698 research outputs found
Study on China's Regional Carbon Emission Factors: The case of Chongqing City
AbstractLow-carbon development has become a hot issue concerned by the whole world. Governments respectively introduced the country's low-carbon strategy and action. China has put forward a series of obligatory targets and has issued a provincial area “twelfth five-year” carbon intensity reduction target. How to coordinate the contradiction between economic growth and environmental constraints, and formulating corresponding low-carbon development path and the supporting measures, has become one of the problems to be solved. Considering the regional resource endowment, stage of economic development, energy structure, industrial structure, technical development level and other factors, this article constructs the model of regional carbon emission factors, the paper takes Chongqing of China as an example. The research results show that: The major contribution of elements, in turn, is the improvement of technology energy efficiency, the optimization of energy structure, and the adjustment of industrial structure. Based on this, this paper puts forward the corresponding low-carbon development policies according to the results of analysis, from the aspects such as energy structure, industrial structure, and technological progress and so on
Metal-to-semiconductor transition in squashed armchair carbon nanotubes
We investigate electronic transport properties of the squashed armchair
carbon nanotubes, using tight-binding molecular dynamics and Green's function
method. We demonstrate a metal-to-semiconductor transistion while squashing the
nanotubes and a general mechanism for such transistion. It is the distinction
of the two sublattices in the nanotube that opens an energy gap near the Fermi
energy. We show that the transition has to be achieved by a combined effect of
breaking of mirror symmetry and bond formation between the flattened faces in
the squashed nanotubes.Comment: 4 papges, 4 figures, to appear in Phys. Rev. Let
Benzyl 2-ethylhexyl sulfoxide
The molecule of the title compound, C15H24OS, shows S conformations for the S atom and the asymmetric C atom of the isooctyl group. The long axes of the molecules are directed along the c axis. In the crystal structure, the molecules are linked by weak intermolecular bifurcated C—H⋯O hydrogen bonds
Nebulette knockout mice have normal cardiac function, but show Z-line widening and up-regulation of cardiac stress markers
Aims: Nebulette is a 109 kDa modular protein localized in the sarcomeric Z-line of the heart. In vitro studies have suggested a role of nebulette in stabilizing the thin filament, and missense mutations in the nebulette gene were recently shown to be causative for dilated cardiomyopathy and endocardial fibroelastosis in human and mice. However, the role of nebulette in vivo has remained elusive. To provide insights into the function of nebulette in vivo, we generated and studied nebulette-deficient (nebl-/-) mice. Methods and results: Nebl-/- mice were generated by replacement of exon 1 by Cre under the control of the endogenous nebulette promoter, allowing for lineage analysis using the ROSA26 Cre reporter strain. This revealed specific expression of nebulette in the heart, consistent with in situ hybridization results. Nebl-/- mice exhibited normal cardiac function both under basal conditions and in response to transaortic constriction as assessed by echocardiography and haemodynamic analyses. Furthermore, histological, IF, and western blot analysis showed no cardiac abnormalities in nebl-/- mice up to 8 months of age. In contrast, transmission electron microscopy showed Z-line widening starting from 5 months of age, suggesting that nebulette is important for the integrity of the Z-line. Furthermore, up-regulation of cardiac stress responsive genes suggests the presence of chronic cardiac stress in nebl-/- mice. Conclusion: Nebulette is dispensable for normal cardiac function, although Z-line widening and up-regulation of cardiac stress markers were found in nebl-/- heart. These results suggest that the nebulette disease causing mutations have dominant gain-of-function effects
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The Muscle Ankyrin Repeat Proteins CARP, Ankrd2, and DARP Are Not Essential for Normal Cardiac Development and Function at Basal Conditions and in Response to Pressure Overload
Ankrd1/CARP, Ankrd2/Arpp, and Ankrd23/DARP belong to a family of stress inducible ankyrin repeat proteins expressed in striated muscle (MARPs). The MARPs are homologous in structure and localized in the nucleus where they negatively regulate gene expression as well as in the sarcomeric I-band, where they are thought to be involved in mechanosensing. Together with their strong induction during cardiac disease and the identification of causative Ankrd1 gene mutations in cardiomyopathy patients, this suggests their important roles in cardiac development, function, and disease. To determine the functional role of MARPs in vivo, we studied knockout (KO) mice of each of the three family members. Single KO mice were viable and had no apparent cardiac phenotype. We therefore hypothesized that the three highly homologous MARP proteins may have redundant functions in the heart and studied double and triple MARP KO mice. Unexpectedly, MARP triple KO mice were viable and had normal cardiac function both at basal levels and in response to mechanical pressure overload induced by transverse aortic constriction as assessed by echocardiography and hemodynamic studies. Thus, CARP, Ankrd2, and DARP are not essential for normal cardiac development and function at basal conditions and in response to mechanical pressure overload
Nitrogen defects and ferromagnetism of Cr-doped AlN diluted magnetic semiconductor from first principles
High Curie temperature of 900 K has been reported in Cr-doped AlN diluted
magnetic semiconductors prepared by various methods, which is exciting for
spintronic applications. It is believed that N defects play important roles in
achieving the high temperature ferromagnetism in good samples. Motivated by
these experimental advances, we use a full-potential density-functional-theory
method and supercell approach to investigate N defects and their effects on
ferromagnetism of (Al,Cr)N with N vacancies (V_N). Calculated results are in
agreement with experimental observations and facts of real Cr-doped AlN samples
and their synthesis. Our first-principles results are useful to elucidating the
mechanism for the ferromagnetism and exploring high-performance Cr-doped AlN
diluted magnetic semiconductors.Comment: 8 pages with figures include
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