328 research outputs found
0+ states and collective bands in 228Th studied by the (p,t) reaction
The excitation spectra in the deformed nucleus 228Th have been studied by
means of the (p,t)-reaction, using the Q3D spectrograph facility at the Munich
Tandem accelerator. The angular distributions of tritons were measured for
about 110 excitations seen in the triton spectra up to 2.5 MeV. Firm 0+
assignments are made for 17 excited states by comparison of experimental
angular distributions with the calculated ones using the CHUCK3 code.
Assignments up to spin 6+ are made for other states. Sequences of states are
selected which can be treated as rotational bands and as multiplets of
excitations. Moments of inertia have been derived from these sequences, whose
values may be considered as evidence of the two-phonon nature of most 0+
excitations. Experimental data are compared with interacting boson model and
quasiparticle-phonon model calculations and with experimental data for 229Pa.Comment: 21 pages, 14 figure
Breaking the generic mould? Grayson Perry, Channel 4 and the production of British arts television
© 2018, © The Author(s) 2018. This article examines Channel 4’s critically acclaimed series, Grayson Perry: Who Are You? (2014). Using interviews with those involved in making the series and textual analysis, we argue that the elements that contributed to the success of the series are inherently difficult to replicate due to the political economy of contemporary television production, thereby threatening the sustainability of the genre. However, while arts television rarely constitutes a commercial success in a traditional ratings sense, we outline the strategic value of the genre in contributing to Channel 4’s identity as Britain’s alternative public service broadcaster
Comparative studies on the structure of an upland African stream ecosystem
Upland stream systems have been extensively investigated in Europe, North America and Australasia and many of the central ideas concerning their function are based on these systems. One central paradigm, the river continuum concept is ultimately derived from those North American streams whose catchments remain forested with native vegetation. Streams of the tropics may or may not fit the model. They have been little studied. The Amani Nature Reserve in the East Usambara Mountains of north-eastern Tanzania offers an opportunity to bring these naturally forested systems to the attention of the ecological community. This article describes a comparison made between two lengths of the River Dodwe in this area. The work was carried out by a group of postgraduate students from eighteen European and African countries with advice from five staff members, as part of a course organised by the Tropical Biology Association. Rigorous efforts were made to standardise techniques, in a situation where equipment and laboratory facilities were very basic, through a management structure and deliberate allocation of work to specialists in each area.The article offers a summary of invertebrate communities found in the stream and its biomass. Crabs seem to be the key organism in both sections of the streams
Arrhythmogenic Phenotype in Dilated Cardiomyopathy: Natural History and Predictors of Life-Threatening Arrhythmias
BACKGROUND-\u2014Patients with dilated cardiomyopathy (DCM) may present with ventricular arrhythmias early in the disease course, unrelated to the severity of left ventricular dysfunction. These patients may be classified as having an arrhythmogenic DCM (ARDCM). We investigated the phenotype and natural history of patients with AR-DCM. METHODS AND RESULTS-\u2014Two hundred eighty-five patients with a recent diagnosis of DCM (median duration of the disease 1 month, range 0 to 7 months) and who had Holter monitoring at baseline were comprehensively evaluated and followed for 107 months (range 29 to 170 months). AR-DCM was defined by the presence of 651 of the following: unexplained syncope, rapid nonsustained ventricular tachycardia ( 655 beats, 65150 bpm), 651000 premature ventricular contractions/24 hours, and 6550 ventricular couplets/ 24 hours, in the absence of overt heart failure. The primary end points were sudden cardiac death (SCD), sustained ventricular tachycardia (SVT), or ventricular fibrillation (VF). The secondary end points were death from congestive heart failure or heart transplantation. Of the 285 patients, 109 (38.2%) met criteria for AR-DCM phenotype. AR-DCM subjects had a higher incidence of SCD/SVT/VF compared with non\u2013AR-DCM patients (30.3% vs 17.6%, P=0.022), with no difference in the secondary end points. A family history of SCD/SVT/VF and the AR-DCM phenotype were statistically significant and cumulative predictors of SCD/SVT/VF. CONCLUSIONS-\u2014One-third of DCM patients may have an arrhythmogenic phenotype associated with increased risk of arrhythmias during follow-up. A family history of ventricular arrhythmias in DCM predicts a poor prognosis and increased risk of SCD
Spectroscopy of 230Th in the (p,t) reaction
The excitation spectra in the deformed nucleus 230Th were studied by means of
the (p,t) reaction, using the Q3D spectrograph facility at the Munich Tandem
accelerator. The angular distributions of tritons are measured for about 200
excitations seen in the triton spectra up to 3.3 MeV. Firm 0+ assignments are
made for 16 excited states by comparison of experimental angular distributions
with the calculated ones using the CHUCK code. Additional assignments are
possible: relatively firm for 4 states and tentative also for 4 states.
Assignments up to spin are made for other states. Sequences of the states
are selected which can be treated as rotational bands and as multiplets of
excitations. Experimental data are compared with interacting boson model IBM)
and quasiparticle-phonon model (QPM) calculations.Comment: 35 pages in PDF, 14 figures in text and 8 figures in appendix
Extended version of the paper published in Phys.Re
Evidence for Quark-Hadron Duality in the Proton Spin Asymmetry
Spin-dependent lepton-nucleon scattering data have been used to investigate
the validity of the concept of quark-hadron duality for the spin asymmetry
. Longitudinally polarised positrons were scattered off a longitudinally
polarised hydrogen target for values of between 1.2 and 12 GeV and
values of between 1 and 4 GeV. The average double-spin asymmetry in
the nucleon resonance region is found to agree with that measured in
deep-inelastic scattering at the same values of the Bjorken scaling variable
. This finding implies that the description of in terms of quark
degrees of freedom is valid also in the nucleon resonance region for values of
above 1.6 GeV.Comment: 5 pages, 1 eps figure, table added, new references added, in print in
Phys. Rev. Let
The -dependence of the generalised Gerasimov-Drell-Hearn integral for the deuteron, proton and neutron
The Gerasimov-Drell-Hearn (GDH) sum rule connects the anomalous contribution
to the magnetic moment of the target nucleus with an energy-weighted integral
of the difference of the helicity-dependent photoabsorption cross sections. The
data collected by HERMES with a deuterium target are presented together with a
re-analysis of previous measurements on the proton. This provides a measurement
of the generalised GDH integral covering simultaneously the nucleon-resonance
and the deep inelastic scattering regions. The contribution of the
nucleon-resonance region is seen to decrease rapidly with increasing . The
DIS contribution is sizeable over the full measured range, even down to the
lowest measured . As expected, at higher the data are found to be in
agreement with previous measurements of the first moment of . From data on
the deuteron and proton, the GDH integral for the neutron has been derived and
the proton--neutron difference evaluated. This difference is found to satisfy
the fundamental Bjorken sum rule at GeV.Comment: 12 pages, 10 figure
Cataract-Causing Defect of a Mutant γ-Crystallin Proceeds through an Aggregation Pathway Which Bypasses Recognition by the α-Crystallin Chaperone
Background:
The transparency of the eye lens depends upon maintenance of the native state of the γ- and β-crystallins, which is aided by the abundant chaperones αA- and αB-crystallin. Mature onset cataract, the leading cause of blindness worldwide, involves the polymerization of covalently damaged or partially unfolded crystallins into light-scattering aggregates. A number of single amino acid substitutions and truncations of γ-crystallins result in congenital cataract in both humans and mice, though in many cases the coupling between the protein alterations and the accumulation of aggregates is poorly defined.
Methodology/Principal Findings:
We have studied the aggregation properties and chaperone interactions of human γD-crystallin carrying substitutions of two buried core mutants, I90F and V75D, which cause congenital cataract in mice. The in vitro aggregation pathway competing with productive refolding was not altered by either substitution. Furthermore, this aggregation pathway for both mutant proteins–originating from a partially folded intermediate–was efficiently suppressed by αB-crystallin. Thus the cataract pathology was unlikely to be associated with a direct folding defect. The native state of wild-type human γD-crystallin exhibited no tendency to aggregate under physiological conditions. However both I90F and V75D native-like proteins exhibited slow (days) aggregation to high molecular weight aggregates under physiological conditions. The perturbed conformation of I90F was recognized and bound by both αA and αB chaperones. In contrast, the aggregation derived from the perturbed state of V75D was not suppressed by either chaperone, and the aggregating species were not bound by the chaperone.
Conclusions/Significance:
The cataract phenotype of I90F in mice may be due to premature saturation of the finite α- crystallin pool. The V75D aggregation pathway and its escape from chaperone surveillance and aggregation suppression can account for the congenital cataract pathology of this mutant. Failure of chaperone recognition may be an important source of pathology for many other protein folding defects.National Eye Institute (Grant no. EY015834 )National Institutes of Health (U.S.) (Grant no. GM17980
First Measurement of the Tensor Structure Function of the Deuteron
The \Hermes experiment has investigated the tensor spin structure of the
deuteron using the 27.6 GeV/c positron beam of \Hera. The use of a tensor
polarized deuteron gas target with only a negligible residual vector
polarization enabled the first measurement of the tensor asymmetry \At and
the tensor structure function \bd for average values of the Bj{\o}rken
variable and of the squared four-momentum transfer . The quantities \At and \bd are found to be
non-zero. The rise of \bd for decreasing values of can be interpreted to
originate from the same mechanism that leads to nuclear shadowing in
unpolarized scattering
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