The collision of India with Asia

We review the relative motion of India and Asia for the last 100 million years and present a revised reconstruction for the India-Antarctica-Africa-North America-Eurasia plate circuit based on published motion histories. Deformation of these continental masses during this time introduces uncertainties, as does error in oceanic isochron age and location. Neglecting these factors, the data ipso facto allow the inference that the motion of India relative to Eurasia was distinctly episodic. Although motion is likely to have varied more smoothly than these results would allow, the geological record also suggests a sequence of distinct episodes, at about the same times. Hence we suggest that no single event should be regarded as the collision of India with Asia. The deceleration of the Indian plate commencing at ~65. Ma is matched by an equally significant prior acceleration and this aspect must be taken into account in geodynamic scenarios proposed to explain the collision of India with Asia

Rolling open Earth’s deepest forearc basin

The Weber Deep—a 7.2-km-deep forearc basin within the tightly curved Banda arc of eastern Indonesia—is the deepest point of the Earth’s oceans not within a trench. Several models have been proposed to explain the tectonic evolution of the Banda arc in the context of the ongoing (ca. 23 Ma–present) Australia–Southeast Asia collision, but no model explicitly accounts for how the Weber Deep achieved its anomalous depth. Here we propose that the Weber Deep formed by forearc extension driven by eastward subduction rollback. Substantial lithospheric extension in the upper plate was accommodated by a major, previously unidentified, low-angle normal fault system we name the “Banda detachment.” High-resolution bathymetry data reveal that the Banda detachment is exposed underwater over much of its 120 km down-dip and 450 km lateral extent, having produced the largest bathymetric expression of any fault discernable in the world’s oceans. The Banda arc is a modern analogue for highly extended terranes preserved in the many regions that may similarly have “rolled open” behind migrating subduction zones

Where does India end and Eurasia begin?

The Indus Suture Zone is defined as the plate boundary between India and Eurasia. Here we document geochronological data that suggest that Indian rocks outcrop to the north of this suture zone. The inherited age spectrum of zircons from mylonitic gneiss collected in the southern part of the Karakorum Batholith is similar to those obtained from the Himalayan Terrane, the Pamir and is apparently Gondwanan in its affinity. These data are taken to indicate that the Karakorum Terrane was once a component of Gondwana, or at least derived from the erosion of Gondwanan material. Several continental ribbons (including the Karakorum Terrane) were rifted from the northern margin of Gondwana and accreted to Eurasia prior to India-Eurasia collision. Many therefore consider the Karakorum Terrane is the southern margin of Eurasia. However, we do not know if rifting led to the creation of a new microplate(s) or simply attenuated crust between Gondwana and these continental ribbons. Thus there is a problem using inherited and detrital age data to distinguish what is Indian and what is Eurasian crust. These findings have implications for other detrital/inherited zircon studies where these data are used to draw inferences about the tectonic history of various terranes around the world

Crustal strain partitioning and the associated earthquake hazard in the eastern Sunda-Banda Arc

We use Global Positioning System (GPS) measurements of surface deformation to show that the convergence between the Australian Plate and Sunda Block in eastern Indonesia is partitioned between the megathrust and a continuous zone of back-arc thrusting extending 2000 km from east Java to north of Timor. Although deformation in this back-arc region has been reported previously, its extent and the mechanism of convergence partitioning have hitherto been conjectural. GPS observations establish that partitioning occurs via a combination of anticlockwise rotation of an arc segment called the Sumba Block, and left-lateral movement along a major NE-SW strike-slip fault west of Timor. We also identify a westward extension of the back-arc thrust for 300 km onshore into East Java, accommodating slip of ∼6 mm/yr. These results highlight a major new seismic threat for East Java and draw attention to the pronounced seismic and tsunami threat to Bali, Lombok, Nusa Tenggara, and other coasts along the Flores Sea

Reconstructing subducted oceanic lithosphere by "reverse-engineering" slab geometries: The northern Philippine Sea Plate

Peer reviewe

Identification of undiagnosed atrial fibrillation patients using a machine learning risk prediction algorithm and diagnostic testing (PULsE-AI): Study protocol for a randomised controlled trial.

Atrial fibrillation (AF) is associated with an increased risk of stroke, enhanced stroke severity, and other comorbidities. However, AF is often asymptomatic, and frequently remains undiagnosed until complications occur. Current screening approaches for AF lack either cost-effectiveness or diagnostic sensitivity; thus, there is interest in tools that could be used for population screening. An AF risk prediction algorithm, developed using machine learning from a UK dataset of 2,994,837 patients, was found to be more effective than existing models at identifying patients at risk of AF. Therefore, the aim of the trial is to assess the effectiveness of this risk prediction algorithm combined with diagnostic testing for the identification of AF in a real-world primary care setting. Eligible participants (aged ≥30 years and without an existing AF diagnosis) registered at participating UK general practices will be randomised into intervention and control arms. Intervention arm participants identified at highest risk of developing AF (algorithm risk score ≥ 7.4%) will be invited for a 12‑lead electrocardiogram (ECG) followed by two-weeks of home-based ECG monitoring with a KardiaMobile device. Control arm participants will be used for comparison and will be managed routinely. The primary outcome is the number of AF diagnoses in the intervention arm compared with the control arm during the research window. If the trial is successful, there is potential for the risk prediction algorithm to be implemented throughout primary care for narrowing the population considered at highest risk for AF who could benefit from more intensive screening for AF. Trial Registration: NCT04045639

Spitzer Survey of the Large Magellanic Cloud, Surveying the Agents of a Galaxy's Evolution (SAGE) I: Overview and Initial Results

We are performing a uniform and unbiased, ~7x7 degrees imaging survey of the Large Magellanic Cloud (LMC), using the IRAC and MIPS instruments on board the Spitzer Space Telescope in order to survey the agents of a galaxy's evolution (SAGE), the interstellar medium (ISM) and stars in the LMC. The detection of diffuse ISM with column densities >1.2x10^21 H cm^-2 permits detailed studies of dust processes in the ISM. SAGE's point source sensitivity enables a complete census of newly formed stars with masses >3 solar masses that will determine the current star formation rate in the LMC. SAGE's detection of evolved stars with mass loss rates >1x10^-8 solar masses per year will quantify the rate at which evolved stars inject mass into the ISM of the LMC. The observing strategy includes two epochs in 2005, separated by three months, that both mitigate instrumental artifacts and constrain source variability. The SAGE data are non-proprietary. The data processing includes IRAC and MIPS pipelines and a database for mining the point source catalogs, which will be released to the community in support of Spitzer proposal cycles 4 and 5. We present initial results on the epoch 1 data with a special focus on the N79 and N83 region. The SAGE epoch 1 point source catalog has ~4 million sources. The point source counts are highest for the IRAC 3.6 microns band and decrease dramatically towards longer wavelengths consistent with the fact that stars dominate the point source catalogs and that the dusty objects, e.g. young stellar objects and dusty evolved stars that detected at the longer wavelengths, are rare in comparison. We outline a strategy for identifying foreground MW stars, that may comprise as much as 18% of the source list, and background galaxies, that may comprise ~12% of the source list.Comment: Accepted by the Astronomical Journa

Age- Matched Comparison of Children Hospitalized for 2009 Pandemic H1N1 Influenza with Those Hospitalized for Seasonal H1N1 and H3N2

BACKGROUND: A wide spectrum of clinical manifestation ranging from deaths to a mild course of disease has been reported in children infected with the 2009 pandemic H1N1 (pH1N1) influenza. METHODOLOGY/MAJOR FINDINGS: We conducted an age-matched control study comparing children hospitalized for pH1N1 with historic controls infected with seasonal H1N1 and H3N2 influenza to correct for the effect of age on disease susceptibility and clinical manifestations. We also compared children with pH1N1 to children concurrently admitted for seasonal influenza during the pandemic period to adjust for differences in health-seeking behavior during the pandemic or other potential bias associated with historic controls. There was no death or intensive care admission. Children with pH1N1 were more likely to have at least one risk condition for influenza, an underlying chronic pulmonary condition, more likely to have asthma exacerbation and to be treated with oseltamivir. There was no difference in other aspects of the clinical course or outcome. CONCLUSION: Disease manifestation of children hospitalized for pH1N1 infection was mild in our patient population

Spitzer survey of the Large Magellanic Cloud, surveying the agents of a galaxy's evolution (SAGE). IV. Dust properties in the interstellar medium

The goal of this paper is to present the results of a preliminary analysis of the extended infrared (IR) emission by dust in the interstellar medium (ISM) of the Large Magellanic Cloud (LMC). We combine Spitzer Surveying the Agents of Galaxy Evolution (SAGE) and Infrared Astronomical Satellite (IRAS) data and correlate the infrared emission with gas tracers of H I, CO, and Hα. We present a global analysis of the infrared emission as well as detailed modeling of the spectral energy distribution (SED) of a few selected regions. Extended emission by dust associated with the neutral, molecular, and diffuse ionized phases of the ISM is detected at all IR bands from 3.6 μm to 160 μm. The relative abundance of the various dust species appears quite similar to that in the Milky Way (MW) in all the regions we have modeled. We construct maps of the temperature of large dust grains. The temperature map shows variations in the range 12.1-34.7 K, with a systematic gradient from the inner to outer regions, tracing the general distribution of massive stars and individual H II regions as well as showing warmer dust in the stellar bar. This map is used to derive the far-infrared (FIR) optical depth of large dust grains. We find two main departures in the LMC with respect to expectations based on the MW: (1) excess mid-infrared (MIR) emission near 70 μm, referred to as the 70 μm excess, and (2) departures from linear correlation between the FIR optical depth and the gas column density, which we refer to as FIR excess emission. The 70 μm excess increases gradually from the MW to the LMC to the Small Magellanic Cloud (SMC), suggesting evolution with decreasing metallicity. The excess is associated with the neutral and diffuse ionized gas, with the strongest excess region located in a loop structure next to 30 Dor. We show that the 70 μm excess can be explained by a modification of the size distribution of very small grains with respect to that in the MW, and a corresponding mass increase of ≃13% of the total dust mass in selected regions. The most likely explanation is that the 70 μm excess is due to the production of large very small grains (VSG) through erosion of larger grains in the diffuse medium. This FIR excess could be due to intrinsic variations of the dust/gas ratio, which would then vary from 4.6 to 2.3 times lower than the MW values across the LMC, but X_(CO) values derived from the IR emission would then be about three times lower than those derived from the Virial analysis of the CO data. We also investigate the possibility that the FIR excess is associated with an additional gas component undetected in the available gas tracers. Assuming a constant dust abundance in all ISM phases, the additional gas component would have twice the known H I mass. We show that it is plausible that the FIR excess is due to cold atomic gas that is optically thick in the 21 cm line, while the contribution by a pure H_2 phase with no CO emission remains a possible explanation