Disagreement Resolution in Family Travel Decision-Making—The Role of Adult Children

Adult children traveling with their parents is gaining increasing popularity. As adult children and parents grown up in different social environment, they have formed dissimilar beliefs and core values, which may cause decision-making disagreements when traveling together. However, there has been little research to understand how adult children handle the disagreement with their parents in family trip. Based on this, the current study aims to resolve this question. Moreover, given adult children usually show great filial piety to their parents, and have developed more power in family decision-making. The role of filial piety and decision-making power in adult children’s disagreement management deserve thorough investigations. Specifically, this study examines: (1) How adult children resolve the disagreement in family vacation decision-making; (2) How the filial duty and decision-making power of adult children influences their disagreement resolution. A mixed-methods approach including interviews and scenario-based experiments will be adopted to solve these two problems

Regulation of arginine methyltransferase 3 by a Wolbachia-induced microRNA in Aedes aegypti and its effect on Wolbachia and dengue virus replication

The gram-negative endosymbiotic bacteria, Wolbachia, have been found to colonize a wide range of invertebrates, including over 40% of insect species. Best known for host reproductive manipulations, some strains of Wolbachia have been shown to reduce the host life span by about 50% and inhibit replication and transmission of dengue virus (DENV) in the mosquito vector, Aedes aegypti. The molecular mechanisms underlying these effects still are not well understood. Our previous studies showed that Wolbachia uses host microRNAs (miRNAs) to manipulate host gene expression for its efficient maintenance and limiting replication of DENV in Ae. aegypti. Protein arginine methyltransferases are structurally and functionally conserved proteins from yeast to human. In mammals, it has been reported that protein arginine methyltransferases such as PRMT1, 5 and 6 could regulate replication of different viruses. Ae. aegypti contains eight members of protein arginine methyltransferases (AaArgM1-8). Here, we show that the wMelPop strain of Wolbachia introduced into Ae. aegypti significantly induces the expression of AaArgM3. Interestingly, we found that Wolbachia uses aae-miR-2940, which is highly upregulated in Wolbachia-infected mosquitoes, to upregulate the expression of AaArgM3. Silencing of AaArgM3 in a mosquito cell line led to the inhibition of Wolbachia replication, but had no effect on the replication of DENV. These results provide further evidence that Wolbachia uses the host miRNAs to manipulate host gene expression and facilitate colonization in Ae. aegypti mosquito

Ionothermal Synthesis, Crystal Structure, and Magnetic Study of Co2PO4OH Isostructural with Caminite

A new framework cobalt(II) hydroxyl phosphate, Co2PO4OH, was prepared by ionothermal synthesis using 1-butyl-4-methyl-pyridinium hexafluorophosphate as the ionic liquid. As the formation of Co2PO4F competes in the synthesis, the synthesis conditions have to be judiciously chosen to obtain well-crystallized, single phase Co2PO4OH. Single-crystal X-ray diffraction analyses reveal Co2PO4OH crystallizes with space group I41/amd (a = b = 5.2713(7) Å, c = 12.907(3) Å, V = 358.63(10) Å3, and Z = 4). Astonishingly, it does not crystallize isotypically with Co2PO4F but rather isotypically with the hydroxyl minerals caminite Mg1.33[SO4(OH)0.66(H2O)0.33] and lipscombite Fe2–yPO4(OH) (0 ≤ y ≤ 2/3). Phosphate tetrahedra groups interconnect four rod-packed face-sharing ∞1{CoO6/2} octahedra chains to form a three-dimensional framework structure. The compound Co2PO4OH was further characterized by powder X-ray diffraction, Fourier transform–infrared, and ultraviolet–visible spectroscopy, confirming the discussed structure. The magnetic measurement reveals that Co2PO4OH undergoes a magnetic transition and presents at low temperatures a canted antiferromagnetic spin order in the ground state

Value Co-Creation and Co-Destruction Through Adult Child–Parent Interactions During Family Vacations: Scale Development and Validation

Although numerous benefits of family vacations have been recognized, the value of family interactions during tourism activities remains under-explored in the literature. Through a series of dual-perspective studies using both qualitative and quantitative approaches, this research developed and validated two multidimensional datasets to measure value co-creation and co-destruction from the perspectives of adult children and their parents on family vacations. The results demonstrate that interactions between adult children and their parents may lead to co-created and co-destructed value, and that children and parents perceive interactive value structures differently. The research also identified two antecedents (family role clarity and prior knowledge) and one consequence (overall experience evaluation) of value co-creation and co-destruction. By developing and validating an effective dual scale for assessing value co-creation and co-destruction through adult child-parent interactions during family vacations, this study advances research on family travel and provides practical evidence that help improve the family travel experience

Preparation and properties of biodegradable spent tea leaf powder/poly(propylene carbonate) composite films

Abstract: The aim of the present work is to develop novel biobased lightweight material with improved tensile and thermal properties. Spent tea leaf powder (STLP) is used as a filler to improve the tensile and thermal properties of polypropylene carbonate (PPC). Tea is an important material of hotels and household and spent tea leaf forms a conjugal solid waste. Composite films are obtained by solution casting method. These films are characterized by Optical microscopy, scanning electron microscopy, Fourier transforms infrared spectroscopy, thermogravimetric analysis and tensile testing to examine the effect of filler content on the properties of the composites. The results have shown that composite films are having increased tensile strength due to enhanced interfacial adhesion between the filler and the matrix. In addition, the composite films have also exhibited higher thermal degradation temperatures compared to pure polypropylene carbonate. The morphology results indicate that there is a good interface interaction between STLP and PPC. Results of the study reveal STLP to be a promising green filler for polymer plastics

Soluble CD40 ligand-activated human peripheral B cells as surrogated antigen presenting cells: A preliminary approach for anti-HBV immunotherapy

<p>Abstract</p> <p>Background</p> <p>We aimed to clarify whether soluble CD40 ligand (sCD40L) activated B cells may be loaded with HBcAg18-27 peptide and served as antigen-producing cells (APCs) to induce HBV-specific cytolytic T lymphocytes (CTLs).</p> <p>Results</p> <p>Human B cells could be cultured in the presence of sCD40L up to 54 days, and the proportion of B cells in the S phase increased from 0% to 8.34% in the culture. The expression of CD80, CD86, major histocompatibility complex (MHC) classes I and II molecules on the sCD40L-activated B cell was significantly increased after long-time culture. Cytometry and fluorescence microscopy showed that more than 98% sCD40L-activated B cells were loaded by the HBcAg peptide. Furthermore, the peptide-pulsed activated B cells could induce HBcAg18-27 specific CTLs.</p> <p>Conclusions</p> <p>Our results demonstrate that sCD40L-activated B cells may function as APCs and induce HBV-specific CTLs.</p

Simulating soil salinity dynamics, cotton yield and evapotranspiration under drip irrigation by ensemble machine learning

We thank the China Scholarship Council (CSC) for providing a scholarship (202206710073) to Zewei Jiang. This work was supported by the Fundamental Research Funds for the Central Universities (B220203009), the Postgraduate Research & Practice Program of Jiangsu Province (KYCX22_0669), the Water Conservancy Science and Technology Project of Jiangxi Province (201921ZDKT06, 202124ZDKT09), the National Natural Science Foundation of China (51879076), the Fundamental Research Funds for the Central Universities (B210204016), Science & Technology Specific Projects in Agricultural High-tech Industrial Demonstration Area of the Yellow River Delta, Grant No: 2022SZX01.Peer reviewedPublisher PD

Hypoventilation in the PACU is associated with hypoventilation in the surgical ward: Post-hoc analysis of a randomized clinical trial

Objective: To evaluate the association between early postoperative hypoventilation in the last hour of the post -anesthesia care unit (PACU) stay and hypoventilation during the rest of the first 48 postoperative hours in the surgical ward. Design: Sub-analysis of a clinical trial. Setting: PACU and surgical wards of a single medical center. Patients: Adults having abdominal surgery under general anesthesia. Interventions: Monitoring with a respiratory volume monitor from admission to PACU until the earlier of 48 h after surgery or discharge. Measurements: The exposure was having at least one low minute-ventilation (MV) event during the last hour of PACU stay, defined as MV lower than 40% the predicted value lasting at least 1 min. The primary outcome was low MV events lasting at least 2 min during the rest of the first 48 postoperative hours, while in the surgical ward. The secondary outcome was the rate of low MV events per monitored hour. Main results: Data of 292 patients were analyzed, of which 20 (6.8%) patients had a low MV event in PACU. Low MV events in the surgical ward were found in 81 (28%) patients. All patients who had low MV events in PACU had events again in the ward, while 61/272 (22%) had an event in the ward but not in PACU. The incidence rate of low MV events per hour was 24 (95% CI: 13, 46) among patients having an event in the PACU, and 2 (1, 4) among those who did not. Conclusions: In adults recovering from abdominal surgery, events of hypoventilation during the first post-operative hour are associated with similar events during the rest of the first 48 postoperative hours, with positive predictive value approaching 100%. Sixty-one patients had ward hypoventilation that was not preceded by hypoventilation in PACU