3,206 research outputs found
Does The Use Of Probiotics Treat Abdominal Pain In Children Between The Ages Of 4 And 18 With Irritable Bowel Syndrome?
Get PDFOBJECTIVE: The objective of this selective EBM review is to determine whether or not the use of probiotics treat abdominal pain in children between the ages of 4 and 18 with irritable bowel syndrome.
STUDY DESIGN: Systemic review of three randomized controlled trials (RCTs) published after 2007, all English language.
DATA SOURCES: All three randomized controlled trials were found on PubMed and were selected based on relevance to the proposed clinical question.
OUTCOMES MEASURED: Main outcomes measured were duration with and without abdominal pain, severity of pain, postprandial swelling, belching-abdominal distention, difficulty in defecation, urgent defecation, and feeling of incomplete defecation. Outcomes were measured by using Wonger-Baker FACES pain rating scale, five-point likert scale, and a self-reported questionnaire.
RESULTS: Two studies found no significant improvement in abdominal pain or discomfort when comparing probiotics to placebo when treating irritable bowel syndrome. One study found a significant improvement in abdominal pain when comparing probiotics to placebo. When looking at efficacy of probiotics, two studies had a relatively low number needed to treat.
CONCLUSION: From the three randomized controlled trials, it can be concluded that treating children with irritable bowel syndrome between the age of 4 and 16 with probiotics is inconclusive. Further research is warranted
Numerical computation of transonic loads on Ariane 5ECA during launch phase
Get PDFThe objective of the thesis has been analyze the transonic loads acting on the launcher Ariane 5ECA at different altitudes, velocities and angles of attack during the launch phase. It has been possible by several simulations with STAR-CCM+.The launcher has been designed with Solidworks also to permit the simulation of the jet leaving the rocket engines. In this way it was possible to obtain information of pressure and mach number variation inside the engines. Finally, the thesis has been focused on the fairing and the frequency domain has been obtained
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