The role of BIM in tackling obsolescence, climate change, and sustainability

Although the BIM technology is applicable to both new and existing buildings, it is arguably more established in the former than the latter. This is despite the fact that, in the UK alone, 70–80% of what has been built by 2010, is estimated to continue to exist for a number of decades to come: including the years 2020 and 2050 (the two main temporal deadlines in the Climate Change Act, 2008). In addition, this existing building stock is subject to obsolescence (both climate change-induced and non-climate change-associated) which in turn compromises sustainability. Thus, there are three notions that appear to be interwoven, i.e. Obsolescence, Climate Change, and Sustainability: the question is whether BIM can be exploited to address these. There has been only limited research work to explore the possible influence of BIM upon obsolescence, climate change, and sustainability as individual issues,and none reported, to-date, in terms of an approach to their collective consideration. This paper conceptually explores how BIM can be related with all three crucial notions simultaneously as well as discretely. It is argued that such studies can be particularly valuable in the face of escalating pressures in terms of future obsolescence risks, overwhelming evidence of climate change, and escalating sustainability agendas. The paper reviews current work that relates state-of-the-art BIM to the three notions, both separately and collectively, and thereby delineates the potential for BIM to play a role in addressing the three issues simultaneously

A study into different cell-level cooling strategies for cylindrical lithium-ion cells in automotive applications

Previous research has identified that the ageing rate and performance of lithium-ion cells is negatively influenced by unfavourable cell thermal conditions, specifically, high ambient temperatures and large in-cell temperature gradients. In this paper, the effectiveness of different cell cooling strategies on reducing the in-cell temperature gradient within cylindrical cells is analysed through the development of a 2-D transient bulk layer thermal model displaying anisotropic thermal conductivity. The model is validated against experimental temperature measurements in which the peak error of the simulation was found to be 2% and 5% for the experimental test drive cycle and constant 1C discharge respectively. Results indicate that radial cooling with air or singular tab cooling with liquid may be inadequate in limiting cell temperature gradients to below 5 ℃ for HEV type 32113 cells when subject to 4 loops of the US06 drive cycle

A novel approach to frequency support in a wind integrated power system

This paper discusses the impact of wind penetration on frequency control of a thermal dominated system considering Generation Rate Constraints (GRC) and dead band non-linearities. The hidden inertia emulation and coordinated operation of conventional power generation systems with wind energy can effectively alleviate the frequency excursions during sudden load disturbances. Conventional energy storage device like Flywheel Energy Storage (FES) system can be used in conjunction with wind integrated power system to overcome the intermittent nature of power generation. Thyristor Controlled Series Compensator (TCSC) is found to be effective in damping low frequency oscillations in weak tie-lines and supplement the frequency regulation. A stochastic population based evolutionary computation technique - Particle Swarm Optimization (PSO) is used to tune the controller gains. A strategy comprising inertia control, coordinated operation of conventional generation units with wind energy and TCSC-FES has been proposed to enhance the frequency regulation which is effective in controlling low frequency oscillations as established by the simulation results

Health Centre Surveys as a Potential Tool for Monitoring Malaria Epidemiology by Area and over Time

BACKGROUND: Presently, many malaria control programmes use health facility data to evaluate the impact of their interventions. Facility-based malaria data, although useful, have problems with completeness, validity and representativeness and reliance on routinely collected health facility data might undermine demonstration of the magnitude of the impact of the recent scaleups of malaria interventions. To determine whether carefully conducted health centre surveys can be reliable means of monitoring area specific malaria epidemiology, we have compared malaria specific indices obtained from surveys in health centres with indices obtained from cross-sectional surveys conducted in their catchment communities. METHODS: A series of age stratified, seasonal, cross-sectional surveys were conducted during the peak malaria transmission season in 2008 and during the following dry season in 2009 in six ecologically diverse areas in The Gambia. Participants were patients who attended the health centres plus a representative sample from the catchment villages of these health facilities. Parasitaemia, anaemia, attributable proportion of fever and anti-MSP1-(19) antibody seroprevalence were compared in the health facility attendees and community participants. RESULTS: A total of 16,230 subjects completed the study; approximately half participated in the health centre surveys and half in the wet season surveys. Data from both the health centre and community surveys showed that malaria endemicity in The Gambia is now low, heterogeneous and seasonal. In the wet season, parasitaemia, seroprevalence and fever prevalence were higher in subjects seen in the health centres than in the community surveys. Age patterns of parasitaemia, attributable proportions of fever and seroprevalence rates were similar in subjects who participated in the community and health centre surveys. CONCLUSION: Health centre surveys have potential as a surveillance tool for evaluating area specific malaria control activities and for monitoring changes in local malaria epidemiology over time

Direct evidence of lack of colocalisation of fluorescently labelled gold labels used in correlative light electron microscopy

Fluorescently labelled nanoparticles are routinely used in Correlative Light Electron Microscopy (CLEM) to combine the capabilities of two separate microscope platforms: fluorescent light microscopy (LM) and electron microscopy (EM). The inherent assumption is that the fluorescent label observed under LM colocalises well with the electron dense nanoparticle observed in EM. Herein we show, by combining single molecule fluorescent imaging with optical detection of the scattering from single gold nanoparticles, that for a commercially produced sample of 10 nm gold nanoparticles tagged to Alexa-633 there is in fact no colocalisation between the fluorescent signatures of Alexa-633 and the scattering associated with the gold nanoparticle. This shows that the attached gold nanoparticle quenches the fluorescent signal by ~95%, or less likely that the complex has dissociated. In either scenario, the observed fluorescent signal in fact arises from a large population of untagged fluorophores; rendering these labels potentially ineffective and misleading to the field

Practice characteristics of Emergency Department extracorporeal cardiopulmonary resuscitation (eCPR) programs in the United States: The current state of the art of Emergency Department extracorporeal membrane oxygenation (ED ECMO).

PURPOSE: To characterize the current scope and practices of centers performing extracorporeal cardiopulmonary resuscitation (eCPR) on the undifferentiated patient with cardiac arrest in the emergency department. METHODS: We contacted all US centers in January 2016 that had submitted adult eCPR cases to the Extracorporeal Life Support Organization (ELSO) registry and surveyed them, querying for programs that had performed eCPR in the Emergency Department (ED ECMO). Our objective was to characterize the following domains of ED ECMO practice: program characteristics, patient selection, devices and techniques, and personnel. RESULTS: Among 99 centers queried, 70 responded. Among these, 36 centers performed ED ECMO. Nearly 93% of programs are based at academic/teaching hospitals. 65% of programs are less than 5 years old, and 60% of programs perform ≤3 cases per year. Most programs (90%) had inpatient eCPR or salvage ECMO programs prior to starting ED ECMO programs. The majority of programs do not have formal inclusion and exclusion criteria. Most programs preferentially obtain vascular access via the percutaneous route (70%) and many (40%) use mechanical CPR during cannulation. The most commonly used console is the Maquet Rotaflow(®). Cannulation is most often performed by cardiothoracic (CT) surgery, and nearly all programs (\u3e85%) involve CT surgeons, perfusionists, and pharmacists. CONCLUSIONS: Over a third of centers that submitted adult eCPR cases to ELSO have performed ED ECMO. These programs are largely based at academic hospitals, new, and have low volumes. They do not have many formal inclusion or exclusion criteria, and devices and techniques are variable