44 research outputs found
Statistical Properties of Interacting Bose Gases in Quasi-2D Harmonic Traps
The analytical probability distribution of the quasi-2D (and purely 2D) ideal
and interacting Bose gas are investigated by using a canonical ensemble
approach. Using the analytical probability distribution of the condensate, the
statistical properties such as the mean occupation number and particle number
fluctuations of the condensate are calculated. Researches show that there is a
continuous crossover of the statistical properties from a quasi-2D to a purely
2D ideal or interacting gases. Different from the case of a 3D Bose gas, the
interaction between atoms changes in a deep way the nature of the particle
number fluctuations.Comment: RevTex, 10pages, 4 figures, E-mail: [email protected]
Gut-central nervous system axis is a target for nutritional therapies
Historically, in the 1950s, the chemist Linus Pauling established a relationship between decreased longevity and obesity. At this time, with the advent of studies involving the mechanisms that modulate appetite control, some researchers observed that the hypothalamus is the "appetite centre" and that peripheral tissues have important roles in the modulation of gut inflammatory processes and levels of hormones that control food intake. Likewise, the advances of physiological and molecular mechanisms for patients with obesity, type 2 diabetes mellitus, inflammatory bowel diseases, bariatric surgery and anorexia-associated diseases has been greatly appreciated by nutritionists. Therefore, this review highlights the relationship between the gut-central nervous system axis and targets for nutritional therapies
From gut dysbiosis to altered brain function and mental illness: mechanisms and pathways
The human body hosts an enormous abundance and diversity of microbes, which perform a range of essential and beneficial functions. Our appreciation of the importance of these microbial communities to many aspects of human physiology has grown dramatically in recent years. We know, for example, that animals raised in a germ-free environment exhibit substantially altered immune and metabolic function, while the disruption of commensal microbiota in humans is associated with the development of a growing number of diseases. Evidence is now emerging that, through interactions with the gut-brain axis, the bidirectional communication system between the central nervous system and the gastrointestinal tract, the gut microbiome can also influence neural development, cognition and behaviour, with recent evidence that changes in behaviour alter gut microbiota composition, while modifications of the microbiome can induce depressive-like behaviours. Although an association between enteropathy and certain psychiatric conditions has long been recognized, it now appears that gut microbes represent direct mediators of psychopathology. Here, we examine roles of gut microbiome in shaping brain development and neurological function, and the mechanisms by which it can contribute to mental illness. Further, we discuss how the insight provided by this new and exciting field of research can inform care and provide a basis for the design of novel, microbiota-targeted, therapies.GB Rogers, DJ Keating, RL Young, M-L Wong, J Licinio, and S Wesseling
Gut and Breast Milk Microbiota and Their Role in the Development of the Immune Function
The gastrointestinal immune system consists of both innate and adaptive immunity. The microbiota plays an important role in gastrointestinal immune function. In newborns, the maternal gut microbiota may either come across into the amniotic fluid or secrete factors that enter the amniotic fluid and affect the development of oral tol- erance in utero. Adequate colonization must occur in the immediate postpartum period for the appropriate mucosal immune response since it is apparent that later attempts at colonization do not have the same impact. Human milk, being also a direct source of microbes, represents one of the main factors that play a critical role in influencing infant’s microbiota composition