A Look at Public Health

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Enhancement of nonclassical properties of two qubits via deformed operators

We explore the dynamics of two atoms interacting with a cavity field via deformed operators. Properties of the asymptotic regularization of entanglement measures proving, for example, purity cost, regularized fidelity and accuracy of information transfer are analyzed. We show that the robustness of a bipartite system having a finite number of quantum states vanishes at finite photon numbers, for arbitrary interactions between its constituents and with cavity field. Finally it is shown that the stability of the purity and the fidelity is improved in the absence of the deformation parameters

PDXNet portal: patient-derived Xenograft model, data, workflow and tool discovery.

We created the PDX Network (PDXNet) portal (https://portal.pdxnetwork.org/) to centralize access to the National Cancer Institute-funded PDXNet consortium resources, to facilitate collaboration among researchers and to make these data easily available for research. The portal includes sections for resources, analysis results, metrics for PDXNet activities, data processing protocols and training materials for processing PDX data. Currently, the portal contains PDXNet model information and data resources from 334 new models across 33 cancer types. Tissue samples of these models were deposited in the NCI\u27s Patient-Derived Model Repository (PDMR) for public access. These models have 2134 associated sequencing files from 873 samples across 308 patients, which are hosted on the Cancer Genomics Cloud powered by Seven Bridges and the NCI Cancer Data Service for long-term storage and access with dbGaP permissions. The portal includes results from freely available, robust, validated and standardized analysis workflows on PDXNet sequencing files and PDMR data (3857 samples from 629 patients across 85 disease types). The PDXNet portal is continuously updated with new data and is of significant utility to the cancer research community as it provides a centralized location for PDXNet resources, which support multi-agent treatment studies, determination of sensitivity and resistance mechanisms, and preclinical trials

The importance of patient-specific preoperative factors: An analysis of The Society of Thoracic Surgeons Congenital Heart Surgery Database

BACKGROUND: The most common fonns of risk adjustment for pediatric and congenital heart surgery used today are based mainly on the estimated risk of mortality of the primary procedure of the operation. The goals of this analysis were to assess the association of patient-specific preoperative factors with mortality and to determine which of these preoperative factors to include in future pediatric and congenital cardiac surgical risk models. METHODS: All index cardiac operations in The Society of Thoracic Surgeons Congenital Heart Surgery Database (STS-CHSD) during 2010 through 2012 were eligible for inclusion. Patients weighing less than 2.5 kg undergoing patent ductus arteriosus closure were excluded. Centers with more than 10% missing data and patients with missing data for discharge mortality or other key variables were excluded. Rates of discharge mortality for patients with or without specific preoperative factors were assessed across age groups and were compared using Fisher's exact test. RESULTS: In all, 25,476 operations were included (overall discharge mortality 3.7%, n = 943). The prevalence of common preoperative factors and their associations with discharge mortality were determined. Associations of the following preoperative factors with discharge mortality were all highly significant (p < 0.0001) for neonates, infants, and children: mechanical circulatory support, renal dysfunction, shock, and mechanical ventilation. CONCLUSIONS: Current STS-CHSD risk adjustment is based on estimated risk of mortality of the primary procedure of the operation as well as age, weight, and prematurity. The inclusion of additional patient-specific preoperative factors in risk models for pediatric and congenital cardiac surgery could lead to increased precision in predicting risk of operative mortality and comparison of observed to expected outcomes

A storm safari in subtropical South America: Proyecto RELAMPAGO

This article provides an overview of the experimental design, execution, education and public outreach, data collection, and initial scientific results from the Remote Sensing of Electrification, Lightning, and Mesoscale/Microscale Processes with Adaptive Ground Observations (RELAMPAGO) field campaign. RELAMPAGO was a major field campaign conducted in the Córdoba and Mendoza provinces in Argentina and western Rio Grande do Sul State in Brazil in 2018-19 that involved more than 200 scientists and students from the United States, Argentina, and Brazil. This campaign was motivated by the physical processes and societal impacts of deep convection that frequently initiates in this region, often along the complex terrain of the Sierras de Córdoba and Andes, and often grows rapidly upscale into dangerous storms that impact society. Observed storms during the experiment produced copious hail, intense flash flooding, extreme lightning flash rates, and other unusual lightning phenomena, but few tornadoes. The five distinct scientific foci of RELAMPAGO-convection initiation, severe weather, upscale growth, hydrometeorology, and lightning and electrification-are described, as are the deployment strategies to observe physical processes relevant to these foci. The campaign's international cooperation, forecasting efforts, and mission planning strategies enabled a successful data collection effort. In addition, the legacy of RELAMPAGO in South America, including extensive multinational education, public outreach, and social media data gathering associated with the campaign, is summarized.Fil: Nesbitt, Stephen William. University of Illinois. Urbana - Champaign; Estados UnidosFil: Salio, Paola Veronica. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Centro de Investigaciones del Mar y la Atmósfera; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Centro de Investigaciones del Mar y la Atmósfera. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Centro de Investigaciones del Mar y la Atmósfera; Argentina. Instituto Franco-Argentino sobre Estudios del Clima y sus Impactos; ArgentinaFil: Avila, Eldo Edgardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Física Enrique Gaviola. Universidad Nacional de Córdoba. Instituto de Física Enrique Gaviola; ArgentinaFil: Bitzer, Phillip. The University Of Alabama In Huntsville; Estados UnidosFil: Carey, Lawrence. The University Of Alabama In Huntsville; Estados UnidosFil: Chandrasekar, V.. State University of Colorado - Fort Collins; Estados UnidosFil: Deierling, Wiebke. State University of Colorado at Boulder; Estados UnidosFil: Dominguez, Francina. University of Illinois. Urbana - Champaign; Estados UnidosFil: Dillon, María Eugenia. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Ministerio de Defensa. Secretaria de Planeamiento. Servicio Meteorológico Nacional; ArgentinaFil: Garcia Rodriguez, Carlos Marcelo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Córdoba; ArgentinaFil: Gochis, David. National Center for Atmospheric Research; Estados UnidosFil: Goodman, Steven. Thunderbolt Global Analytics; Estados UnidosFil: Hence, Deanna A.. University of Illinois. Urbana - Champaign; Estados UnidosFil: Kosiba, Karen A.. Center For Severe Weather Research; Estados UnidosFil: Kumjian, Matthew R.. State University of Pennsylvania; Estados UnidosFil: Lang, Timothy. National Aeronautics and Space Administration; Estados UnidosFil: Luna, Lorena Medina. National Center for Atmospheric Research; Estados UnidosFil: Marquis, James. Pacific Northwest National Laboratory; Estados UnidosFil: Marshall, Robert. State University of Colorado at Boulder; Estados UnidosFil: McMurdie, Lynn A.. University of Washington; Estados UnidosFil: de Lima Nascimento, Ernani. Universidade Federal de Santa Maria; BrasilFil: Rasmussen, Kristen L.. State University of Colorado - Fort Collins; Estados UnidosFil: Roberts, Rita. National Center for Atmospheric Research; Estados UnidosFil: Rowe, Angela K.. University of Wisconsin; Estados UnidosFil: Ruiz, Juan Jose. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Centro de Investigaciones del Mar y la Atmósfera; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Centro de Investigaciones del Mar y la Atmósfera. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Centro de Investigaciones del Mar y la Atmósfera; Argentina. Instituto Franco-Argentino sobre Estudios del Clima y sus Impactos; ArgentinaFil: São Sabbas, Eliah F.M.T.. Centro de Previsao de Tempo e Estudos Climáticos. Instituto Nacional de Pesquisas Espaciais; BrasilFil: Saulo, Andrea Celeste. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Centro de Investigaciones del Mar y la Atmósfera. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Centro de Investigaciones del Mar y la Atmósfera; Argentina. Ministerio de Defensa. Secretaria de Planeamiento. Servicio Meteorológico Nacional; ArgentinaFil: Schumacher, Russ S.. State University of Colorado - Fort Collins; Estados UnidosFil: Garcia Skabar, Yanina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Ministerio de Defensa. Secretaria de Planeamiento. Servicio Meteorológico Nacional; ArgentinaFil: Machado, Luiz Augusto Toledo. Centro de Previsao de Tempo e Estudos Climáticos. Instituto Nacional de Pesquisas Espaciais; BrasilFil: Trapp, Robert J.. University of Illinois. Urbana - Champaign; Estados UnidosFil: Varble, Adam. Pacific Northwest National Laboratory; Estados UnidosFil: Wilson, James. National Center for Atmospheric Research; Estados UnidosFil: Wurman, Joshua. Center For Severe Weather Research; Estados UnidosFil: Zipser, Edward J.. University of Utah; Estados UnidosFil: Auvieux Arias, Gabriel Ivan. State University of Colorado - Fort Collins; Estados UnidosFil: Bechis, Hernán. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Centro de Investigaciones del Mar y la Atmósfera. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Centro de Investigaciones del Mar y la Atmósfera; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Centro de Investigaciones del Mar y la Atmósfera; Argentina. Instituto Franco-Argentino sobre Estudios del Clima y sus Impactos; ArgentinaFil: Grover, Maxwell A.. University of Illinois. Urbana - Champaign; Estados Unido