Condition and condition duration indicator Patent

Electric network for monitoring temperatures, detecting critical temperatures, and indicating critical time duratio

Seismic displacement transducer Patent

Determining sway of buildings by low frequency device using pendulu

Device calibrates vibration transducer at amplitudes up to 20 g

A piezoelectric transducer provides accurate calibration of vibration amplitudes to 20 g. The calibration system uses an electromagnetically driven resonant beam to generate mechanical vibrations at a fixed frequency

Improved manual radio frequency direction finder

Antenna loop direction finder, consisting of two separate loops mounted rigidly together at right angles to each other, requires single rotation for operation. The loops, one for bearing, the other for sensing, are rotated manually. Sensing loop, in conjunction with nondirectional antenna, produces signal with directional pattern

Thermoset-thermoplastic aromatic polyamide containing N-propargyl groups

The compounds of the class of aromatic polyamides useful as matrix resins in the manufacture of composites or laminate fabrication were developed. The process for preparing this thermoplastic-thermoset polyamide system involves incorporating a latent crosslinking moiety along the backbone of the polyamide to improve the temperature range of fabrication thereof wherein the resin softens at a relatively low temperature (approx. 154 C) and subsequently sets-up or undergoes crosslinking when subjected to higher temperature (approx. 280 C)

Steering, knowledge and the challenge of governance evaluation: the case of National Health Service governance and reform in England

Drawing from ‘robust political economy’ (RPE) literature, we address evaluative questions concerning governance effectiveness in the face of complex, cross cutting problems. Central to RPE is the challenge of coordination, with its fundamental epistemological dimension requiring close attention to stakeholder knowledge about policy impacts. This focus contrasts with process-orientated analysis predominant in political science and public administration and enables holistic governance evaluation that draws from various, often demarcated, research fields. This is demonstrated through a focus on the evolution of health governance in England, particularly how diabetes services in England were affected by the 2012 Health and Social Care Act

Shuttle system ascent aerodynamic and plume heating

The shuttle program provided a challenge to the aerothermodynamicist due to the complexity of the flow field around the vehicle during ascent, since the configuration causes multiple shock interactions between the elements. Wind tunnel tests provided data for the prediction of the ascent design heating environment which involves both plume and aerodynamic heating phenomena. The approach for the heating methodology based on ground test firings and the use of the wind tunnel data to formulate the math models is discussed

Equilibrium Unemployment

A search-theoretic model of equilibrium unemployment is constructed and shown to be consistent with the key regularities of the labor market and business cycle. The two distinguishing features of the model are: (i) the decision to accept or reject jobs is modeled explicitly, and (ii) markets are incomplete. The model is well suited to address a number of interesting policy questions. Two such applications are provided: the impact of unemployment insurance, and the welfare costs of business cycles.Search; Incomplete Markets; Business Cycles; Unemployment Insurance; Welfare Costs of Business Cycles.

FGF2 is expressed in human and murine embryonic choroid plexus and affects choroid plexus cell behaviour

<p>Abstract</p> <p>Background</p> <p>Although fibroblast growth factor (Fgf) signalling plays crucial roles in several developing and mature tissues, little information is currently available on expression of Fgf2 during early choroid plexus development and whether Fgf2 directly affects the behaviour of the choroid plexus epithelium (CPe). The purpose of this study was to investigate expression of Fgf2 in rodent and human developing CPe and possible function of Fgf2, using <it>in vitro </it>models. The application of Fgf2 to brain <it>in vivo </it>can affect the whole tissue, making it difficult to assess specific responses of the CPe.</p> <p>Methods</p> <p>Expression of Fgf2 was studied by immunohistochemistry in rodent and human embryonic choroid plexus. Effects of Fgf2 on growth, secretion, aggregation and gene expression was investigated using rodent CPe vesicles, a three-dimensional polarized culture model that closely mimics CPe properties <it>in vivo</it>, and rodent CPe monolayer cultures.</p> <p>Results</p> <p>Fgf2 was present early in development of the choroid plexus both in mouse and human, suggesting the importance of this ligand in Fgf signalling in the developing choroid plexus. Parallel analysis of Fgf2 expression and cell proliferation during CP development suggests that Fgf2 is not involved in CPe proliferation <it>in vivo</it>. Consistent with this observation is the failure of Fgf2 to increase proliferation in the tri-dimensional vesicle culture model. The CPe however, can respond to Fgf2 treatment, as the diameter of CPe vesicles is significantly increased by treatment with this growth factor. We show that this is due to an increase in cell aggregation during vesicle formation rather than increased secretion into the vesicle lumen. Finally, Fgf2 regulates expression of the CPe-associated transcription factors, <it>Foxj1 </it>and <it>E2f5</it>, whereas transthyretin, a marker of secretory activity, is not affected by Fgf2 treatment.</p> <p>Conclusion</p> <p>Fgf2 expression early in the development of both human and rodent choroid plexus, and its ability to modulate behaviour and gene expression in CPe, supports the view that Fgf signalling plays a role in the maintenance of integrity and function of this specialized epithelium, and that this role is conserved between rodents and humans.</p

The relationship between CK and CV chondrites: a single parent body source?

The relationship between CK and CV3 chondrites is examined. Both groups may represent a single continuum and have been derived from the same parent body