6,859 research outputs found
Dilute Birman--Wenzl--Murakami Algebra and models
A ``dilute'' generalisation of the Birman--Wenzl--Murakami algebra is
considered. It can be ``Baxterised'' to a solution of the Yang--Baxter algebra.
The vertex models are examples of corresponding solvable
lattice models and can be regarded as the dilute version of the
vertex models.Comment: 11 page
Ein neuartiges Antriebs- und Verstellsystem zur sicheren Plazierung von Biopsienadeln im Mammagewebe
Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG geförderten) Allianz- bzw. Nationallizenz frei zugänglich.This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence (funded by the DFG, German Research Foundation) respectively.In der Diagnostik des Mammakarzinoms werden die Mammographie und Sonographie vor allem durch die hochauflösende Magnetresonanztomographic unterstützt [2|. Ist für die weitere Diagnostik oder Therapieplanung eine Mammabiopsie indiziert, sollte sie durch das bildgebende Verfahren gestützt werden, das die Läsion am besten darstellt [1]. Durch die technische Weiterentwicklung der o.g. bildgebenden Verfahren gelingt es jetzt immer besser auch Tumoren von wenigen Millimetern im Durchmesser darzustellen [3]. Leider hat sich die Treffsicherheit der Biopsiesysteme nicht parallel dazu entwickelt, so dass eine geschlossene MRgeführte Biopsie erst ab einer Tumorgröße von 10mm durchgeführt werden sollte [4]. Gefördert durch die Deutsche Krebshilfe wurde am Institut für Mikrotechnik und Medizintechnik der Technischen Universität Berlin in enger Zusammenarbeit mit Kliniken der Charite Berlin ein neuartiges Biopsiesystem für histologische Untersuchungen von Mammatumoren im Frühstadium (< 5 mm) entwickelt, das eine vollautomatische Mammabiopsie direkt im Isozentrum eines Kernspintomographen ermöglicht, Die Steuerung und Überwachung der automatisierten Biopsie erfolgt durch einen Steuercomputer, der über Lichtwellenleiter mit dem Biopsiesystem verbunden ist. Für dieses Biopsiesystem wird ein Antriebs- und Verstellsystem vorgestellt, das eine stufenlose Einstellung der Eindringtiefe der Biopsienadcl in das Marnmagewebe und den Vorschub des Schussapparates auf einen halben Millimeter genau ermöglicht
Anomaly Cancelation in Field Theory and F-theory on a Circle
We study the manifestation of local gauge anomalies of four- and
six-dimensional field theories in the lower-dimensional Kaluza-Klein theory
obtained after circle compactification. We identify a convenient set of
transformations acting on the whole tower of massless and massive states and
investigate their action on the low-energy effective theories in the Coulomb
branch. The maps employ higher-dimensional large gauge transformations and
precisely yield the anomaly cancelation conditions when acting on the one-loop
induced Chern-Simons terms in the three- and five-dimensional effective theory.
The arising symmetries are argued to play a key role in the study of the
M-theory to F-theory limit on Calabi-Yau manifolds. For example, using the fact
that all fully resolved F-theory geometries inducing multiple Abelian gauge
groups or non-Abelian groups admit a certain set of symmetries, we are able to
generally show the cancelation of pure Abelian or pure non-Abelian anomalies in
these models.Comment: 48 pages, 2 figures; v2: typos corrected, comments on circle fluxes
adde
Non-universality of artificial frustrated spin systems
Magnetic frustration effects in artificial kagome arrays of nanomagnets with
out-of-plane magnetization are investigated using Magnetic Force Microscopy and
Monte Carlo simulations. Experimental and theoretical results are compared to
those found for the artificial kagome spin ice, in which the nanomagnets have
in-plane magnetization. In contrast with what has been recently reported, we
demonstrate that long range (i.e. beyond nearest-neighbors) dipolar
interactions between the nanomagnets cannot be neglected when describing the
magnetic configurations observed after demagnetizing the arrays using a field
protocol. As a consequence, there are clear limits to any universality in the
behavior of these two artificial frustrated spin systems. We provide arguments
to explain why these two systems show striking similarities at first sight in
the development of pairwise spin correlations.Comment: 7 pages, 6 figure
Diastolic function in hypertrophic cardiomyopathy: effects of propranolol and verapamil on diastolic stiffness
In patients with hypertrophic cardiomyopathy (HCM), impaired left ventricular (LV) relaxation and diastolic filling have been reported. Therefore, we determined LV diastolic stiffness in nine patients with HCM before and 10 to 15 min after 0·15 mg/kg propranolol i.v. (group 1) and in six patients with HCM before and 10 to 15 min after 0·1 mg/kg verapamil i.v. (group 2). Simultaneous LV cineangiography and high-fidelity pressure measurements were performed in group 1 and simultaneous M-mode echocardiography and high-fidelity pressure measurements in group 2. Passive LV chamber stiffness was determined in group 1 from the diastolic pressure-volume data using an exponential three-parameter model: P =αeβV + C, where P = pressure, α = intercept, β = constant of chamber stiffness, V = volume and C = baseline pressure. Passive LV myocardial stiffness was estimated in group 2 from the diastolic stress-strain data using a viscoelastic model. ο = α′ (eβ′ε - 1) + ηέ, where ο = meridional wall stress, α = intercept, β′ = constant of myocardial stiffness, ε = midwall strain, η = constant of myocardial viscosity and έ = strain rate. LV relaxation was assessed from the time constant of LV pressure decay (T) by plotting LV pressure versus negative dP/dt. LV diastolic filling was evaluated from peak and mean LV filling rate in group I and from peak and mean midwall lengthening rate in group 2. LV chamber and myocardial stiffness, respectively, remained unchanged before and after administration of propranolol (β=0·054 and 0·047) and verapamil (β = 14·8 and 12·6); however, the time constant of LV pressure decay T increased significantly in group I from 45 to 66 ms (P<0·05) and decreased significantly in group 2 from 53 to 43 ms (P<0·05). Parallel to the changes in LV isovolumic relaxation, mean LV diastolic filling rate decreased significantly in group 1 from 257 to 196 ml m−2 s−1 (P<0·025) and mean LV midwall lengthening rate increased significantly in group 2 from 2·37 to 4·31 cm/sec (P<0<05). It is concluded that LV diastolic stiffness remains unchanged in patients with HCM after propranolol and verapamil. LV relaxation and mean diastolic filling, however, are impaired in patients with HCM following propranolol but are improved after verapamil. Thus, the beneficial effect of verapamil on diastolic mechanics is related to improved relaxation and diastolic filling rather than to changes in LV diastolic stiffnes
Energy levels and their correlations in quasicrystals
Quasicrystals can be considered, from the point of view of their electronic
properties, as being intermediate between metals and insulators. For example,
experiments show that quasicrystalline alloys such as AlCuFe or AlPdMn have
conductivities far smaller than those of the metals that these alloys are
composed from. Wave functions in a quasicrystal are typically intermediate in
character between the extended states of a crystal and the exponentially
localized states in the insulating phase, and this is also reflected in the
energy spectrum and the density of states. In the theoretical studies we
consider in this review, the quasicrystals are described by a pure hopping
tight binding model on simple tilings. We focus on spectral properties, which
we compare with those of other complex systems, in particular, the Anderson
model of a disordered metal.Comment: 15 pages including 19 figures. Review article, submitted to Phil. Ma
The Impact of Vitamin E and Other Fat-Soluble Vitamins on Alzheimer´s Disease
Alzheimer’s disease (AD) is the most common cause of dementia in the elderly population, currently affecting 46 million people worldwide. Histopathologically, the disease is characterized by the occurrence of extracellular amyloid plaques composed of aggregated amyloid-β (Aβ) peptides and intracellular neurofibrillary tangles containing the microtubule-associated protein tau. Aβ peptides are derived from the sequential processing of the amyloid precursor protein (APP) by enzymes called secretases, which are strongly influenced by the lipid environment. Several vitamins have been reported to be reduced in the plasma/serum of AD-affected individuals indicating they have an impact on AD pathogenesis. In this review we focus on vitamin E and the other lipophilic vitamins A, D, and K, and summarize the current knowledge about their status in AD patients, their impact on cognitive functions and AD risk, as well as their influence on the molecular mechanisms of AD. The vitamins might affect the generation and clearance of Aβ both by direct effects and indirectly by altering the cellular lipid homeostasis. Additionally, vitamins A, D, E, and K are reported to influence further mechanisms discussed to be involved in AD pathogenesis, e.g., Aβ-aggregation, Aβ-induced neurotoxicity, oxidative stress, and inflammatory processes, as summarized in this article
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