325 research outputs found
Comment on "Deuterium--tritium fusion reactors without external fusion breeding" by Eliezer et al
Inclusion of inverse Compton effects in the calculation of
deuterium-deuterium burn under the extreme conditions considered by Eliezer et
al. [Phys. Lett. A 243 (1998) 298] are shown to decrease the maximum burn
temperature from about 300 keV to only 100--150 keV. This decrease is such that
tritium breeding by the DD --> T + p reaction is not sufficient to replace the
small amount of tritium that is initially added to the deuterium plasma in
order to trigger ignition at less than 10 keV.Comment: 6 pages, 1 tabl
Generalized second-order partial derivatives of 1/r
The generalized second-order partial derivatives of 1/r, where r is the
radial distance in 3D, are obtained using a result of the potential theory of
classical analysis. Some non-spherical regularization alternatives to the
standard spherical-regularization expression for the derivatives are derived.
The utility of a spheroidal-regularization expression is illustrated on an
example from classical electrodynamics.Comment: 12 pages; as accepted for publication by European Journal of Physic
Matter effects in the D0-D0bar system
We discuss the impact of matter effects in the D0-D0bar system. We show that
such effects could, in principle, be measured, but that they cannot be used to
probe the mass difference x_D or the lifetime difference y_D. This occurs
because the mixing effects and the matter effects decouple at short times. We
also comment briefly on the B systems.Comment: 6 pages, RevTe
Cornelius Lanczos's derivation of the usual action integral of classical electrodynamics
The usual action integral of classical electrodynamics is derived starting
from Lanczos's electrodynamics -- a pure field theory in which charged
particles are identified with singularities of the homogeneous Maxwell's
equations interpreted as a generalization of the Cauchy-Riemann regularity
conditions from complex to biquaternion functions of four complex variables. It
is shown that contrary to the usual theory based on the inhomogeneous Maxwell's
equations, in which charged particles are identified with the sources, there is
no divergence in the self-interaction so that the mass is finite, and that the
only approximation made in the derivation are the usual conditions required for
the internal consistency of classical electrodynamics. Moreover, it is found
that the radius of the boundary surface enclosing a singularity interpreted as
an electron is on the same order as that of the hypothetical "bag" confining
the quarks in a hadron, so that Lanczos's electrodynamics is engaging the
reconsideration of many fundamental concepts related to the nature of
elementary particles.Comment: 16 pages. Final version to be published in "Foundations of Physics
Diketopyrrolopyrrole-fullerene C60 architectures as highly efficient heavy atom-free photosensitizers: Synthesis, photophysical properties and photodynamic activity
Chromophore-fullerene C60 hybrids possess interesting properties that enable them to act as heavy atom-free photosensitizers and reactive oxygen species (ROS) producers. Here, two new diketopyrrolopyrrole-C60 conjugates were efficiently synthesized and characterized. The conjugates show broadband absorption in the visible spectral region, in which diketopyrrolopyrrole dyes act as light-harvesting antenna with very high capacity to populate excited triplet states. Furthermore, the ability of diketopyrrolopyrrole-C60 systems to generate singlet molecular oxygen was explored for the first time in solvents of different polarities. The experimental results show that these architectures exhibit very high production rates of this ROS. In addition, a preliminary study on Staphylococcus aureus cell suspensions indicates that both conjugates exhibit phototoxicity after irradiation with green LED light. Thus, the data obtained provide evidence that these diketopyrrolopyrrole-C60 architectures act as potential heavy atom-free photosensitizers in photodynamic inactivation of microorganisms and other singlet oxygen-mediated applications.Fil: Agazzi, Maximiliano Luis. Universidad Nacional de Río Cuarto. Instituto para el Desarrollo Agroindustrial y de la Salud. - Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto para el Desarrollo Agroindustrial y de la Salud; ArgentinaFil: Almodovar, Vitor A. S.. Universidade de Aveiro; PortugalFil: Gsponer, Natalia Soledad. Universidad Nacional de Río Cuarto. Instituto para el Desarrollo Agroindustrial y de la Salud. - Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto para el Desarrollo Agroindustrial y de la Salud; ArgentinaFil: Bertolotti, Sonia Graciela. Universidad Nacional de Río Cuarto. Instituto para el Desarrollo Agroindustrial y de la Salud. - Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto para el Desarrollo Agroindustrial y de la Salud; ArgentinaFil: Tomé, Augusto C.. Universidade de Aveiro; PortugalFil: Durantini, Edgardo Néstor. Universidad Nacional de Río Cuarto. Instituto para el Desarrollo Agroindustrial y de la Salud. - Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto para el Desarrollo Agroindustrial y de la Salud; Argentin
Rsp5/Nedd4 is the main ubiquitin ligase that targets cytosolic misfolded proteins following heat stress
The heat-shock response is a complex cellular program that induces major changes in protein translation, folding and degradation to alleviate toxicity caused by protein misfolding. Although heat shock has been widely used to study proteostasis, it remained unclear how misfolded proteins are targeted for proteolysis in these conditions. We found that Rsp5 and its mammalian homologue Nedd4 are important E3 ligases responsible for the increased ubiquitylation induced by heat stress. We determined that Rsp5 ubiquitylates mainly cytosolic misfolded proteins upon heat shock for proteasome degradation. We found that ubiquitylation of heat-induced substrates requires the Hsp40 co-chaperone Ydj1 that is further associated with Rsp5 upon heat shock. In addition, ubiquitylation is also promoted by PY Rsp5-binding motifs found primarily in the structured regions of stress-induced substrates, which can act as heat-induced degrons. Our results support a bipartite recognition mechanism combining direct and chaperone-dependent ubiquitylation of misfolded cytosolic proteins by Rsp5
Maxwell Fields and Shear-Free Null Geodesic Congruences
We study and report on the class of vacuum Maxwell fields in Minkowski space
that possess a non-degenerate, diverging, principle null vector field (null
eigenvector field of the Maxwell tensor) that is tangent to a shear-free null
geodesics congruence. These congruences can be either surface forming (the
tangent vectors proportional to gradients) or not, i.e., the twisting
congruences. In the non-twisting case, the associated Maxwell fields are
precisely the Lienard-Wiechert fields, i.e., those Maxwell fields arising from
an electric monopole moving on an arbitrary worldline. The null geodesic
congruence is given by the generators of the light-cones with apex on the
world-line. The twisting case is much richer, more interesting and far more
complicated. In a twisting subcase, where our main interests lie, it can be
given the following strange interpretation. If we allow the real Minkowski
space to be complexified so that the real Minkowski coordinates x^a take
complex values, i.e., x^a => z^a=x^a+iy^a with complex metric g=eta_abdz^adz^b,
the real vacuum Maxwell equations can be extended into the complex and
rewritten as curlW =iWdot, divW with W =E+iB. This subcase of Maxwell fields
can then be extended into the complex so as to have as source, a complex
analytic world-line, i.e., to now become complex Lienard-Wiechart fields. When
viewed as real fields on the real Minkowski space, z^a=x^a, they possess a real
principle null vector that is shear-free but twisting and diverging. The twist
is a measure of how far the complex world-line is from the real 'slice'. Most
Maxwell fields in this subcase are asymptotically flat with a time-varying set
of electric and magnetic moments, all depending on the complex displacements
and the complex velocities.Comment: 3
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