Negotiating Value: Comparing Human and Animal Fracture Care in Industrial Societies

At the beginning of the twentieth-century, human and veterinary surgeons faced the challenge of a medical marketplace transformed by technology. The socio-economic value ascribed to their patients – people and domestic animals – was changing, reflecting the increasing mechanisation of industry and the decreasing dependence of society upon non-human animals for labour. In human medicine, concern for the economic consequences of fractures “pathologised” any significant level of post-therapeutic disability, a productivist perspective contrary to the traditional corpus of medical values. In contrast, veterinarians adapted to the mechanisation of horse-power by shifting their primary professional interest to companion animals; a type of veterinary patient generally valued for the unique emotional attachment of the owner, and not the productive capacity of the animal. The economic rationalisation of human fracture care and the “sentimental” transformation of veterinary orthopaedic expertise indicates how these specialists utilised increasingly convergent rhetorical arguments to justify the application of innovative fracture care technologies to their humans and animal patients. Keywords: Fracture care, Industrialisation, Veterinary History, Human/animal relation

PHANGS-ALMA data processing and pipeline

Instrumentatio

Evaluating the Effects of SARS-CoV-2 Spike Mutation D614G on Transmissibility and Pathogenicity

Global dispersal and increasing frequency of the SARS-CoV-2 spike protein variant D614G are suggestive of a selective advantage but may also be due to a random founder effect. We investigate the hypothesis for positive selection of spike D614G in the United Kingdom using more than 25,000 whole genome SARS-CoV-2 sequences. Despite the availability of a large dataset, well represented by both spike 614 variants, not all approaches showed a conclusive signal of positive selection. Population genetic analysis indicates that 614G increases in frequency relative to 614D in a manner consistent with a selective advantage. We do not find any indication that patients infected with the spike 614G variant have higher COVID-19 mortality or clinical severity, but 614G is associated with higher viral load and younger age of patients. Significant differences in growth and size of 614G phylogenetic clusters indicate a need for continued study of this variant

Shock Excited Molecules in NGC 1266 : ULIRG Conditions at the Center of a Bulge-dominated Galaxy

We investigate the far infrared (IR) spectrum of NGC 1266, a S0 galaxy that contains a massive reservoir of highly excited molecular gas. Using the Herschel Fourier Transform Spectrometer, we detect the 12CO ladder up to J = (13-12), [C I] and [N II] lines, and also strong water lines more characteristic of UltraLuminous IR Galaxies (ULIRGs). The 12CO line emission is modeled with a combination of a low-velocity C-shock and a photodissociation region. Shocks are required to produce the H2O and most of the high-J CO emission. Despite having an IR luminosity 30 times less than a typical ULIRG, the spectral characteristics and physical conditions of the interstellar medium of NGC 1266 closely resemble those of ULIRGs, which often harbor strong shocks and large-scale outflowsPeer reviewe