Flueric-controller pneumatic stepping motor system

Nutating stepping motor consists of an output rotating gear and a nutating gear. A flueric logic circuit controls the nutating motor. The complete system constitutes a reliable, open loop actuator system with inherently high output stiffness, reasonable slewing speeds and small step size

Long-term material compatibility testing system

System includes procedure for hermetically sealing solid materials and fluids in glass ampoule and use of temperature-controlled facility containing sample holder, which permits sample containers to be retrieved safely and conveniently. Solid material and fluid are sealed within chemically-clean glass ampoule according to highly detailed procedure

A new molecular diagnostic tool for surveying and monitoring Triops cancriformis populations

© 2017 Sellers et al. The tadpole shrimp, Triops cancriformis, is a freshwater crustacean listed as endangered in the UK and Europe living in ephemeral pools. Populations are threatened by habitat destruction due to land development for agriculture and increased urbanisation. Despite this, there is a lack of efficient methods for discovering and monitoring populations. Established macroinvertebrate monitoring methods, such as net sampling, are unsuitable given the organism's life history, that include long lived diapausing eggs, benthic habits and ephemerally active populations. Conventional hatching methods, such as sediment incubation, are both time consuming and potentially confounded by bet-hedging hatching strategies of diapausing eggs. Here we develop a new molecular diagnostic method to detect viable egg banks of T. cancriformis, and compare its performance to two conventional monitoring methods involving diapausing egg hatching. We apply this method to a collection of pond sediments from the Wildfowl & Wetlands Trust Caerlaverock National Nature Reserve, which holds one of the two remaining British populations of T. cancriformis. DNA barcoding of isolated eggs, using newly designed species-specific primers for a large region of mtDNA, was used to estimate egg viability. These estimates were compared to those obtained by the conventional methods of sediment and isolation hatching. Our method outperformed the conventional methods, revealing six ponds holding viable T. cancriformis diapausing egg banks in Caerlaverock. Additionally, designed species-specific primers for a short region of mtDNA identified degraded, inviable eggs and were used to ascertain the levels of recent mortality within an egg bank. Together with efficient sugar flotation techniques to extract eggs from sediment samples, our molecular method proved to be a faster and more powerful alternative for assessing the viability and condition of T. cancriformis diapausing egg banks

Quantum Fluctuations in Dipolar Bose Gases

We investigate the influence of quantum fluctuations upon dipolar Bose gases by means of the Bogoliubov-de Gennes theory. Thereby, we make use of the local density approximation to evaluate the dipolar exchange interaction between the condensate and the excited particles. This allows to obtain the Bogoliubov spectrum analytically in the limit of large particle numbers. After discussing the condensate depletion and the ground-state energy correction, we derive quantum corrected equations of motion for harmonically trapped dipolar Bose gases by using superfluid hydrodynamics. These equations are subsequently applied to analyze the equilibrium configuration, the low-lying oscillation frequencies, and the time-of-flight dynamics. We find that both atomic magnetic and molecular electric dipolar systems offer promising scenarios for detecting beyond mean-field effects.Comment: Published in PR

An algorithm for determining program feasibility of a multi-mode PAM commutator telemetry system Technical report no. 10

Algorithm formulation for evaluation of strapping arrangement programs for PAM multimode commutation system of Saturn telemetry syste

Numerical calculations of a high brilliance synchrotron source and on issues with characterizing strong radiation damping effects in non-linear Thomson/Compton backscattering experiments

A number of theoretical calculations have studied the effect of radiation reaction forces on radiation distributions in strong field counter-propagating electron beam-laser interactions, but could these effects - including quantum corrections - be observed in interactions with realistic bunches and focusing fields, as is hoped in a number of soon to be proposed experiments? We present numerical calculations of the angularly resolved radiation spectrum from an electron bunch with parameters similar to those produced in laser wakefield acceleration experiments, interacting with an intense, ultrashort laser pulse. For our parameters, the effects of radiation damping on the angular distribution and energy distribution of \emph{photons} is not easily discernible for a "realistic" moderate emittance electron beam. However, experiments using such a counter-propagating beam-laser geometry should be able to measure such effects using current laser systems through measurement of the \emph{electron beam} properties. In addition, the brilliance of this source is very high, with peak spectral brilliance exceeding $10^{29}$ photons$\,$s$^{-1}$mm$^{-2}$mrad$^{-2}(0.1$% bandwidth$)^{-1}$ with approximately 2% efficiency and with a peak energy of 10 MeV.Comment: 11 figures, 11 page

Statistical quality control applied to a telemetry system acceptance prodedure Technical report no. 13

Statistical quality control applied to telemetry system acceptance procedur

The reduced cost of providing a nationally recognised service for familial hypercholesterolaemia

OBJECTIVE: Familial hypercholesterolaemia (FH) affects 1 in 500 people in the UK population and is associated with premature morbidity and mortality from coronary heart disease. In 2008, National Institute for Health and Care Excellence (NICE) recommended genetic testing of potential FH index cases and cascade testing of their relatives. Commissioners have been slow to respond although there is strong evidence of cost and clinical effectiveness. Our study quantifies the recent reduced cost of providing a FH service using generic atorvastatin and compares NICE costing estimates with three suggested alternative models of care (a specialist-led service, a dual model service where general practitioners (GPs) can access specialist advice, and a GP-led service).METHODS: Revision of existing 3?year costing template provided by NICE for FH services, and prediction of costs for running a programme over 10?years. Costs were modelled for the first population-based FH service in England which covers Southampton, Hampshire, Isle of Wight and Portsmouth (SHIP). Population 1.95 million.RESULTS: With expiry of the Lipitor (Pfizer atorvastatin) patent the cost of providing a 10-year FH service in SHIP reduces by 42.5% (£4.88 million on patent vs £2.80 million off patent). Further cost reductions are possible as a result of the reduced cost of DNA testing, more management in general practice, and lower referral rates to specialists. For instance a dual-care model with GP management of patients supported by specialist advice when required, costs £1.89 million.CONCLUSIONS: The three alternative models of care are now <50% of the cost of the original estimates undertaken by NICE

Scalable Peer-to-Peer Streaming for Live Entertainment Content

We present a system for streaming live entertainment content over the Internet originating from a single source to a scalable number of consumers without resorting to centralized or provider-provisioned resources. The system creates a peer-to-peer overlay network, which attempts to optimize use of existing capacity to ensure quality of service, delivering low startup delay and lag in playout of the live content. There are three main aspects of our solution: first, a swarming mechanism that constructs an overlay topology for minimizing propagation delays from the source to end consumers; second, a distributed overlay anycast system that uses a location-based search algorithm for peers to quickly find the closest peers in a given stream; and finally, a novel incentive mechanism that encourages peers to donate capacity even when the user is not actively consuming content