Using a smartphone acceleration sensor to study uniform and uniformly accelerated circular motions

The acceleration sensor of a smartphone is used for the study of the uniform and uniformly accelerated circular motions in two experiments. Data collected from both experiments are used for obtaining the angular velocity and the angular acceleration, respectively. Results obtained with the acceleration sensor are shown to be in good agreement with alternative methods, like using video recordings of both experiments and a physical model of the second experiment.Castro-Palacio, JC.; Velazquez, L.; Gómez-Tejedor, JA.; Manjón Herrera, FJ.; Monsoriu Serra, JA. (2014). Using a smartphone acceleration sensor to study uniform and uniformly accelerated circular motions. Revista Brasileira de Ensino de Fisica. 36(2):2315-2315. doi:10.1590/S1806-11172014000200015S2315231536

Measuring and Analyzing the resistivity break down of high temperature superconductors in a didactic laboratory

The behavior of superconductors manifested especially when measuring resistivity versus temperature above and below the critical temperature still appears as extremely interesting phenomena. The paper describe a several measurements preformed at didactic laboratory which demonstrate different superconductors\u2019 behavior and could be used as an introduction to further investigations. Comparison with models is shown as well as further important remarks for work planed for future are mad

High-Tech Kit \u2013 The set of advanced activities from the MOSEM project.

One of the most tangible outcomes of the MOSEM (Minds-On experimental equipment kits in Superconductivity and ElectroMagnetism for the continuing vocational training of upper secondary school physics teachers\u2014LLPLdV- TOI-2007-NO/165.009) project is the set of advanced experiments\u2014High-Tech Kit (HTK). The Kit contains the experiments, prototyped and tested among the project partners\u2019 schools and teacher training institutions. The activities are combined with e-modules comprising videos, animations, and modeling as well as with new support material for teachers and teacher seminars. The paper briefly shows some of the HTK materials as appropriate use of real and virtual multimedia in physics teaching and learning. The authors discuss the process of setting up same of the experiments and illustrate activities with the results of measurements obtained within

A randomized clinical trial of lipid metabolism modulation with fenofibrate for acute coronavirus disease 2019

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) cytotoxicity may involve inhibition of peroxisome proliferator-activated receptor alpha. Fenofibrate activates peroxisome proliferator-activated receptor alpha and inhibits SARS-CoV-2 replication in vitro. Whether fenofibrate can be used to treat coronavirus disease 2019 (COVID-19) infection in humans remains unknown. Here, we randomly assigned inpatients and outpatients with COVID-19 within 14 d of symptom onset to 145 mg of oral fenofibrate nanocrystal formulation versus placebo for 10 d, in a double-blinded fashion. The primary endpoint was a severity score whereby participants were ranked across hierarchical tiers incorporating time to death, mechanical ventilation duration, oxygenation, hospitalization and symptom severity and duration. In total, 701 participants were randomized to fenofibrate (n = 351) or placebo (n = 350). The mean age of participants was 49 ± 16 years, 330 (47%) were female, mean body mass index was 28 ± 6 kg/m2 and 102 (15%) had diabetes. Death occurred in 41 participants. Compared with placebo, fenofibrate had no effect on the primary endpoint. The median (interquartile range) rank in the placebo arm was 347 (172, 453) versus 345 (175, 453) in the fenofibrate arm (P = 0.819). There was no difference in secondary and exploratory endpoints, including all-cause death, across arms. There were 61 (17%) adverse events in the placebo arm compared with 46 (13%) in the fenofibrate arm, with slightly higher incidence of gastrointestinal side effects in the fenofibrate group. Overall, among patients with COVID-19, fenofibrate has no significant effect on various clinically relevant outcomes (NCT04517396). © 2022, The Author(s), under exclusive licence to Springer Nature Limited