Telecommuting and social engagement

This entry describes the author\u27s experience during quarantine as the student, husband, and father of two.https://dc.ewu.edu/covid/1027/thumbnail.jp

Meiofauna community structure and function in the northern Gulf of Mexico deep sea

Meiofauna, a highly diverse group of small metazoans, are ubiquitous in deep-sea soft sediments and exhibit high abundance and biomass compared to larger-sized invertebrates (e.g., macrofauna). The northern Gulf of Mexico deep sea is characterized by topographical contrasts, with the flat topography of the Florida slope followed by the precipitous depth increase of the Florida escarpment; the complex Texas/Louisiana slope with numerous basins and knolls; and numerous canyon features such as the Mississippi Trough and DeSoto Canyon. Meiofauna community structure (abundance, biomass, and diversity) and function (respiration and feeding rates) were analyzed along with environmental variables in a hypothesis-based univariate and multivariate design, to more fully understand the distribution meiofauna, regional species pools, processes structuring communities, and how they respond to topographic, geochemical and physical forcing in the northern Gulf of Mexico. Meiofauna abundance is significantly related to water depth, but also exhibits significant longitudinal differences resulting from proximity to Mississippi River outflow. Multivariate comparisons of meiofauna abundance and diversity with environmental variables reveals a strong Mississippi River influence. River outflow alters local sediment characteristics, and interacts with loop current eddies and dynamic slope topography to increase POM flux in the northeastern region, thus creating areas of enhanced meiofauna abundance, biomass, and respiration, but lower functional harpacticoid copepod diversity. However, most stations have unique harpacticoid species compositions, suggesting high regional (2700 species) and global (105 - 106 species) diversity by extrapolation. Although highest harpacticoid diversity, in terms of expected number of species (rarefraction), is found at approximately 1200 meters, average taxonomic and average phylogenetic diversity continue to increase with depth, indicating greater morphological or functional diversity. High within versus between station variability suggests an interaction between small and region-scale processes maintaining high diversity. Allometric estimates indicate that meiofauna require 7% of their biomass per day to meet their metabolic energy budget, and account for 10-25% of whole sediment community respiration, indicating their importance in global biogeochemical cycles.Marine Scienc

A new approach to wind energy: Opportunities and challenges

Despite common characterizations of modern wind energy technology as mature, there remains a persistent disconnect between the vast global wind energy resource—which is 20 times greater than total global power consumption—and the limited penetration of existing wind energy technologies as a means for electricity generation worldwide. We describe an approach to wind energy harvesting that has the potential to resolve this disconnect by geographically distributing wind power generators in a manner that more closely mirrors the physical resource itself. To this end, technology development is focused on large arrays of small wind turbines that can harvest wind energy at low altitudes by using new concepts of biology-inspired engineering. This approach dramatically extends the reach of wind energy, as smaller wind turbines can be installed in many places that larger systems cannot, especially in built environments. Moreover, they have lower visual, acoustic, and radar signatures, and they may pose significantly less risk to birds and bats. These features can be leveraged to attain cultural acceptance and rapid adoption of this new technology, thereby enabling significantly faster achievement of state and national renewable energy targets than with existing technology alone. Favorable economics stem from an orders-of-magnitude reduction in the number of components in a new generation of simple, mass-manufacturable (even 3D-printable), vertical-axis wind turbines. However, this vision can only be achieved by overcoming significant scientific challenges that have limited progress over the past three decades. The following essay summarizes our approach as well as the opportunities and challenges associated with it, with the aim of motivating a concerted effort in basic and applied research in this area

Optimal Pandemic Influenza Vaccine Allocation Strategies for the Canadian Population

BACKGROUND: The world is currently confronting the first influenza pandemic of the 21(st) century. Influenza vaccination is an effective preventive measure, but the unique epidemiological features of swine-origin influenza A (H1N1) (pH1N1) introduce uncertainty as to the best strategy for prioritization of vaccine allocation. We sought to determine optimal prioritization of vaccine distribution among different age and risk groups within the Canadian population, to minimize influenza-attributable morbidity and mortality. METHODOLOGY/PRINCIPAL FINDINGS: We developed a deterministic, age-structured compartmental model of influenza transmission, with key parameter values estimated from data collected during the initial phase of the epidemic in Ontario, Canada. We examined the effect of different vaccination strategies on attack rates, hospitalizations, intensive care unit admissions, and mortality. In all scenarios, prioritization of high-risk individuals (those with underlying chronic conditions and pregnant women), regardless of age, markedly decreased the frequency of severe outcomes. When individuals with underlying medical conditions were not prioritized and an age group-based approach was used, preferential vaccination of age groups at increased risk of severe outcomes following infection generally resulted in decreased mortality compared to targeting vaccine to age groups with higher transmission, at a cost of higher population-level attack rates. All simulations were sensitive to the timing of the epidemic peak in relation to vaccine availability, with vaccination having the greatest impact when it was implemented well in advance of the epidemic peak. CONCLUSIONS/SIGNIFICANCE: Our model simulations suggest that vaccine should be allocated to high-risk groups, regardless of age, followed by age groups at increased risk of severe outcomes. Vaccination may significantly reduce influenza-attributable morbidity and mortality, but the benefits are dependent on epidemic dynamics, time for program roll-out, and vaccine uptake

Dose-Response of Aerobic Exercise on Cognition: A Community-Based, Pilot Randomized Controlled Trial

Epidemiological studies suggest a dose-response relationship exists between physical activity and cognitive outcomes. However, no direct data from randomized trials exists to support these indirect observations. The purpose of this study was to explore the possible relationship of aerobic exercise dose on cognition. Underactive or sedentary participants without cognitive impairment were randomized to one of four groups: no-change control, 75, 150, and 225 minutes per week of moderate-intensity semi-supervised aerobic exercise for 26-weeks in a community setting. Cognitive outcomes were latent residual scores derived from a battery of 16 cognitive tests: Verbal Memory, Visuospatial Processing, Simple Attention, Set Maintenance and Shifting, and Reasoning. Other outcome measures were cardiorespiratory fitness (peak oxygen consumption) and measures of function functional health. In intent-to-treat (ITT) analyses (n = 101), cardiorespiratory fitness increased and perceived disability decreased in a dose-dependent manner across the 4 groups. No other exercise-related effects were observed in ITT analyses. Analyses restricted to individuals who exercised per-protocol (n = 77) demonstrated that Simple Attention improved equivalently across all exercise groups compared to controls and a dose-response relationship was present for Visuospatial Processing. A clear dose-response relationship exists between exercise and cardiorespiratory fitness. Cognitive benefits were apparent at low doses with possible increased benefits in visuospatial function at higher doses but only in those who adhered to the exercise protocol. An individual’s cardiorespiratory fitness response was a better predictor of cognitive gains than exercise dose (i.e., duration) and thus maximizing an individual’s cardiorespiratory fitness may be an important therapeutic target for achieving cognitive benefits

Optical Propagation and Communication

Contains an introduction and reports on three research projects.Maryland Procurement Office Contract MDA 904-93-C4169Maryland Procurement Office Contract MDA 903-94-C6071U.S. Air Force - Office of Scientific Research Grant F49620-93-1-0604MIT Lincoln Laboratory Advanced Concepts Program Contract CX-16335U.S. Army Research Office Grant DAAH04-93-G-0399U.S. Army Research Office Grant DAAH04-93-G-018

DNA double-strand breaks induce H2Ax phosphorylation domains in a contact-dependent manner

Formation of γH2Ax serves as a checkpoint for double-strand break (DSB) repair pathways. Here the authors reveal via integrated chromatin analysis that γH2Ax domains are established by chromosomal contacts with the DSB site