The contribution of ultracompact dark matter minihalos to the isotropic radio background

The ultracompact minihalos could be formed during the earlier epoch of the universe. The dark matter annihilation within them is very strong due to the steep density profile, $\rho \sim r^{-2.25}$. The high energy electrons and positrons from the dark matter annihilation can inverse Compton scatter (ICS) with the background photons, such as CMB photons, to acquire higher energy. On the other hand, the synchrotron radiation can also be produced when they meet the magnetic field. In this paper, we study the signals from the UCMHs due to the dark matter annihilation for the radio, X-ray and $\gamma$-ray band. We found that for the radio emission the UCMHs can provide one kind of source for the radio excess observed by ARCADE 2. But the X-ray signals due to the ICS effect or the $\gamma$-ray signals mainly due to the prompt emission from dark matter would exceed the present observations, such as Fermi, COMPTEL and CHANDRA. We found that the strongest limits on the fraction of UCMHs come from the X-ray observations and the constraints from the radio data are the weakest.Comment: 6 pages, 8 figures, Comments Welcome! Some Refs. are added, some presentation have been corrected. The conclusions remain unchanged. One important reference has been corrected. Some presentations are changed and added according to the referee's comments. Accepted for publication in PR

XANES investigation of the local structure of Co nanoclusters embedded in Ag

Ion-implanted cobalt atoms into a silver matrix with a layer thickness of about 20 nm were studied by x-ray absorption near-edge spectroscopy (XANES) at the Co $K$ edge. Full multiple scattering ab initio calculations of Co XANES at the $K$ edge provide a phase fingerprint to distinguish the Co structure of samples prepared at different doses and annealing temperatures. The bcc Co phase is formed for the as-prepared sample with 6 at. % and the fcc Co phase is formed at the expense of the bcc phase for the sample with 12 at. % after annealing at $400\ifmmode^\circ\else\textdegree\fi{}\mathrm{C}.

XANES investigation of the local structure of Co nanoclusters embedded in Ag. Phys

Ion-implanted cobalt atoms into a silver matrix with a layer thickness of about 20 nm were studied by x-ray absorption near-edge spectroscopy ͑XANES͒ at the Co K edge. Full multiple scattering ab initio calculations of Co XANES at the K edge provide a phase fingerprint to distinguish the Co structure of samples prepared at different doses and annealing temperatures. The bcc Co phase is formed for the as-prepared sample with 6 at. % and the fcc Co phase is formed at the expense of the bcc phase for the sample with 12 at. % after annealing at 400°C

Single-cell multi-omics reveals dyssynchrony of the innate and adaptive immune system in progressive COVID-19.

Dysregulated immune responses against the SARS-CoV-2 virus are instrumental in severe COVID-19. However, the immune signatures associated with immunopathology are poorly understood. Here we use multi-omics single-cell analysis to probe the dynamic immune responses in hospitalized patients with stable or progressive course of COVID-19, explore V(D)J repertoires, and assess the cellular effects of tocilizumab. Coordinated profiling of gene expression and cell lineage protein markers shows that S100

DNA methylation on N6-adenine in mammalian embryonic stem cells

It has been widely accepted that 5-methylcytosine is the only form of DNA methylation in mammalian genomes. Here we identify N6-methyladenine as another form of DNA modification in mouse embryonic stem cells. Alkbh1 encodes a demethylase for N6-methyladenine. An increase of N6-methyladenine levels in Alkbh1-deficient cells leads to transcriptional silencing. N6-methyladenine deposition is inversely correlated with the evolutionary age of LINE-1 transposons; its deposition is strongly enriched at young (6 million years old) L1 elements. The deposition of N6-methyladenine correlates with epigenetic silencing of such LINE-1 transposons, together with their neighbouring enhancers and genes, thereby resisting the gene activation signals during embryonic stem cell differentiation. As young full-length LINE-1 transposons are strongly enriched on the X chromosome, genes located on the X chromosome are also silenced. Thus, N6-methyladenine developed a new role in epigenetic silencing in mammalian evolution distinct from its role in gene activation in other organisms. Our results demonstrate that N6-methyladenine constitutes a crucial component of the epigenetic regulation repertoire in mammalian genomes

Thermodynamic study on complex parts of the sphere and ellipsoid of a nuclear explosive device

Because the heat release of plutonium material, the composite structure is heated and the stress and strain of the composite structure will increase, which will affect the thermodynamic properties of the structure. The thermodynamic analysis of complex structures, which are composed of concentric structures of plutonium, beryllium, tungsten, explosives, and steel, was carried out. The results showed that when the structure is spherical, the temperature is higher than that of the ellipsoid structure. Stress of the elliptical structure is greater than the spherical structure. This study showed that the more flat the shell is, the greater the stress concentration point occurs at the long axis, and the maximum stress occurs at the beryllium layer. These conclusions provide theoretical support for the plutonium composite component testing