1,036 research outputs found
Dirac Gauginos in General Gauge Mediation
We extend the formulation by Meade, Seiberg and Shih of general gauge
mediation of supersymmetry breaking to include Dirac masses for the gauginos.
These appear through mixing of the visible sector gauginos with additional
states in adjoint representations. We illustrate the method by reproducing the
existing results in the literature for the gaugino and sfermion masses when
preserving R-symmetry. We then explain how the generation of same sign masses
for the two propagating degrees of freedom in the adjoint scalars can be
achieved. We end by commenting on the use of the formalism for describing U(1)
mixing.Comment: 22 pages, no figures. V2: minor corrections
One-loop adjoint masses for branes at non-supersymmetric angles
This proceeding is based on arXiv:1105.0591 [hep-th] where we consider
breaking of supersymmetry in intersecting D-brane configurations by slight
deviation of the angles from their supersymmetric values. We compute the masses
generated by radiative corrections for the adjoint scalars on the brane
world-volumes. In the open string channel, the string two-point function
receives contributions only from the infrared limits of N~4 and N~2
supersymmetric configurations, via messengers and their Kaluza-Klein
excitations, and leads at leading order to tachyonic directions.Comment: 15 pages, 5 figures. Contribution to the proceedings of the Corfu
Summer Institute 2011 School and Workshops on Elementary Particle Physics and
Gravity, September 4-18 2011 Corfu, Greec
Dark Matter and Dark Forces from a supersymmetric hidden sector
We show that supersymmetric "Dark Force" models with gravity mediation are
viable. To this end, we analyse a simple string-inspired supersymmetric hidden
sector model that interacts with the visible sector via kinetic mixing of a
light Abelian gauge boson with the hypercharge. We include all induced
interactions with the visible sector such as neutralino mass mixing and the
Higgs portal term. We perform a detailed parameter space scan comparing the
produced dark matter relic abundance and direct detection cross sections to
current experiments.Comment: 40 pages, 11 figures comprising 21 plots. 4Mb total size. v2: figures
and references updated; typos removed; some extra explanations added. Matches
version published in PR
A Three-dimensional Printed Low-cost Anterior Shoulder Dislocation Model for Ultrasound-guided Injection Training.
Anterior shoulder dislocations are the most common, large joint dislocations that present to the emergency department (ED). Numerous studies support the use of intraarticular local anesthetic injections for the safe, effective, and time-saving reduction of these dislocations. Simulation training is an alternative and effective method for training compared to bedside learning. There are no commercially available ultrasound-compatible shoulder dislocation models. We utilized a three-dimensional (3D) printer to print a model that allows the visualization of the ultrasound anatomy (sonoanatomy) of an anterior shoulder dislocation. We utilized an open-source file of a shoulder, available from embodi3D® (Bellevue, WA, US). After approximating the relative orientation of the humerus to the glenoid fossa in an anterior dislocation, the humerus and scapula model was printed with an Ultimaker-2 Extended+ 3D® (Ultimaker, Cambridge, MA, US) printer using polylactic acid filaments. A 3D model of the external shoulder anatomy of a live human model was then created using Structure Sensor®(Occipital, San Francisco, CA, US), a 3D scanner. We aligned the printed dislocation model of the humerus and scapula within the resultant external shoulder mold. A pourable ballistics gel solution was used to create the final shoulder phantom. The use of simulation in medicine is widespread and growing, given the restrictions on work hours and a renewed focus on patient safety. The adage of see one, do one, teach one is being replaced by deliberate practice. Simulation allows such training to occur in a safe teaching environment. The ballistic gel and polylactic acid structure effectively reproduced the sonoanatomy of an anterior shoulder dislocation. The 3D printed model was effective for practicing an in-plane ultrasound-guided intraarticular joint injection. 3D printing is effective in producing a low-cost, ultrasound-capable model simulating an anterior shoulder dislocation. Future research will determine whether provider confidence and the use of intraarticular anesthesia for the management of shoulder dislocations will improve after utilizing this model
Inter-Intra Molecular Dynamics as an Iterated Function System
The dynamics of units (molecules) with slowly relaxing internal states is
studied as an iterated function system (IFS) for the situation common in e.g.
biological systems where these units are subjected to frequent collisional
interactions. It is found that an increase in the collision frequency leads to
successive discrete states that can be analyzed as partial steps to form a
Cantor set. By considering the interactions among the units, a self-consistent
IFS is derived, which leads to the formation and stabilization of multiple such
discrete states. The relevance of the results to dynamical multiple states in
biomolecules in crowded conditions is discussed.Comment: 7 pages, 7 figures. submitted to Europhysics Letter
Dirac Gauginos and Kinetic Mixing
We present formulae for the calculation of Dirac gaugino masses at leading
order in the supersymmetry breaking scale using the methods of analytic
continuation in superspace and demonstrate a link with kinetic mixing, even for
non-abelian gauginos. We illustrate the result through examples in field and
string theory. We discuss the possibility that the singlet superfield that
gives the U(1) gaugino a Dirac mass may be a modulus, and some consequences of
the D-term coupling to the scalar component. We give examples of possible
effects in colliders and astroparticle experiments if the modulus scalar
constitutes decaying dark matter.Comment: 17 pages, no figures. Published version, one reference adde
Empirical entropic contributions in computational docking: Evaluation in APS reductase complexes
The results from reiterated docking experiments may be used to evaluate an empirical vibrational entropy of binding in ligand–protein complexes. We have tested several methods for evaluating the vibrational contribution to binding of 22 nucleotide analogues to the enzyme APS reductase. These include two cluster size methods that measure the probability of finding a particular conformation, a method that estimates the extent of the local energetic well by looking at the scatter of conformations within clustered results, and an RMSD-based method that uses the overall scatter and clustering of all conformations. We have also directly characterized the local energy landscape by randomly sampling around docked conformations. The simple cluster size method shows the best performance, improving the identification of correct conformations in multiple docking experiments. © 2008 Wiley Periodicals, Inc. J Comput Chem, 2008Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/60220/1/20936_ftp.pd
The RCSB Protein Data Bank: views of structural biology for basic and applied research and education.
The RCSB Protein Data Bank (RCSB PDB, http://www.rcsb.org) provides access to 3D structures of biological macromolecules and is one of the leading resources in biology and biomedicine worldwide. Our efforts over the past 2 years focused on enabling a deeper understanding of structural biology and providing new structural views of biology that support both basic and applied research and education. Herein, we describe recently introduced data annotations including integration with external biological resources, such as gene and drug databases, new visualization tools and improved support for the mobile web. We also describe access to data files, web services and open access software components to enable software developers to more effectively mine the PDB archive and related annotations. Our efforts are aimed at expanding the role of 3D structure in understanding biology and medicine
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