Diseño, construcción y análisis de funcionamiento inicial de un sistema de acuaponía que combina un estanque ornamental con un jardín vertical exterior

La sociedad avanza en busca de un modelo de ciudad más sostenible donde poder vivir con un entorno lo más natural posible, cuestión que no siempre está al alcance de muchos habitantes. Para disminuir los problemas tales como contaminación atmosférica, ruido, consumo energético descontrolado, gestión de recursos naturales, enfermedades provocadas por el entorno artificial en el que hoy en día vive la mayoría de la población, surge la integración de la vegetación en zonas urbanas mediante el uso de la jardinería. En la naturación de edificios se utilizan techos verdes y jardines verticales. El método del plano vertical ya se usaba hace siglos con el ajardinamiento de fachadas a través de macetas y plantas trepadoras. Los jardines verticales más actuales están constituidos por una estructura soporte sobre la cual se instala el medio de crecimiento que puede ser hidropónico o semihidropónico, acompañado de un sistema de riego y fertirrigación que aporta los nutrientes a las plantas, además de un sistema de control y automatización. Los jardines verticales pueden integrarse en sistemas acuapónicos lo cual reduciría considerablemente el suministro de agua y nutrientes al jardín, haciéndolo de este modo más sostenible. De manera general, un sistema acuapónico combina la producción de peces, llamada acuicultura, y el cultivo de plantas en un sistema hidropónico. Los desechos metabólicos producidos por los peces son absorbidos por las plantas y así el agua quedaría depurada. En este trabajo se ha diseñado, construido y analizado el funcionamiento inicial de un sistema acuapónico enfocado a la jardinería en el que se ha combinado un estanque ornamental y un jardín vertical exterior.Grado en Ingeniería Agrícol

On demand translation for querying incompletely aligned datasets

More and more users aim at taking advantage of the existing Linked Open Data environment to formulate a query over a dataset and to then try to process the same query over different datasets, one after another, in order to obtain a broader set of answers. However, the heterogeneity of vocabularies used in the datasets on the one side, and the fact that the number of alignments among those datasets is scarce on the other, makes that querying task difficult for them. Considering this scenario we present in this paper a proposal that allows on demand translations of queries formulated over an original dataset, into queries expressed using the vocabulary of a targeted dataset. Our approach relieves users from knowing the vocabulary used in the targeted datasets and even more it considers situations where alignments do not exist or they are not suitable for the formulated query. Therefore, in order to favour the possibility of getting answers, sometimes there is no guarantee of obtaining a semantically equivalent translation. The core component of our proposal is a query rewriting model that considers a set of transformation rules devised from a pragmatic point of view. The feasibility of our scheme has been validated with queries defined in well known benchmarks and SPARQL endpoint logs, as the obtained results confirm

Her2-Positive and Microsatellite Instability Status in Gastric Cancer—Clinicopathological Implications

Institutional Review Board Statement: The study was conducted according to the Declaration of Helsinki, national and international guidelines and approved by the Provincial Research Ethics Committee of Malaga, Spain (approval 21 February 2019, number TFG-NCCG-2019). Informed Consent Statement: All the subjects provided written informed consent before participating in the study. Written informed consent for publication obtained from participating patients who can be identified. Data Availability Statement: The data that support the findings of this study are available from the corresponding author upon reasonable request. Acknowledgments: The authors would like to thank Maria Repice for her help with the English version of the text.Gastric cancer (GC) is one of the leading causes of cancer-related death. The combination of new molecular classifications with clinicopathological data could contribute to the individualization of patients and to the development of new therapeutic strategies. We examined the various associations in two molecular types of GC: HER2-positive (human epidermal growth factor receptor 2) and microsatellite instability (MSI), assessing their influence on treatment and prognosis. A retrospective study of 142 GC patients was performed with molecular characterization through HER2 overexpression and DNA repair protein expression for MSI. The percentage of HER2-positive tumors was 13.4%, predominantly in men. Correlations were found with intestinal type, metastases, advanced stages and chemotherapy. Almost 75% of HER2-positive patients died. MSI occurred in 16.2%, associated with advanced age, female sex, distal location and intestinal type. These patients had few metastases and low stages. The percentage of deaths was higher among MSI patients who received perioperative chemotherapy. The determination of HER2 and MSI status in GC is important for their association with specific clinicopathological features and for their prognostic and predictive value.This research was financially supported by the Department of Human Physiology, Human Histology, Anatomical Pathology and Physical Education (Histology Unit), University of Malaga and by the Department of Anatomical Pathology, Virgen de la Victoria University Hospital

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Introducción: desde las primeras llamadas de alerta de la Asamblea Mundial de la Salud en el siglo pasado,  las bajas tasas de incidencia y de duración de la lactancia materna son reconocidas como un problema de  salud pública. Objetivo: caracterizar la práctica de la lactancia materna exclusiva y parcial en el  departamento de Caldas en el año 2010 según variables sociodemográficas. Materiales y métodos: estudio  descriptivo de corte transversal en una muestra probabilística de 1.316 madres residentes en la zona urbana  (70,5%) y rural (29,5%) de 26 municipios de Caldas, sin incluir a Manizales. La muestra se calculó a partir de  una prueba piloto en 200 hogares de la zona  de Caldas, con la cual se encontró un promedio de duración de  lactancia materna exclusiva de 4,7±2,4 meses. Con este dato se calculó la muestra para poblaciones finitas,  con un error del 3% y una confianza del 95% a partir del total de nacimientos vivos en 2009 en Caldas.  Resultados: la mediana de duración de la lactancia materna exclusiva en Caldas fue de tres meses; fue  inferior en 1,2 meses a la meta propuesta por el Plan Nacional de Seguridad Alimentaria y Nutricional de  Colombia para la lactancia materna exclusiva, establecida en 4,2 meses, pero superior a la nacional en 1,2  meses (ENSIN 2010). La mediana de la lactancia materna parcial o con suministro de alimentos fue de cuatro  meses. Conclusión: los municipios con las medianas más altas de lactancia materna exclusiva fueron  Chinchiná y Marulanda y los que presentaron las medianas menores fueron Pácora, La Merced y Belalcázar. Introduction: Since the first alert calls from the World Health Assembly the last century, low rates of  incidence and duration of breastfeeding are recognized as a public health problem. Objective: to  characterize the practice of partial and exclusive breastfeeding in the Department of Caldas in the year 2010  according to social-demographic variables. Materials and methods: descriptive cross-section study in a  1,316 resident mothers probabilistic sampling living in the urban area (70.5%) and rural (29.5%) of 26  municipalities of Caldas, excluding Manizales. The sample was calculated from a pilot test in 200 homes in the urban area in the South Centre sub-region of Caldas, with which an average duration of exclusive  breastfeeding for 4.7 ± 2, 4 months was found. With this data the sample for finite populations was  calculated, with a 3% error rate and a 95% confidence rate from the total number of live births in Caldas in  2009. Results: The median duration of exclusive maternal breastfeeding in Caldas was three months. It was  inferior in 1.2 months to the goal proposed by the Colombian National Food and Nutritional Security Plan for  exclusive mother breastfeeding established in 4.2 months, but it was superior to the national goal  established in 1.2 months (ENSIN 2010). The median of partial mother breastfeeding or with other food  supply was 4 months. Conclusion: the municipalities with the highest median percentile of exclusive  breastfeeding were Chinchiná and Marulanda and those with the lowest median were Pácora, La Merced and  Belalcázar

Assessing the influence of isotopic composition of water on that of clay minerals during chemical treatments.

The isotopic composition of hydrogen in authigenic minerals is a useful tool to reconstruct past paleo-environments. Clay minerals are an important component of authigenic minerals in soils and sediments but they usually occur with other compounds that must be eliminated before the analysis, such as organic matter and carbonates. Thus, various “pre-treatments” are used, generally involving dilute HCl and H2O2 solutions in water. In this work, the influence of the isotopic composition of the water used in these pre-treatment solutions is assessed, using ten different samples of clay minerals. The isotopic composition of hydrogen was measured in each sample after HCl pre-treatment alone, H2O2 pre-treatment alone and both HCl and H2O2 pre-treatments in sequence, using two types of water in the pre-treatment solutions: one 2H-enriched and one 2H-depleted. The results indicate some influence of the isotopic composition of the water on the clay minerals after pre-treatment. In general, the samples showed significant alteration by HCl pre-treatment and negligible alteration by H2O2 pre-treatment. A pure kaolinite reference material did not show any change by chemical pre-treatment while a smectite reference material did show significant effects. Other samples (Ethiopian lacustrine sediment samples and Spanish cave sediments) showed important differences, which also depend on clay mineralogy. Thus, mineralogy seems to be the main cause of the variability in the alteration, especially the quantity of smectite. In addition, this result challenges the utility of clay minerals for isotope studies in acid conditions, such as in acidic soils, to reconstruct past environments and, therefore, climate changes.This study was developed during a stay supported by predoctoral mobility grant from the Spanish MINECO. Financial support for this work was obtained from MINECO Grant CGL2015-65387-C3-3-P. I. Campaña was the beneficiary of a predoctoral FPI Grant from the Spanish MINECO. We thank Jessica Wilson at the University of South Florida School of Geosciences who supported the isotopic analysis. J.G. Wynn was supported by an NSF IR/D program. Special thanks to the local resident of Burgos that help us remove the car from a mud puddle. // Funding for open access charge: Universidad de Málaga / CBU

Antibacterial and Antiparasitic Activity of Propyl-Propane- Thiosulfinate (PTS) and Propyl-Propane-Thiosulfonate (PTSO) from Allium cepa against Gilthead Sea Bream Pathogens in In Vitro and In Vivo Studies

The use of phytogenic extracts is considered a sustainable strategy for the prevention of fish diseases, including Alliaceae as a potential option due to their variety of bioactive compounds. In this study, we analyzed the antibacterial and antiparasitic potential of propyl-propanethiosulfinate (PTS) and propyl-propane-thiosulfonate (PTSO) from onions. The in vitro activity against Pseudomonas anguilliseptica, Tenacibaculum maritimum, and Photobacterium damselae of both compounds was tested. In addition, the viability of Sparicotyle chrysophrii larvae was evaluated. Moreover, a diet that consisted of a blend of PTS/PTSO (ALLIUM) was used. A total of 90 gilthead sea bream juveniles were tested against P. damselae subsp. Piscicida after 12 weeks of dietary administration. Furthermore, 150 fish with a rate of 10–15 parasites/fish were fed for 21 days and the number of gill parasites was recorded. All strains were sensitive to both compounds. PTSO showed the highest inhibitory effect against all target strains, while PTS showed higher effectiveness against S. chrysophrii. Fish from ALLIUM group presented the highest probability of survival, increasing up to 91.1%, whereas in the control group, the probability of survival was 66.7%. The number of parasites in the gilthead sea bream decreased in the ALLIUM group over time. These results suggest the inclusion of PTS and PTSO in feed as a natural strategy to prevent antibacterial and antiparasitic fish diseases.Centre for the Development of Industrial Technology (CDTI) 20170032 CER-2021101

Revision of TD1 and TD2 stratigraphic sequence of Gran Dolina cave (Sierra de Atapuerca, Spain)

Gran Dolina es una cueva rellena por al menos 25 m de sedimentos pleistocenos dividido en 12 unidades litoestratigráficas y 19 facies sedimentarias. Estas facies sedimentarias se han dividido entre facies alóctonas, definidas como entradas de sedimentos desde el exterior, y facies autóctonas, definidas como sedimentos generadas dentro del karst; sin embargo, esta clasificación de facies ha sido cuestionada en trabajos recientes. En este estudio se ha descrito en detalle las unidades TD1 y TD2 de Gran Dolina y se ha evaluado la idoneidad del uso de facies autóctonas. Para ello, se ha estudiado la sección estratigráfica de la excavación arqueológica, combinando observaciones de campo con análisis de laboratorio (tamizado, difracción láser y DRX) para caracterizar la textura y estructura de los sedimentos. A partir de estos estudios, se han identificado un total de 8 facies sedimentarias, y se han separado la unidad TD1 en dos sub-unidades y 13 niveles, y la unidad TD2 en tres sub-unidades. La asociación de facies indica una sucesión de fases freáticas y vadosas que definiría conjuntamente condiciones epifreáticas en el interior de la cueva, relacionadas con la transición entre la terraza T3 y la terraza T4 del valle del río Arlanzón. Por tanto, se propone el término facies de interior (y facies de entrada en vez de facies alóctonas) para definir los sedimentos de las unidades de TD1 y TD2 de Gran Dolina, ya que el análisis de facies indica transporte de los sedimentos por corrientes subterráneas.This study was supported by the project PGC2018-093925-B-C31 of the Spanish Ministry of Science and Innovation, Spanish State Research Agency and FEDER funds from the UE. Project PID2021-122355NB-C33 financed by MCIN/AEI/10.13039/501100011033/FEDER, UE. Funding for open access charge: Universidad de Málaga/CBUA. I. Campaña is the beneficiary of a postdoctoral grant from Junta de Andalucía. This work has benefited from discussion with Mathieu Duval, Lucía Bermejo, Lucía Ojeda and Sergio Durán. The constructive comments made by one anonymous reviewer and Dr. Ivan Martini contributed to improve the manuscript

Cannabis use and involuntary admission may mediate long-term adherence in first-episode psychosis patients: a prospective longitudinal study

Background: This study aimed to examine factors associated with treatment adherence in first-episode psychosis (FEP) patients followed up over 8 years, especially involuntary first admission and stopping cannabis use. Methods: This prospective, longitudinal study of FEP patients collected data on symptoms, adherence, functioning,and substance use. Adherence to treatment was the main outcome variable and was categorized as ‘good’ or ‘bad’. Cannabis use during follow-up was stratified as continued use, stopped use, and never used. Bivariate and logistic regression models identified factors significantly associated with adherence and changes in adherence over the 8-year follow-up period. Results: Of the 98 FEP patients analyzed at baseline, 57.1% had involuntary first admission, 74.4% bad adherence,and 52% cannabis use. Good adherence at baseline was associated with Global Assessment of Functioning score (p = 0.019), Hamilton Depression Rating Scale score (p = 0.017) and voluntary admission (p < 0.001). Adherence patterns over 8 years included: 43.4% patients always bad, 26.1% always good, 25% improved from bad to good. Among the improved adherence group, 95.7% had involuntary first admission and 38.9% stopped cannabis use. In the subgroup of patients with bad adherence at baseline, involuntary first admission and quitting cannabis use during follow up were associated with improved adherence. Conclusions: The long-term association between treatment adherence and type of first admission and cannabis use in FEP patients suggest targets for intervention to improve clinical outcomes

Reconstructing depositional environments through cave interior facies: The case of Galería Complex (Sierra de Atapuerca, Spain)

This work showed that cave sediments are useful for geomorphologic studies and for reconstructing depositional environments. While the cave entrance facies have been extensively studied for their relationship with the fossil and archaeological record, the cave interior facies have received much less attention, although they can provide much information on the geomorphological evolution of the karst. This work presents the stratigraphic and sedimentological study of a section >6 m thick and 10 m long of cave interior sediments of Galería Complex (Sierra de Atapuerca, Spain). Galería Complex is a cavity infill of the Sierra de Atapuerca (Spain), composed of three sections filled by at least 30 m of Pleistocene sediments. This sequence is divided into 5 lithostratigraphic units named from bottom to top: GI – GV. GI unit is 19 m thick of interior facies in the base of the Galería Complex, divided into two sub-unit, GIa and GIb, by the Matuyama-Bruhnes paleomagnetic boundary. GI unit shows an issue with the chronology since has uncoherent between TT-OSL and ESR/U-series and paleomagnetism dates. This work has been done by combining field observation with laboratory sedimentary analysis to characterize the texture and structure of the sediments. Based on these studies, 12 layers and 9 sedimentary facies have been identified. The facies associations indicate a clear separation between GIa and GIb sub-units. GIa sub-unit is dominated by epiphreatic conditions and represents continuous relativity sedimentation during the Early Pleistocene; meanwhile, GIb shows important erosion events and facies with reworked materials that indicate vadose conditions during the Middle Pleistocene. This environmental change is related to the geomorphological evolution of the Arlanzón River. In addition, soft-sediment deformation structures have been described, including faults and low-angle folds...Funding for open access charge: Universidad de Málaga / CBU

Proyecto Jean Monnet. La Unión Europea y la seguridad: defensa de los espacios e intereses comunes

Este proyecto tiene la misión principal de identificar los grandes retos que enfrenta la Unión Europea (UE) y las sociedades que la integran, contribuyendo así al debate en torno a las acciones políticas a emprender por la UE y los instrumentos legislativos a adoptar. Además, este Proyecto, a través de las actividades que ha desarrollado, ha ampliado el concepto de “riesgos a la seguridad”, sobrepasando los estrictamente clásicos, lo que ha permitido analizar la situación de la UE en el contexto internacional, sus fortalezas y debilidades. Todo ello se ha hecho a través de la celebración de tres workshops y una conferencia final, todos ellos abiertos a la participación y enriquecimiento conjunto de académicos, expertos, representantes de instituciones públicas y privadas, estudiantes y sociedad civil en general. Los temas abordados por los workshops fueron los siguientes: Workshop I: El uso de los global commons y la seguridad de la UE (Instituto Complutense de Estudios Internacionales, ICEI, 22- 23 Septiembre 2016). Workshop II: Seguridad y derechos humanos (Facultad de Derecho, Sala de Juntas, 18-19 Noviembre 2016). Workshop III: Riesgos contemporáneos: el caso de la ciberseguridad (Instituto Complutense de Estudios Internacionales, ICEI, 27-28 Abril 2017). Esta recopilación, en forma de Occasional Paper del ICEI, recoge así buena parte de los temas debatidos en la conferencia final. De este modo, retos a la seguridad de la UE contemporáneos, tales como el Brexit y su impacto en el ciudadano, el terrorismo confrontado ante la protección de los derechos humanos, el cambio climático como reto securitario y como motor de pruebas del liderazgo europeo, la obtención de pruebas electrónicas o la necesidad de una regulación homogénea de la prostitución en la UE como mecanismo para actuar de forma coordinada frente a la trata de seres humanos, se han confrontado con aspectos clásicos de la seguridad europea, como el relativo al papel de la UE como actor global en el marco de la Política Exterior y de Seguridad Común (PESC), su actuación en el marco de una compleja operación de mantenimiento de la paz o la cooperación reforzada en materia de defensa. A la vista tanto de su estructura como de la procedencia y enfoque de los distintos autores, se puede fácilmente adivinar que no sólo se trata de una miscelánea, sino también –lo que era un objetivo fundamental del Proyecto- de una consideración de la seguridad de la UE desde perspectivas diferentes que, en todo caso, tuvieran en cuenta al ciudadano europeo como prioridad securitaria sin descuidar el respeto de sus libertades