782 research outputs found

    Elaboration and characterization of Fe1–xO thin films sputter deposited from magnetite target

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    Majority of the authors report elaboration of iron oxide thin films by reactive magnetron sputtering from an iron target with Ar–O2 gas mixture. Instead of using the reactive sputtering of a metallic target we report here the preparation of Fe1–xOthin films, directly sputtered froma magnetite target in a pure argon gas flow with a bias power applied. This oxide is generally obtained at very low partial oxygen pressure and high temperature.We showed that bias sputtering which can be controlled very easily can lead to reducing conditions during deposition of oxide thin film on simple glass substrates. The proportion of wustite was directly adjusted bymodifying the power of the substrate polarization. Atomic force microscopy was used to observe these nanostructured layers. Mössbauer measurements and electrical properties versus bias polarization and annealing temperature are also reported

    Seamount influences on mid-water shrimps (Decapoda) and Gnathophausiids (Lophogastridea) of the South-West Indian ridge

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    This study was conducted under the UNDP/IUCN project, funded by the Global Environment Facility (GEF). The authors thank the School of Biology at the University of St Andrews and the National Environmental Research Council (NERC) for funding toward Tom B Letessier's PhD.Maintenance of often-observed elevated levels of pelagic diversity and biomass on seamounts, that are of relevance to conservation and fishery management, involves complex interactions between physical and biological variables that remain poorly understood. To untangle these biophysical processes we explore factors influencing the distribution of epi- and meso-pelagic (0–1000 m) micronektonic crustaceans (>15 mm; order Lophogastridea, family Gnathophausiidea; and order Decapoda) on and off seamounts along the South West Indian Ridge (SWIR, 27° to 42°S) and on a seamount off the Madagascar Ridge (31.6°S, 42.8°E). Thirty-one species of micronektic crustaceans were caught using mid-water trawls within the study are but there was no apparent latitude-related patterns in species richness or abundance. Species richness predicted by rarefraction curves and numerical abundance was highest in the vicinity (800 m). The dominant species assemblage comprised the shrimps Systellaspis debilis (37%) and Sergia prehensilis (34%), and was restricted to seamounts on the subtropical SWIR. Our observations suggest that the ‘oasis effect’ of seamounts conventionally associated with higher trophic levels is also applicable to pelagic micronektic crustaceans at lower trophic levels. We suggest that the enhanced biomass and species richness attributed is due to ‘habitat enrichment’, whereby seamounts provide favourable habitats for both pelagic and bentho-pelagic mid-water crustaceans.PostprintPeer reviewe

    Adherence to Direct Oral Anticoagulants in Patients With Non-Valvular Atrial Fibrillation: A Cross-National Comparison in Six European Countries (2008–2015)

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    Anticoagulants; Europe; Non valvular atrial fibrillationAnticoagulants; Europa; Fibril·lació auricular no valvularAnticoagulantes; Europa; Fibrilación auricular no valvularAims: To describe and compare the adherence to different direct oral anticoagulants (DOACs) in eight European databases representing six countries. Methods: Longitudinal drug utilization study of new users (≥18 years) of DOACs (dabigatran, rivaroxaban, apixaban) with a diagnosis of non-valvular atrial fibrillation (2008–2015). Adherence was examined by estimating persistence, switching, and discontinuation rates at 12 months. Primary non-adherence was estimated in BIFAP and SIDIAP databases. Results: The highest persistence rate was seen for apixaban in the CPRD database (81%) and the lowest for dabigatran in the Mondriaan database (22%). The switching rate for all DOACs ranged from 2.4 to 13.1% (Mondriaan and EGB databases, respectively). Dabigatran had the highest switching rate from 5.0 to 20.0% (Mondriaan and EGB databases, respectively). The discontinuation rate for all DOACs ranged from 16.0 to 63.9% (CPRD and Bavarian CD databases, respectively). Dabigatran had the highest rate of discontinuers, except in the Bavarian CD and AOK NORDWEST databases, ranging from 23.2 to 64.6% (CPRD and Mondriaan databases, respectively). Combined primary non-adherence for examined DOACs was 11.1% in BIFAP and 14.0% in SIDIAP. There were differences in population coverage and in the type of drug data source among the databases. Conclusion: Despite the differences in the characteristics of the databases and in demographic and baseline characteristics of the included population that could explain some of the observed discrepancies, we can observe a similar pattern throughout the databases. Apixaban was the DOAC with the highest persistence. Dabigatran had the highest proportion of discontinuers and switchers at 12 months in most databases (EMA/2015/27/PH).The project has received support from the European Medicines Agency under the Framework service contract (nr EMA/2015/27/PH) with regard to the reopening of competition no. 3. K. Janhsen (Witten/Herdecke University, Alfred-Herrhausen-Straße 50, 58448 Witten, Germany (UW/GH)) and A. Heeke (AOK NORDWEST, Kopenhagener Straße 1, 44269 Dortmund, Germany). R. Gerlach and M. Tauscher (National Association of Statutory Health Insurance Physicians of Bavaria, Elsenheimerstr. 39, MD-80687 Munich, Germany). The authors from the BIFAP database would like to acknowledge the excellent collaboration of the primary care general practitioners and pediatricians, and also the support of the regional governments to the database. This study is based in part on data from the ‘base de datos para la investigación Farmacoepidemiológica en Atención Primaria’ (BIFAP) fully financed by the Spanish Agency on Medicines and Medical Devices (AEMPS). The views and opinions expressed in this article are those of the authors and do not necessarily reflect the official policy or position of the EMA (European Medicines Agency) or one of its committees or working parties, or AEMPS (Agencia Española de Medicamentos y Productos Sanitarios). The authors thank Alethea Charlton for her support reviewing and editing the English. The authors thank SIDIAP (Sistema d’informació per al Desenvolupament de Investigació en Atenció Primària) for providing the data with respect to CPRD, approval of the study protocol was granted by the Independent Scientific Advisory Committee of the Medicines and Healthcare Products Regulatory Agency (protocol 17_089R)

    Intramontane lacustrine basins in the Siberian Altai: recorders of Cenozoic intracontinental tectonic and climatic events

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    The Altai Mountains are part of the vast intracontinental Central Asian orogenic system that formed during the Cenozoic as a distal effect of continued indentation of the Indian plate into the Eurasian continent. In the Siberian part of the Altai Mountains there is ample evidence to suggest that the pre-Cenozoic structural fabric of its basement is a controlling factor in the Cenozoic deformation and development of this intracontinental orogen. We give evidence that important Paleozoic fault zones were reactivated during the Cenozoic, particularly the Late Cenozoic and play a key role in the formation, evolution and current morphology of the Siberian Altai Mountains. Some of these faults are still active and recent and historic movements along them have triggered large seismic events. Late Cenozoic reactivation was expressed as pure thrust, oblique thrust to pure strike-slip faulting, resulting in an overall transpressive tectonic regime. In some cases, as for the graben basin of Lake Teletskoye, local, pure extensional stresses are responsible for its formation as we show in this contribution. Various other intramontane, tectonic basins developed. Some of these are very recent structures (the Teletskoye Basin) and are Pleistocene in age or younger, others have a prolonged history and contain a relatively complete Cenozoic sedimentary section, with evidence of Late Mesozoic precursor basins (Chuya Basin, Dzhulukul Basin). Some of these exhibit indications of marine incursions, but the basins are predominantly continental. The development of these basins is clearly associated with the location and Cenozoic reactivation of aforementioned long-lived fault zones in the Altai tectonic assemblage. Many of these basins accommodated fresh water lakes during their evolution and some are still the site of contemporary mountain lakes. Their stratigraphy, as well as the sedimentary architecture and basin morphology is manifestly influenced by and progresses with the stages of (Late) Cenozoic intracontinental mountain building and erosive denudation of the growing mountain ranges. Together with the clastic sedimentary input and the provenance characteristics, the intramontane Altai basin deposits are affected by evolving climatic conditions. These conditions dictate the main mode of erosion and transport, influence the sedimentary facies and supply rate and create the framework for a specific biocoenosis signature found in the fossil record. Our contribution reviews the data obtained over the last years from a selection of intramontane lacustrine basins in the Siberian Altai Mountains. We direct our attention in particular to the Teletskoye basin, the Chuya-Kurai Basin and the Dzhulukul Basin. We combine sedimentologic-stratigraphic data with basin architecture and morphology, and with basement geochronologic-thermochronologic constraints (apatite fission-track, U/Pb and Ar-dating) in order to show the potential of these basins as recorders of Cenozoic tectonic and climatic events in relation with basement features. While for example the data obtained from the Chuya Basin yields a continuous Cenozoic picture of deformation and climatic evolution of the Altai area, data from the Teletskoye Basin zooms in with higher resolution on the Pleistocene to Recent history. In general, all data point towards intensifying tectonic reactivation and mountain building of the Siberian Altai Mountains since the Middle Cenozoic, with clear peak activity in the Pliocene to Recent. This is demonstrated by the molassetype deposits in these basins, and by thermochronologic constraints. This activity is ongoing and structural, (paleo)seismic, geomorphologic and sedimentologic data corroborates this. The lacustrine Altai basins provide a record for a more or less continuous progressive cooling and aridification of the Altai area during the Cenozoic as manifested in the pollen fossil assemblages found in the Altai sediments

    Using neutron activation analysis to identify scales of interaction at Kinet Höyük, Turkey

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    We use NAA to characterize a relatively large archaeological ceramic sample from the Late Bronze Age to Hellenistic phases of Kinet Höyük, a coastal Turkish site in the Gulf of Iskenderun at the northeast corner of the Mediterranean Sea. The geographic extent of local Kinet wares (how local is local?) is established through comparison with sediment samples across the Kinet hinterland. Four major compositional groups are identified: local and locally imported wares, imports from Cypriot, and presumed Western Anatolian and Aegean centers, and imports that appear relatively homogenous elementally but comprise typologically diverse ceramics with attributions that range from Cyprus to the coastal mainland. Comparison with other published NAA studies for this site reinforces the elemental evidence for local production, and underlines the need for caution when assuming local production always equates with local clays particularly for coastal sites. We propose that the chronological distribution of the local and non-local groups provides a useful political economic proxy. The study indicates systemic and widespread political disruption and marginalization at the transition to the Late Iron Age in this region. © 2008 Elsevier Ltd. All rights reserved

    Karlstadter Positionspapier zum Schutz der Ackerwildkräuter. Erarbeitet von den Teilnehmerinnen und Teilnehmern der "Tagung zum Schutz der Ackerwildflora" am 25./26.6.2004 in Karlstadt am Main

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    Der Erhalt von Ackerwildkräutern, die historisch erst mit der Landbewirtschaftung in Mitteleuropa heimisch geworden sind, ist eine Kulturaufgabe, damit auch künftige Generationen die Arten- und Farbenvielfalt in der Kulturlandschaft erleben können

    G0^0 Electronics and Data Acquisition (Forward-Angle Measurements)

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    The G0^0 parity-violation experiment at Jefferson Lab (Newport News, VA) is designed to determine the contribution of strange/anti-strange quark pairs to the intrinsic properties of the proton. In the forward-angle part of the experiment, the asymmetry in the cross section was measured for e⃗p\vec{e}p elastic scattering by counting the recoil protons corresponding to the two beam-helicity states. Due to the high accuracy required on the asymmetry, the G0^0 experiment was based on a custom experimental setup with its own associated electronics and data acquisition (DAQ) system. Highly specialized time-encoding electronics provided time-of-flight spectra for each detector for each helicity state. More conventional electronics was used for monitoring (mainly FastBus). The time-encoding electronics and the DAQ system have been designed to handle events at a mean rate of 2 MHz per detector with low deadtime and to minimize helicity-correlated systematic errors. In this paper, we outline the general architecture and the main features of the electronics and the DAQ system dedicated to G0^0 forward-angle measurements.Comment: 35 pages. 17 figures. This article is to be submitted to NIM section A. It has been written with Latex using \documentclass{elsart}. Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment In Press (2007

    COMET-NARVAL ACQUISITION notice

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    SEP NESTER S2I translated by A.M. Dujardi
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