Chandra Observations of Six QSOs at z ≈\approx 3

We report the results of our Chandra observations of six QSOs at $z\sim 3$ from the Palomer Transit Grism Survey. Our primary goal is to investigate the possible systematic change of $\alpha_{ox}$ between $z>4$ and $z\sim 3$, between which a rapid rise of luminous QSO number density with cosmic time is observed. The summed spectrum showed a power-law spectrum with photon index of $\Gamma \approx 1.9$, which is similar to other unabsorbed AGNs. Combining our $z\sim 3$ QSOs with X-ray observations of QSOs at $z>4$ from literaure/archive, we find a correlation of $\alpha_{\rm ox}$ with optical luminosity. This is consistent with the fact that the luminosity function slope of the luminous end of the X-ray selected QSOs is steeper than that of optically-selected QSOs. We discuss an upper limit to the redshift dependence of $\alpha_{ox}$ using a Monte-Carlo simulation. Within the current statistical errors including the derived limits on the redshift dependence of $\alpha_{\rm ox}$, we found that the behaviors of the X-ray and optically-selected QSO number densities are consistent with each other.Comment: 13 Pages, 3 Figures, Astronomical Journal in press, An entry in Table 2 corrected--Log Lx for PC 1000+4751 from 44.0 (incorrect) to 45.0 (correct). A few minor errors correcte

The Chandra X-ray view of the power sources in Cepheus A

The central part of the massive star-forming region Cepheus A contains several radio sources which indicate multiple outflow phenomena, yet the driving sources of the individual outflows have not been identified. We present a high-resolution Chandra observation of this region that shows the presence of bright X-ray sources, consistent with active pre-main sequence stars, while the strong absorption hampers the detection of less luminous objects. A new source has been discovered located on the line connecting H_2 emission regions at the eastern and western parts of Cepheus A. This source could be the driving source of HH 168. We present a scenario relating the observed X-ray and radio emission.Comment: 7 pages, 6 figures, accepted for publication in A&

The evolution of the X-ray emission of HH 2 - Investigating heating and cooling processes

Young stellar objects often drive powerful bipolar outflows which evolve on time scales of a few years. An increasing number of these outflows has been detected in X-rays implying the existence of million degree plasma almost co-spatial with the lower temperature gas observed in the optical and near-IR. The details of the heating and cooling processes of the X-ray emitting part of these so-called Herbig-Haro objects are still ambiguous, e.g., whether the cooling is dominated by expansion, radiation or thermal conduction. We present a second epoch Chandra observation of the first X-ray detected Herbig-Haro object (HH 2) and derive the proper-motion of the X-ray emitting plasma and its cooling history. We argue that the most likely explanation for the constancy of the X-ray luminosity, the alignment with the optical emission and the proper-motion is that the cooling is dominated by radiative losses leading to cooling times exceeding a decade. We explain that a strong shock caused by fast material ramming into slower gas in front of it about ten years ago can explain the X-ray emission while being compatible with the available multi-wavelength data of HH 2.Comment: 5 pages with 4 figures; accepted for publication by Astronomy and Astrophysic

What Works Better? A Study of Classifying Requirements

Classifying requirements into functional requirements (FR) and non-functional ones (NFR) is an important task in requirements engineering. However, automated classification of requirements written in natural language is not straightforward, due to the variability of natural language and the absence of a controlled vocabulary. This paper investigates how automated classification of requirements into FR and NFR can be improved and how well several machine learning approaches work in this context. We contribute an approach for preprocessing requirements that standardizes and normalizes requirements before applying classification algorithms. Further, we report on how well several existing machine learning methods perform for automated classification of NFRs into sub-categories such as usability, availability, or performance. Our study is performed on 625 requirements provided by the OpenScience tera-PROMISE repository. We found that our preprocessing improved the performance of an existing classification method. We further found significant differences in the performance of approaches such as Latent Dirichlet Allocation, Biterm Topic Modeling, or Naive Bayes for the sub-classification of NFRs.Comment: 7 pages, the 25th IEEE International Conference on Requirements Engineering (RE'17

HST FUV C IV observations of the hot DG Tauri jet

Protostellar jets are tightly connected to the accretion process and regulate the angular momentum balance of accreting star-disk systems. The DG Tau jet is one of the best-studied protostellar jets and contains plasma with temperatures ranging over three orders of magnitude within the innermost 50 AU of the jet. We present new Hubble Space Telescope (HST) far ultraviolet (FUV) long-slit spectra spatially resolving the C IV emission (T~1e5 K) from the jet for the first time, and quasi-simultaneous HST observations of optical forbidden emission lines ([O I], [N II], [S II] and [O III]) and fluorescent H2 lines. The C IV emission peaks at 42 AU from the stellar position and has a FWHM of 52 AU along the jet. Its deprojected velocity of around 200 km/s decreases monotonically away from the driving source. In addition, we compare our HST data with the X-ray emission from the DG Tau jet. We investigate the requirements to explain the data by an initially hot jet compared to local heating. Both scenarios indicate a mass loss by the T~1e5 K jet of ~1e-9 Msun/year, i.e., between the values for the lower temperature jet (T~1e4 K) and the hotter X-ray emitting part (T>1e6 K). However, a simple initially hot wind requires a large launching region (~1 AU), and we therefore favor local heating.Comment: 5 pages, 2 figures, accepted by A&A letter

Safety of Catheter Embolization of Pulmonary Arteriovenous Malformations—Evaluation of Possible Cerebrovascular Embolism after Catheter Embolization of Pulmonary Arteriovenous Malformations in Patients with Hereditary Hemorrhagic Telangiectasia/Osler Disease by Pre- and Post-Interventional DWI

Background. This paper aimed to prospectively evaluate the safety of embolization therapy of pulmonary arteriovenous malformations (PAVMs) for the detection of cerebral infarctions by preand post-interventional MRI. Method One hundred and five patients (male/female = 44/61; mean age 48.6+/−15.8; range 5–86) with pre-diagnosed PAVMs on contrast-enhanced MRA underwent embolization therapy. The number of PAVMs treated in each patient ranged from 1–8 PAVMs. Depending on the size and localization of the feeding arteries, either Nester-Coils or Amplatzer vascular plugs were used for embolization therapy. cMRI was performed immediately before, and at the 4 h and 3-month post-embolization therapy. Detection of peri-interventional cerebral emboli was performed via T2w and DWI sequences using three different b-values, with calculation of ADC maps. Results Embolization did not show any post-/peri-interventional, newly developed ischemic lesions in the brain. Only one patient who underwent re-embolization and was previously treated with tungsten coils that corroded over time showed newly developed, small, diffuse emboli in the post-interventional DWI sequence. This patient already had several episodes of brain emboli before re-treatment due to the corroded coils, and during treatment, when passing the corroded coils, experienced additional small, clinically inconspicuous brain emboli. However, this complication was anticipated but accepted, since the vessel had to be occluded distally. Conclusion Catheter-based embolization of PAVMs is a safe method for treatment and does not result in clinically inconspicuous cerebral ischemia, which was not demonstrated previously

Outcomes and Tendon Integrity After Arthroscopic Treatment for Articular-Sided Partial-Thickness Tears of the Supraspinatus Tendon: Results at Minimum 2-Year Follow-Up

Background: The best surgical treatment option for symptomatic moderate- to high-grade articular-sided partial-thickness rotator cuff tears (PTRCTs) is still controversial. Purpose/Hypothesis: The purpose of this study was to evaluate patient-reported and clinical outcomes and tendon integrity after arthroscopic debridement or repair for PTRCTs at a minimum of 2 years postoperatively. We hypothesized that the overall outcomes would be positive, showing pain relief, good shoulder function, and high tendon integrity. Study Design: Cohort study; Level of evidence, 3. Methods: We evaluated 30 patients (16 men, 14 women; mean age, 51 years) who underwent arthroscopic treatment for symptomatic PTRCTs (Ellman grades 2 and 3). Debridement was performed in 15 patients, and arthroscopic tendon repair was performed in the remaining 15 patients. Patients completed the Constant score; American Shoulder and Elbow Surgeons (ASES) shoulder score; Western Ontario Rotator Cuff Index; Simple Shoulder Test; and visual analog scale (VAS) for pain, function, and satisfaction. In addition, patients were examined clinically (range of motion, impingement tests, rotator cuff tests, and tests for the long head of the biceps tendon), and morphologic assessment of rotator cuff integrity was performed using direct magnetic resonance arthrography and was classified according to Sugaya. Results: The mean follow-up period was 55 months. The patient-reported outcome measures showed high patient satisfaction, reduction in persistent pain, and good shoulder function. Linear regression analysis showed that the debridement group had significantly better results on the Constant (bias-corrected and accelerated [BCa] 95% CI, 4.20-26.30), ASES (BCa 95% CI, 5.24-39.26), and VAS (pain: BCa 95% CI, 0.13-3.62; function: BCa 95% CI, 1.04-4.84; satisfaction: BCa 95% CI, 0.14-6.28) scores than did the repair group. At follow-up, there was no significant difference between the groups in clinical testing results. Good supraspinatus tendon integrity was seen in most patients: Sugaya classification grade 1 in 13 patients, grade 2 in 11 patients, and grade 3 in 6 patients. Conclusion: Midterm results after arthroscopic debridement and repair for PTRCTs showed high patient satisfaction, good shoulder function, and high tendon integrity for both procedures. Patients who underwent arthroscopic debridement had higher Constant, ASES, and VAS scores compared with patients who underwent tendon repair

Diagnostic Performance of a Lower-dose Contrast-Enhanced 4D Dynamic MR Angiography of the Lower Extremities at 3 T Using Multisegmental Time-Resolved Maximum Intensity Projections

Background For peripheral artery disease (PAD), MR angiography (MRA) is a well-established diagnostic modality providing morphologic and dynamic information comparable to digital subtraction angiography (DSA). However, relatively large amounts of contrast agents are necessary to achieve this. Purpose To evaluate the diagnostic accuracy of time-resolved 4D MR-angiography with interleaved stochastic trajectories (TWIST-MRA) by using maximum intensity projections (MIPs) of dynamic images acquired with reduced doses of contrast agent. Study Type Retrospective. Population Forty adult PAD patients yielding 1088 artery segments. Field Strength/Sequence A 3.0 T, time-resolved 4D MR-angiography with TWIST-MRA and MIP of dynamic images. Assessment DSA was available in 14 patients (256 artery segments) and used as reference standard. Three-segmental MIP reconstructions of TWIST-images after administration of 3 mL of gadolinium-based contrast agent (Gadoteridol/Prohance®, 0.5 M) per anatomical level (pelvis, thighs, and lower legs) yielded 256 artery segments for correlation between MRA and DSA. Three independent observers rated image quality (scale: 1 [nondiagnostic] to 4 [excellent]) and the degree of venous overlay (scale: 0 [none] to 2 [significant]) for all segments. Diagnostic accuracy for the detection of >50% stenosis and artery occlusion was calculated for all observers. Statistical Tests Binary classification test (sensitivity, specificity, positive/negative predictive values, diagnostic accuracy). Intraclass correlation coefficients (ICCs), logistic regression analysis with comparison of areas under the receiver-operating-characteristics (ROC) curves (AUCs) with the DeLong method. Bland–Altman-comparison. Results High diagnostic performance was achieved for the detection of >50% stenosis (sensitivity 92.9% [84.3–99.9% (95%-CI)] and specificity 98.5% [95.7–99.8% (95%-CI)]) and artery occlusion (sensitivity 93.1% [77.2–99.2% (95%-CI)] and specificity 99.1% [96.9–99.9% (95%-CI)]). Inter-reader agreement was excellent with ICC values ranging from 0.95 to 1.0 for >50% artery stenosis and occlusion. Image quality was good to excellent for both readers (3.41 ± 0.72, 3.33 ± 0.65, and 3.38 ± 0.61 [mean ± SD]) with good correlation between observer ratings (ICC 0.71–0.81). No significant venous overlay was observed (0.06 ± 0.24, 0.23 ± 0.43 and 0.11 ± 0.45 [mean ± SD]). Data Conclusion MIPs of dynamic TWIST-MRA offer a promising diagnostic alternative necessitating only reduced amounts (50%) of gadolinium-based contrast agents for the entire runoff vasculature. Evidence Level 3 Technical Efficacy Stage