causative genes or genetic variants associated with phenotype traits benefits the genetic improvement of animals. CISH plays a role in immunity and growth, however, the upstream transcriptional factors of porcine CISH and the genetic variations in these factors remain unclear. In this study, we firstly identified the minimal core promoter of porcine CISH and confirmed the existence of STATx binding sites. Overexpression and RT-qPCR demonstrated STAT5A increased CISH transcriptional activity (P < 0.01) and mRNA expression (P < 0.01), while GATA1 inhibited CISH transcriptional activity (P < 0.01) and the following mRNA expression (P < 0.05 or P < 0.01). Then, the putative functional genetic variations of porcine STAT5A were screened and a PCR-SSCP was established for genotype g.508A>C and g.566C>T. Population genetic analysis showed the A allele frequency of g.508A>C and C allele frequency of g.566C>T was 0.61 and 0.94 in Min pigs, respectively, while these two alleles were fixed in the Landrace population. Statistical analysis showed that Min piglets with CC genotype at g.566C>T or Hap1: AC had higher 28-day body weight, 35-day body weight, and ADG than TC or Hap3: CT animals (P < 0.05, P < 0.05). Further luciferase activity assay demonstrated that the activity of g.508A>C in the C allele was lower than the A allele (P < 0.05). Collectively, the present study demonstrated that STAT5A positively regulated porcine CISH transcription, and SNP g.566C>T in the STAT5A was associated with the Min piglet growth trait

    Hydroclimatic Variability and Predictability: A Survey of Recent Research

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    Recent research in large-scale hydroclimatic variability is surveyed, focusing on five topics: (i) variability in general, (ii) droughts, (iii) floods, (iv) land-atmosphere coupling, and (v) hydroclimatic prediction. Each surveyed topic is supplemented by illustrative examples of recent research, as presented at a 2016 symposium honoring the career of Professor Eric Wood. Taken together, the recent literature and the illustrative examples clearly show that current research into hydroclimatic variability is strong, vibrant, and multifaceted

    MicroRNA Expression Analysis in the Cellulosic Biofuel Crop Switchgrass (Panicum virgatum) under Abiotic Stress

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    Switchgrass has increasingly been recognized as a dedicated biofuel crop for its broad adaptation to marginal lands and high biomass. However, little is known about the basic biology and the regulatory mechanisms of gene expression in switchgrass, particularly under stress conditions. In this study, we investigated the effect of salt and drought stress on switchgrass germination, growth and the expression of small regulatory RNAs. The results indicate that salt stress had a gradual but significant negative effect on switchgrass growth and development. The germination rate was significantly decreased from 82% for control to 36% under 1% NaCl treatment. However, drought stress had little effect on the germination rate but had a significant effect on the growth of switchgrass under the severest salinity stress. Both salt and drought stresses altered the expression pattern of miRNAs in a dose-dependent manner. However, each miRNA responded to drought stress in a different pattern. Salt and drought stress changed the expression level of miRNAs mainly from 0.9-fold up-regulation to 0.7-fold down-regulation. miRNAs were less sensitive to drought treatment than salinity treatment, as evidenced by the narrow fold change in expression levels. Although the range of change in expression level of miRNAs was similar under salt and drought stress, no miRNAs displayed significant change in expression level under all tested salt conditions. Two miRNAs, miR156 and miR162, showed significantly change in expression level under high drought stress. This suggests that miR156 and miR162 may attribute to the adaption of switchgrass to drought stress and are good candidates for improving switchgrass as a biofuel crop by transgenic technology

    Flow field design and optimization based on, the mass transport polarization regulation in a flow-through type vanadium flow battery

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    Vanadium flow battery holds great promise for use in large scale energy storage applications. However, the power density is relatively low, leading to significant increase in the system cost. Apart from the kinetic and electronic conductivity improvement, the mass transport enhancement is also necessary to further increase the power density and reduce the system cost. To better understand the mass transport limitations, in the research, the space-varying and time-varying characteristic of the mass transport polarization is investigated based on the analysis of the flow velocity and reactant concentration in the bulk electrolyte by modeling. The result demonstrates that the varying characteristic of mass transport polarization is more obvious at high SoC or high current densities. To soften the adverse impact of the mass transport polarization, a new rectangular plug flow battery with a plug flow and short flow path is designed and optimized based on the mass transport polarization regulation (reducing the mass transport polarization and improving its uniformity of distribution). The regulation strategy of mass transport polarization is practical for the performance improvement in VFBs, especially for high power density VFBs. The findings in the research are also applicable for other flow batteries and instructive for practical use. (C) 2016 Elsevier B.V. All rights reserved

    Investigation on the performance evaluation method of flow batteries

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    Performance evaluation method is very important for the research on flow batteries. Charging discharging test is the most typical evaluation method for flow batteries. Recently, the polarization curves, together with the associated power density curves, which are commonly employed in fuel cells, have come into use for flow batteries' performance evaluation. Based on the investigation of performance evaluation method, it is confirmed charging discharging test is optimal for flow batteries' performance evaluation. A comparison of voltage losses (voltage efficiency, VE) can be clearly delivered from the polarization curves, which are quite practical for fuel cells' performance evaluation. While for flow batteries, apart from VE, coulombic efficiency (CE), energy efficiency (EE), utilization of electrolyte (UE) and capacity stability should be seriously considered during charging discharging process. However, CE and UE are inaccessible; accordingly. EE and capacity stability can't be detected from polarization curves. Therefore, the polarization curve is improper to serve as a performance evaluation method for flow batteries. On the premise of a proper CE, a rough performance evaluation for flow batteries can be achieved via the polarization curves. The peak power density is of limited significance in practical use due to the extremely low EE obtained at that point. (C) 2014 Elsevier B.V. All rights reserved

    Exercise Enhances Branched-Chain Amino Acid Catabolism and Decreases Cardiac Vulnerability to Myocardial Ischemic Injury

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    Long-term exercise-induced metabolic adaptations occupy a central position in exercise-afforded cardiac benefits. Emerging evidence suggests that branched-chain amino acid (BCAA) catabolic defect contributes to cardiac dysfunction in multiple cardiometabolic diseases. However, the role of BCAA catabolism in exercise-afforded cardiac benefits remains unknown. Here, we show that exercise improves BCAA catabolism and thus reduce cardiac vulnerability to myocardial ischemic injury. Exercise increased circulating BCAA levels in both humans (male adolescent athletes) and mice (following an 8-week swimming intervention). It increased the expression of mitochondrial localized 2C-type serine-threonine protein phosphatase (PP2Cm), a key enzyme in regulating BCAA catabolism, and decreased BCAA accumulation in mouse hearts, indicating an increase in BCAA catabolism. Pharmacological promotion of BCAA catabolism protected the mouse heart against myocardial infarction (MI) induced by permanent ligation of the left descending coronary artery. Although cardiac-specific PP2Cm knockout showed no significant effects on cardiac structural and functional adaptations to exercise, it blunted the cardioprotective effects of exercise against MI. Mechanistically, exercise alleviated BCAA accumulation and subsequently inactivated the mammalian target of rapamycin in MI hearts. These results showed that exercise elevated BCAA catabolism and protected the heart against myocardial ischemic injury, reinforcing the role of exercise in the promotion of cardiac health

    Hydroclimatic Variability and Predictability : A Survey of Recent Research

    No full text
    Recent research in large-scale hydroclimatic variability is surveyed, focusing on five topics: (i) variability in general, (ii) droughts, (iii) floods, (iv) land-atmosphere coupling, and (v) hydroclimatic prediction. Each surveyed topic is supplemented by illustrative examples of recent research, as presented at a 2016 symposium honoring the career of Professor Eric Wood. Taken together, the recent literature and the illustrative examples clearly show that current research into hydroclimatic variability is strong, vibrant, and multifaceted
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