Tuberculose vertebral (doença de Pott) associada a abscesso de psoas: relato de dois casos e revisão da literatura Spinal tuberculosis (Pott's disease) associated to psoas abscess: report of two cases and a literature review

A tuberculose é uma das principais doenças infecciosas de acometimento mundial com 3,9 milhões de casos notificados no mundo, em 2002. A forma esquelética pode corresponder a 3% do número total de casos, sendo 50% devido à tuberculose vertebral. O abscesso de psoas é uma entidade clínica rara com aproximadamente 12 casos relatados por ano na literatura médica e tem no Mycobacterium tuberculosis, um dos seus agentes etiológicos. O objetivo deste trabalho é relatar dois casos de tuberculose vertebral associada a abscesso de psoas atendidos em nosso serviço, bem como uma revisão da literatura.<br>Tuberculosis is one of the most important infectious disease worldwide, with 3,9 million reported cases in the world in 2002. The skeletal form is responsible for 3% of the total number of cases, with 50% of these due to spinal tuberculosis. The psoas abscess is a rare clinical entity with approximately 12 cases per year described in the medical literature and has in the Mycobacterium tuberculosis , one of its etiologic agents. The objective of this work is to report two cases of spinal tuberculosis associated with psoas abscess attended at our service, as well as a review of the literature

The search for the neutron electric dipole moment at the Paul Scherrer Institute

The measurement of the neutron electric dipole moment (nEDM) constrains the contribution of CP-violating terms within both the Standard Model and its extensions. The experiment uses ultracold neutrons (UCN) stored in vacuum at room temperature. This technique provided the last (and best) limit by the RAL/Sussex/ILL collaboration in 2006: dn < 2:9 × 10⁻²⁶ e cm (90% C.L.). We aim to improve the experimental sensitivity by a factor of 5 within 2-3 years, using an upgrade of the same apparatus. We will take advantage of the increased ultracold neutron density at the Paul Scherrer Institute (PSI) and of a new concept including both, external magnetometers and a cohabiting magnetometer. In parallel, a next generation apparatus with two UCN storage chambers and an elaborate magnetic field control is being designed aiming to achieve another order of magnitude increase in sensitivity, allowing us to put a limit as tight as dn < 5 × 10⁻²⁸ e cm (95% C.L.), if not establishing a finite value

The emotional feeling as a combination of two qualia: A neurophilosophical-based emotion theory

It is argued that the emotional feeling comprises the following two emotional qualia. (1) A nucleus feeling or primary emotional quale, which is the phenomenological counterpart of the end product of appraisal by the central nervous system. (2) The experience of being urged to emotion-related reflection or secondary emotional quale, which is the phenomenological counterpart of the brain’s decision to inhibit pre-programmed emotional behaviour, and to initiate emotion-related reflections. Different brain modules regulate these two qualia, and thus each can be experienced independently of the other. The primary emotional quale is related to activation of the amygdala, it is emotion specific, and neutral with respect to affect. The secondary emotional quale is related to activation of the orbito-prefrontal cortex (O-PFC), and includes affective aspects. It is argued that emotional behaviour is regulated by the following three neural mechanisms, two of which two are directly related to the two qualia. (1) An evolutionary ancient system (amygdala-system), which comprises the amygdalae and subcortical nuclei, and which activates pre-programmed emotional behaviour. (2) An evolutionary recent system (PFC-system), comprising the prefrontal cortex, which inhibits pre-programmed emotional behaviour, activates emotional reflection, generates and evaluates behavioural alternatives. In contrast to the preprogrammed behaviour, the behavioural alternatives are more likely to serve longterm goals. (3) A default mechanism, which gives rise to default (i.e., ‘‘just do something’’) behaviour. The first two systems are mutually competitive, while the third mechanism takes over if either the competition between the first two mechanisms, or the decision process of the PFC-system, takes too long. This default mechanism involves the function of the medial-prefrontal cortex (M-PFC)