2-aminoaethanesulfonic acid compounds possess protective property in reperfusion-induced heart jnjury

The study aim was to explore pharmacological effects of 2-aminoaethansulfonic acid compounds in reperfusion-induced heart injury. The study was performed on rats and dogs of both sexes, isolated rats’ hearts. Two compounds of 2-aminoethanesulfonic acid, magnesium-containing (LBK-527) and phenylacetamide-containing (LKhT-317) were investigate

Quantum Law: The Beginning

Objective: to formulate the bases for quantum law as the law of the future, based on the study of quantum phenomena and features of quantum technologies determining the risks and challenges associated with the emergence of these technologies, as well as the analysis of legal regulation of quantum technologies in the Russian Federation and abroad.Methods: to carry out this research, the authors applied a complex of general scientific methods of systemic analysis and specific methods of engineering and legal sciences. The use of comparative-legal method allowed revealing the main directions of developing legal regulation of quantum technologies in the Russian and foreign law orders based on the analysis of their international and national regulation. The method of legal modeling allowed forming a concept of quantum law, revealing the main vectors of its development and the complex of its ethical-legal principles.Results: the features and properties of quantum technologies were revealed which can change the development of law with the advent of these technologies; the main risks and challenges were identified which are associated with the development of quantum technologies; the features of quantum technologies regulation in some foreign countries were specified; the trends of developing the quantum technologies regulation in the Russian Federation were identified; the conceptual bases of quantum law were formulated, as well as the vectors of its development.Scientific novelty: for the first time in the legal science, a complex analysis of the current national (both Russian and foreign) regulation of quantum technologies was carried out, based on which an attempt was made to substantiate the need to form quantum law and to outline the main vectors of its development.Practical significance: the research results lay the foundation for forming the concept of quantum law; in this regard, the authors’ conclusions and proposals for improving the current regulation of quantum technologies can be used in law-making and law enforcement in this sphere, and may lay the bases for further research in the sphere of quantum technologies

Magnetospheric convection from Cluster EDI measurements compared with the ground-based ionospheric convection model IZMEM

Cluster/EDI electron drift observations above the Northern and Southern polar cap areas for more than seven and a half years (2001–2008) have been used to derive a statistical model of the high-latitude electric potential distribution for summer conditions. Based on potential pattern for different orientations of the interplanetary magnetic field (IMF) in the GSM y-z-plane, basic convection pattern (BCP) were derived, that represent the main characteristics of the electric potential distribution in dependence on the IMF. The BCPs comprise the IMF-independent potential distribution as well as patterns, which describe the dependence on positive and negative IMF<I>B<sub>z</sub></I> and IMF<I>B<sub>y</sub></I> variations. The full set of BCPs allows to describe the spatial and temporal variation of the high-latitude electric potential (ionospheric convection) for any solar wind IMF condition near the Earth's magnetopause within reasonable ranges. The comparison of the Cluster/EDI model with the IZMEM ionospheric convection model, which was derived from ground-based magnetometer observations, shows a good agreement of the basic patterns and its variation with the IMF. According to the statistical models, there is a two-cell antisunward convection within the polar cap for northward IMF<I>B<sub>z</sub></I>+≤2 nT, while for increasing northward IMF<I>B<sub>z</sub></I>+ there appears a region of sunward convection within the high-latitude daytime sector, which assumes the form of two additional cells with sunward convection between them for IMF<I>B<sub>z</sub></I>+≈4–5 nT. This results in a four-cell convection pattern of the high-latitude convection. In dependence of the ±IMF<I>B<sub>y</sub></I> contribution during sufficiently strong northward IMF<I>B<sub>z</sub></I> conditions, a transformation to three-cell convection patterns takes place

Production of ²³⁵Np, ²³⁶Pu and ²³⁷Pu via nuclear reactions on ^235,236,238U and ²³⁷Np targets

A summary of methods for cyclotron production of 235Np (396.1d), 236Pu (2.858y) and 237Pu (45.2d) via nuclear reactions with protons and 3He-ions on 235,236,238U and 237Np targets in wide energy ranges is given. Methods for the chemical separation and purification of these nuclides from the irradiated uranium and neptunium targets are described. Cross sections, yields and radionuclidic purities of 235Np, 236Pu and 237Pu are presented and compared with literature data on the nuclear reactions leading to these radionuclides. The nuclear reactions with the so far highest known yields of 235Np, 236Pu and 237Pu are determined: 236U(p, 2n)235Np, 237Np(p, 2n + pnβ-)236Pu and 237Np(p, n) 237Pu, respectively. The highest radionuclidic purity of 235Np, 236Pu and 237Pu tracers can be reached with the 236U(p, 2n)235Np, 236U(p, nβ -)236Pu and 237Np(3He, t) 237Pu reactions, respectively. In addition new cross sections and yield data of the 236U(3He, p3n)235Np reaction in the energy range 42.4-60 MeV are given.</p

МОРФОФУНКЦІОНАЛЬНІ ОСОБЛИВОСТІ ПЛАЦЕНТИ ПРИ АНТЕНАТАЛЬНІЙ ЗАГИБЕЛІ ПЛОДА

Частота плацентарної недостатності у вагітних з вірусною або бактеріальною інфекцією досягає 50-60%. У разі антенатальної загибелі плоду послід стає одним з основних джерел діагностики інфекції та визначення причин його смерті. Мета дослідження. Вивчення особливостей морфологічної будови плаценти при антенатальній загибелі плода. Матеріал і методи дослідження. Нами було проведено аналіз морфологічних характеристик і мікробіологічних висновків 30 послідів жінок з антенатальною загибеллю плода (основна група) і 25 послідів жінок, які народили живих дітей (контрольна група). Результати дослідження. У жінок основної групи товщина плацент була на 15,1%, обсяг – на 22,5%, а площа – на 19,6% більше, ніж у осіб контрольної групи (р 0,05), інфекційно-запальні зміни при мікроскопічному дослідженні посліду виявлені в 26 (86,7%) випадках у жінок основної та у 4 (16%) осіб контрольної груп(р <0,05). Висновки. Запальні зміни в плаценті можуть стати причиною формування плацентарної недостатності і приводити до антенатальної загибелі плоду

Regional Aspects of Nosocomial Infection As a Medical and Social Problem

Prevention of nosocomial infection (NI) is an important medical and socioeconomic problem. And though certain organizational and practical measures are implemented in Russia every year to reduce NIs, the problem is still relevant from medical and social points of view. The risk of infection are both for patients and medical workers. In Russia, the minimum economic damage caused by NIs is 2.5–5 billion rubles annually. According to the Office of the Federal Service for Supervision of Consumer Rights Protection and Human Welfare in the Republic of Mordovia, the total incidence of NI in the region is at a low level. The incidence rate was 0.01 per 1000 patients in hospitals. The dynamics of the last five years demonstrates a decrease in hospital-acquired infections. In the dynamics of the last five years, incidence rates of purulent-septic infections of newborns and postpartum women, postoperative purulent-septic complications and post-injection complications had an unstable downward trend. Thus, purulent-septic infections of newborns and postpartum women and postoperative infections are dominated in the structure of nosocomial infections. Analysis of dynamics of morbidity in recent years in the Republic of Mordovia suggests that the measures taken to prevent NI are quite effective and are manifested with consistently low rates

DASHBOARD INDICATORS OF THE PUBLIC SERVICE

It formulated the need for new guidelines that take into account the possibility of formalization and analysis of processes in the discharge of public functions by public servants. Dashboard monitoring of the execution of state functions to civil servants is one of the topics to be discussed today. However, for the possibility of monitoring the key task is to identify the key evaluation indicators. Among the dashboard indicators need to be identified such as the performance, team and leadership assessment effective organization of the processes of execution of the state functions and competences of civil servants. To analyze the data from different angles and positions, is the best data exploration tool Data Discovery

DASHBOARD INDICATORS OF THE PUBLIC SERVICE

It formulated the need for new guidelines that take into account the possibility of formalization and analysis of processes in the discharge of public functions by public servants. Dashboard monitoring of the execution of state functions to civil servants is one of the topics to be discussed today. However, for the possibility of monitoring the key task is to identify the key evaluation indicators. Among the dashboard indicators need to be identified such as the performance, team and leadership assessment effective organization of the processes of execution of the state functions and competences of civil servants. To analyze the data from different angles and positions, is the best data exploration tool Data Discovery

Metal-containing taurine compounds protect rat’s brain in reperfusion-induced injury

The study aim was to explore a neuroprotective action of magnesium (LKhT-317) and zinc (LKhT-318) taurine salts on experimental models of reperfusion brain damage in rats and cell cultur