59 research outputs found

    An Investigation into Self-Regulated Learning in a Virtual Classroom: A Higher Education Perspective

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    In the wake of the global pandemic COVID-19 and restrictions on human-to-human contacts higher education institutions have turned to e-learning as a solution to keep teaching and learning going Indeed aside from allowing the continuation of education during situations like that the other argument supporting e-learning is because of its social constructivist pedagogy and effective self-regulated learning However the claim of self-regulated learning in the context of e-learning has not empirically been validated Thus based on responses from 116 individuals using a mixed-method approach we sought to evaluate the effect of the use of the Learning Management System on students self-regulated learning Our findings indicate that despite the advantages of convenience and access to materials provided the system did not appear to regulate students learning with significant challenges of unreliable internet connectivity lack of key functionalities and features ultimately impeding optimal use The study discusses these findings and draws implications for theory and practic

    Role of the IRS-1 and/or -2 in the pathogenesis of insulin resistance in Dahl salt-sensitive (S) rats

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    Insulin resistance is a common finding in hypertensive humans and animal models. The Dahl salt-sensitive (S) rat is an ideal model of genetically predetermined insulin resistance and salt-sensitive hypertension. Along the insulin signaling pathway, the insulin receptor substrates 1 and 2 (IRS-1 and -2) are important mediators of insulin signaling. IRS-1 and/or IRS-2 genetic variant(s) and/or enhanced serine phosphorylation correlate with insulin resistance. The present commentary was designed to highlight the significance of IRS-1 and/or -2 in the pathogenesis of insulin resistance. An emphasis will be given to the putative role of IRS-1 and/or -2 genetic variant(s) and serine phosphorylation in precipitating insulin resistance

    Borrelioses, agentes e vetores

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