Gwal Pahari Acid: Isolation, Characterization of a New Soil Based Plant Growth Promoting Humic Acid

There are many “Save the Soil” movements highlighting the degradation of the soil due to excessive use of fertilizers, ground water contamination and environmental pollution. An alternative strategy is the use of humic acids from Organic Matter (OM) in soils. Humic acids help grow better vegetables, quality fruits like (peas, potatoes, tomatoes, pomegranates, mangoes), cereals, and pulses. These create supramolecular self– assemblies capable of retaining water and not allowing loss of minerals and ions. Humic acids isolated from soil, lignite and city solid waste are emerging as attractive sources for developing value added products from them. There is much interest in exploiting the commercial aspects in the energy sector of the economy as these new technologies could help in cleaning the environment as well. In this paper, the isolation of a new humic acid from the soil of Gwal Pahari, Gurgaon, Haryana, India is described. This water soluble, Ninhydrin positive Gwal Pahari Acid (GPA) contains thirteen chiral centers and contains both partly rigid and dynamic systems capable of exhibiting pseudo rotation. The proposed structure of this new humic acid is based on spectroscopic studies (e.g. FT-IR, UV-visible spectroscopy), detailed mass spectrometry, and very challenging 1H- NMR and 2D-NMR studies. Ion leakage studies on Arabidopsis thaliana have shown that the new compound provides protection to the plant, and greenhouse studies demonstrate that Gwal Pahari Acid brings about substantial growth in the tomato plant

Growth promoting properties of Mycobacterium and Bacillus on rice plants under induced drought

Management of drought stress through application of plant growth promoting rhizobacteria (PGPR) is now considered as an effective strategy in the present scenario of altered environmental conditions of the world. The aims and objectives of the present investigation was isolation, characterization and identification of some potential microbial resources (PGPR) from drought-affected upland rice fields of South Bengal followed by experimentation on the effect of isolated PGPR on drought induced rice seedlings. Selected isolates were isolated from rice field rhizospheric soils and tested for their PGPR activity, through phosphate solubilization, nitrogen fixation, IAA production and ACC deaminase activity. Then, the selected isolates were identified through 16S rDNA sequencing and phylogenetic analysis. Among the screened isolates two (isolate 1 and isolate 6) showing plant growth promoting traits, was applied on studied germplasm (IR64) to find out the influence of the applied organisms on rice growth and development under induced drought. Both organisms showed a positive influence (through increase in germination percentage, root growth, shoot growth, fresh weight and dry weight) on the studied rice growth and development under induced drought. Isolate 1 and 6 identified as species of Mycobacterium sp and Bacillus sp respectively through molecular taxonomy. Hence, these two isolates are expected to alleviate drought stress in the rice field for their nature of plant growth promotion under drought stress

Role of prophylactic midurethral sling in preventing post-operative stress urinary incontinence following repair of anterior vaginal wall prolapse

Objective: This study was conducted to find whether, among women without preoperative stress incontinence who underwent surgery for repair of anterior vaginal wall prolapse, the placement of a prophylactic midurethral mesh along with the prolapse correction surgery helped to reduce the incidence of post-operative stress urinary incontinence (POSUI). Materials & Methods: 145 women with anterior vaginal compartment prolapse were randomly assigned to receive either suitable corrective surgery for prolapse or corrective surgery along with concurrent placement of a prophylactic midurethral sling by a transobturator Prolene tape. The primary endpoint was urinary incontinence at three months and twelve months post surgery. Secondary outcomes included expected and unexpected adverse events. Results: At three months follow up the symptoms of urinary incontinence and/or positive cough test did not differ significantly between the two groups. But at twelve months, both the symptoms of urinary incontinence (9.59% versus 23.61%, p = 0.025, 95% CI = -25.93% to -2.11%, CMLE OR =0.346) and positive cough test (8.22% versus 25%, p = 0.007, 95% CI = -28.60% to -4.96%, CMLE OR = 0.271) were significantly lower in the study group compared to the control group. Expected and unexpected adverse events during operation and through the first year after surgery were comparable in both groups Conclusion: Placement of a midurethral sling by a Prolene mesh at the time of prolapse repair surgery significantly reduces the incidence of POSUI in women who were continent preoperatively. For this, the transobturator tape method is safe and effective with a low rate of complications

Periodontal Health-The Gordian Knot in Public Health: The Indian Standpoint

Oral health is an inherent part of public health and is intricately related to systemic health. The interdependency of oral health and systemic health merges at the knot called periodontal health. Systemic diseases like cardiovascular diseases, metabolic diseases, and autoimmune diseases affect periodontal tissues and there lies a bidirectional relationship between periodontitis and diabetes mellitus. Taking this into consideration, periodontal health maintainance is essential for better systemic health. With the advancing health complications in the present time and due to spatial disparities, periodontal health is taking the shape of a concerning public health problem. India is facing some definitive challenges in terms of the oral healthcare system. Periodontal health assessment needs introduction of oral health programmes focusing on periodontal assessment, oral health policies and promoting education regarding periodontal health. Continous surveilliance of the disease can help us in determing the prevalence of disease, disease progression, early diagnosis, and treatment. This review aims at finding the existing problems addressing periodontal health as a public health issue, key challenges, and possible ways out of this problem

Ethyl 2-[(2-oxo-2H-chromen-7-yl)oxy]acetate

In the title compound, C13H12O5, the mean plane of the 2H-chromene ring system (r.m.s deviation = 0.026 Å) forms a dihedral angle of 81.71 (6)° with the mean plane of ethyl 2-hydroxyacetate moiety (r.m.s deviation = 0.034 Å). In the crystal, C—H...O hydrogen bonds result in the formation of zigzag layers parallel to the bc plane

7-Hydroxymethyl-2-pivaloylamino-1,8-naphthyridine

In the title compound, C14H17N3O2, the mean plane of the 1,8-naphthyridine ring system (r.m.s deviation = 0.020 Å) forms a dihedral angle of 23.4 (1)° with the acetamide moiety (r.m.s deviation = 0.001 Å). The molecular structure is stabilized by an intramolecular O—H...N hydrogen bond, which generates an S(5) ring motif. In the crystal, molecules are linked into inversion dimers by pairs of N—H...O hydrogen bonds, generating 18-membered R22(18) ring motifs

A chemodosimeter for the ratiometric detection of hydrazine based on return of ESIPT and its application in live-cell imaging

A probe based on 2-(2′-hydroxyphenyl) benzothiazole (HBT) has been synthesized and used for the ratiometric detection of hydrazine. The probe is designed in such a way that the excited state intramolecular proton transfer (ESIPT) of the HBT moiety gets blocked. The chemodosimetric approach of hydrazine to the probe results in the recovery of the ESIPT by removal of a free HBT moiety through subsequent substitution, cyclization, and elimination processes. The probe is successfully demonstrated to enable the detection of hydrazine in live cells